LY4268989 (MORF-057) Co-Administered With Mirikizumab in Adults With Moderately to Severely Active Ulcerative Colitis:
Public ClinicalTrials.gov record NCT07186101. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Multicenter, Randomized, Double-Blind, Active-Controlled Study of LY4268989 (MORF-057) Co-Administered With Mirikizumab in Adults With Moderately to Severely Active Ulcerative Colitis
Study identification
- NCT ID
- NCT07186101
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Eli Lilly and Company
- Industry
- Enrollment
- 252 participants
Conditions and interventions
Conditions
Interventions
- LY4268989 Drug
- LY4268989 Placebo Drug
- Mirikizumab Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 9, 2025
- Primary completion
- Apr 30, 2027
- Completion
- Feb 28, 2029
- Last update posted
- Apr 16, 2026
2025 – 2029
United States locations
- U.S. sites
- 41
- U.S. states
- 19
- U.S. cities
- 40
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Mayo Clinic in Arizona - Scottsdale | Scottsdale | Arizona | 85259 | Not yet recruiting |
| Clinnova Research - Anaheim | Anaheim | California | 92805 | Recruiting |
| Om Research LLC | Lancaster | California | 93534 | Recruiting |
| Biopharma Informatic, LLC | Los Angeles | California | 90035 | Recruiting |
| Peak Gastroenterology Associates | Colorado Springs | Colorado | 80907 | Recruiting |
| NeoClinical Research | Hialeah | Florida | 33016 | Recruiting |
| Encore Borland-Groover Clinical Research | Jacksonville | Florida | 32256 | Recruiting |
| Clinical Research of Osceola | Kissimmee | Florida | 34741 | Recruiting |
| Florida Research Institute | Lakewood Rch | Florida | 34211 | Recruiting |
| Alliance Medical Research | Lighthouse PT | Florida | 33064 | Recruiting |
| Atlantic Medical Research | Margate | Florida | 33063 | Recruiting |
| Digestive and Liver Center of Florida | Orlando | Florida | 32825 | Recruiting |
| Center for Gastrointestinal Health - Fairview Heights | Belleville | Illinois | 62223 | Not yet recruiting |
| Northwestern University | Chicago | Illinois | 60611 | Not yet recruiting |
| Midtown Gastroenterology and Liver Disease | Des Plaines | Illinois | 60016 | Recruiting |
| GI Alliance - Glenview | Glenview | Illinois | 60026 | Recruiting |
| Gi Alliance - Gurnee | Gurnee | Illinois | 60031 | Recruiting |
| Gastroenterology Health Partners | New Albany | Indiana | 47150 | Recruiting |
| Gastroenterology Health Partners | Louisville | Kentucky | 40218 | Recruiting |
| Brigham and Women's Hospital | Boston | Massachusetts | 02215 | Recruiting |
| Clinical Research Institute of Michigan, LLC | Clinton Township | Michigan | 48038 | Recruiting |
| GI Associates - GIA and Endoscopy Center - Flowood | Flowood | Mississippi | 39232 | Recruiting |
| Digestive Disease Medicine of Central New York | Utica | New York | 13502 | Recruiting |
| Gastroenterology & Hepatology Specialists | Canton | Ohio | 44718 | Recruiting |
| Dayton Gastroenterology, LLC | Dayton | Ohio | 45415 | Recruiting |
| University Gastroenterology - Providence - West River Street | Providence | Rhode Island | 02904 | Recruiting |
| Gastroenterology Associates, P.A. of Greenville | Greenville | South Carolina | 29607 | Recruiting |
| Gastro One - Walnut Run Road | Cordova | Tennessee | 38018 | Recruiting |
| Texas Digestive Disease Consultants - Cedar Park | Cedar Park | Texas | 78613 | Recruiting |
| GI Alliance - Dallas - Gaston Avenue | Dallas | Texas | 75246 | Suspended |
| GI Alliance - Fort Worth | Fort Worth | Texas | 76104 | Recruiting |
| GI Alliance - Garland | Garland | Texas | 75044 | Recruiting |
| GI Alliance - Lubbock | Lubbock | Texas | 79410 | Recruiting |
| Southern Star Research Institute | San Antonio | Texas | 78229 | Recruiting |
| Tyler Research Institute | Tyler | Texas | 75701 | Recruiting |
| GI Alliance-Webster | Webster | Texas | 77598 | Recruiting |
| Care Access - Ogden | Ogden | Utah | 84403 | Recruiting |
| Clinical Research Partners, LLC | Richmond | Virginia | 23226 | Recruiting |
| GI Alliance - Richmond | Richmond | Virginia | 23229 | Recruiting |
| Carilion Clinic | Roanoke | Virginia | 24014 | Not yet recruiting |
| Washington Gastroenterology - Bellevue | Bellevue | Washington | 98004 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 108 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07186101, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 16, 2026 · Synced May 8, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07186101 live on ClinicalTrials.gov.