A Study of ROC-101 in Patients With Pulmonary Arterial Hypertension (PAH) and Pulmonary Hypertension Associated With Interstitial Lung Disease (ILD-PH) (ROCSTAR STUDY)

ClinicalTrials.gov ID: NCT07175038

Public ClinicalTrials.gov record NCT07175038. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

View official ClinicalTrials.gov record → Back to search

ClinicalTrials.gov public records Last synced Sep 10, 2026, 7:31 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2A, Open-Label Single Arm Multicenter Exploratory Study to Evaluate the Safety, Tolerability, and Efficacy of Oral Doses of ROC-101 in Patients With Pulmonary Arterial Hypertension (PAH) and Pulmonary Hypertension Associated With Interstitial Lung Disease (ILD-PH).

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This study evaluates the effect of ROC-101 in adults with either Pulmonary Arterial Hypertension (PAH) or Pulmonary Hypertension Associated with Interstitial Lung Disease (ILD-PH). Each eligible participant will receive standard of care (SOC) plus ROC-101 for a 24-week treatment period, followed by a long-term extension period of the study through the end of the program or marketing approval/authorization.

Study identification

NCT ID: NCT07175038
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 2
Lead sponsor: AllRock Bio, Inc.; Industry
Enrollment: 40 participants

Conditions and interventions

Conditions

Interventions

ROC-101 Drug

Drug

Eligibility (public fields only)

Age range: 18 Years to 80 Years
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Sep 30, 2025
Primary completion: Feb 28, 2027
Completion: Feb 28, 2029
Last update posted: Aug 9, 2026

2025 – 2029

United States locations

U.S. sites: 11
U.S. states: 11
U.S. cities: 11

Facility	City	State	ZIP	Site status
Arizona Pulmonary Specialists	Phoenix	Arizona	85012	Recruiting
University of California Davis Health	Rancho Cordova	California	95670	Recruiting
University of Colorado	Aurora	Colorado	80045	Recruiting
George Washington University Medical	Washington D.C.	District of Columbia	20037	Recruiting
Mayo Clinic of Florida	Jacksonville	Florida	32224	Recruiting
The University of Kansas Medical Center Research Institute	Kansas City	Kansas	66160	Recruiting
University of Michigan	Ann Arbor	Michigan	48109	Recruiting
Ohio State University	Columbus	Ohio	43210	Recruiting
Bend Memorial Clinic	Bend	Oregon	97701	Recruiting
Temple University	Philadelphia	Pennsylvania	19140	Recruiting
Houston Methodist Hospital	Houston	Texas	77030	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 12 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT07175038, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Aug 9, 2026 · Synced Sep 10, 2026

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT07175038 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →