Study of AZD0516 as Monotherapy and in Combination in Participants With Metastatic Prostate Cancer
Public ClinicalTrials.gov record NCT07181161. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Modular Phase I/IIa, Open-label, Multi-centre Study to Assess the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of AZD0516 as Monotherapy and in Combination With Anti-cancer Agents in Participants With Metastatic Prostate Cancer
Study identification
- NCT ID
- NCT07181161
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Lead sponsor
- AstraZeneca
- Industry
- Enrollment
- 177 participants
Conditions and interventions
Conditions
Interventions
- AZD0516 Drug
- AZD9574 Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 130 Years
- Sex
- Male
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 30, 2025
- Primary completion
- Jan 17, 2029
- Completion
- Jan 17, 2029
- Last update posted
- May 7, 2026
2025 – 2029
United States locations
- U.S. sites
- 11
- U.S. states
- 9
- U.S. cities
- 11
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Research Site | Fayetteville | Arkansas | 72703 | Recruiting |
| Research Site | Los Angeles | California | 90095 | Recruiting |
| Research Site | Towson | Maryland | 21204 | Suspended |
| Research Site | Boston | Massachusetts | 02114 | Recruiting |
| Research Site | Ann Arbor | Michigan | 48109 | Recruiting |
| Research Site | Detroit | Michigan | 48201 | Recruiting |
| Research Site | Buffalo | New York | 14263 | Suspended |
| Research Site | New York | New York | 10065 | Recruiting |
| Research Site | Providence | Rhode Island | 02906 | Recruiting |
| Research Site | Myrtle Beach | South Carolina | 29572 | Recruiting |
| Research Site | Houston | Texas | 77030 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 41 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07181161, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 7, 2026 · Synced May 9, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07181161 live on ClinicalTrials.gov.