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Recruiting Phase 3 Interventional

A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson's Disease

ClinicalTrials.gov ID: NCT07174310

Public ClinicalTrials.gov record NCT07174310. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced May 8, 2026, 3:55 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase III, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study to Evaluate the Efficacy and Safety of Intravenous Prasinezumab in Participants With Early-Stage Parkinson's Disease

Study identification

NCT ID
NCT07174310
Recruitment status
Recruiting
Study type
Interventional
Phase
Phase 3
Lead sponsor
Hoffmann-La Roche
Industry
Enrollment
900 participants

Conditions and interventions

Interventions

  • Placebo Drug
  • Prasinezumab Drug

Drug

Eligibility (public fields only)

Age range
50 Years to 85 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 23, 2025
Primary completion
Jun 29, 2029
Completion
Jun 29, 2031
Last update posted
May 5, 2026

2025 – 2031

United States locations

U.S. sites
37
U.S. states
23
U.S. cities
37
Facility City State ZIP Site status
University of Alabama at Birmingham Birmingham Alabama 35233 Recruiting
Barrow Neurological Institute Phoenix Arizona 85013 Recruiting
Neurology Center of North Orange County Fullerton California 92835 Recruiting
Keck School of Medicine of USC Los Angeles California 900033 Recruiting
Parkinson?s Research Centers of America ? Palo Alto Palo Alto California 94301 Recruiting
Profound Research LLC at The Neurology Center of Southern California Pasadena California 91105 Recruiting
UCSF Weill Institute for Neurosciences San Francisco California 94158 Recruiting
Rocky Mountain Movement Disorders Englewood Colorado 80113 Recruiting
Institute for Neurodegenerative Disorders New Haven Connecticut 06510 Recruiting
Georgetown University Washington D.C. District of Columbia 20007 Recruiting
JEM Research LLC Atlantis Florida 33462 Recruiting
Parkinson's Disease and Movement Disorders Center of Boca Raton Boca Raton Florida 33486 Recruiting
K2 - Villages Lady Lake Florida 32159 Recruiting
K2 Medical Research-Maitland Maitland Florida 32751 Recruiting
Charter Research - Winter Park/Orlando Orlando Florida 32803 Recruiting
Hawaii Pacific Neuroscience Honolulu Hawaii 96817 Recruiting
Northwestern University Feinberg School Of Medicine Chicago Illinois 60611 Recruiting
University of Kansas Medical Center Kansas City Kansas 66160 Recruiting
Massachusetts General Hospital Boston Massachusetts 02114 Recruiting
Quest Research Institute Farmington Hills Michigan 48334 Recruiting
Washington Uni School of Medicine St Louis Missouri 63110 Recruiting
Cleveland Clinic Lou Ruvo Las Vegas Nevada 89106 Recruiting
Renown Health Reno Nevada 89502 Recruiting
University of New Mexico Albuquerque New Mexico 87106 Recruiting
Dent Neurological Institute Amherst New York 14226 Recruiting
Parkinson's Research Centers of America - Long Island Commack New York 11725 Recruiting
Weill Cornell Medical College New York New York 10021 Recruiting
NeuroCare Center Canton Ohio 44718 Recruiting
Cleveland Clinic Cleveland Ohio 44195 Recruiting
The Movement Disorder Clinic of Oklahoma Tulsa Oklahoma 74136 Recruiting
Allegheny General Hospital Pittsburgh Pennsylvania 15212 Recruiting
Veracity Neuroscience Memphis Tennessee 38157 Recruiting
Texas Neurology PA Dallas Texas 75206 Recruiting
Central Texas Neurology Consultants Round Rock Texas 78681 Recruiting
University of Virginia Health System Charlottesville Virginia 22903 Recruiting
VCU Health North Hospital Richmond Virginia 23298 Recruiting
West Virginia University Morgantown West Virginia 26506 Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 105 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT07174310, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 5, 2026 · Synced May 8, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT07174310 live on ClinicalTrials.gov.

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