A Global Study Comparing Pulsed Field Ablation With Electrographic Flow Mapping Versus Posterior Wall Ablation for Persistent Atrial Fibrillation

ClinicalTrials.gov ID: NCT07187115

Public ClinicalTrials.gov record NCT07187115. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced Oct 21, 2026, 6:55 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Global Randomized Trial Comparing Pulsed Field Ablation of Pulmonary Veins Plus Extra-PV Sources Utilizing Electrographic Flow Mapping Versus Pulmonary Veins Plus Posterior Wall in Persistent Atrial Fibrillation Patients.

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to establish the safety of the pulsed field ablation (PFA) therapy of Pulmonary Veins and Electrographic Flow (EGF) identified extra-PV sources of atrial fibrillation (PVI + EGF ablation of sources) and to demonstrate its non-inferiority in effectiveness compared to PFA of Pulmonary Veins and LA Posterior Wall (PVI+ PWA) in the treatment of de novo symptomatic drug-refractory persistent atrial fibrillation (PersAF).

Study identification

NCT ID: NCT07187115
Recruitment status: Active, not recruiting
Study type: Interventional
Phase: Not applicable
Lead sponsor: Boston Scientific Corporation; Industry
Enrollment: 699 participants

Conditions and interventions

Conditions

Interventions

Device

Eligibility (public fields only)

Age range: 18 Years and older
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Nov 7, 2025 (Actual)
Primary completion: Jan 2027 (Estimated)
Completion: Jan 2027 (Estimated)
Last update posted: Sep 24, 2026

2025 – 2027

United States locations

U.S. sites: 11
U.S. states: 8
U.S. cities: 11

Facility	City	State	ZIP	Site status
Arrhythmia Research Group	Jonesboro	Arkansas	72401	—
Pacific Heart Institute	Santa Monica	California	90404	—
Piedmont Athens Regional	Athens	Georgia	30606	—
Emory University Hospital	Atlanta	Georgia	30308	—
St. Luke's Boise Medical Center	Boise	Idaho	83702	—
Mount Sinai Medical Center	New York	New York	10029	—
Cleveland Clinic Foundation	Cleveland	Ohio	44195	—
Ohio State University Medical Center	Columbus	Ohio	43210	—
University of Pittsburgh Medical Center	Pittsburgh	Pennsylvania	15213	—
Texas Cardiac Arrhythmia Research Foundation	Austin	Texas	78705	—
Christus Trinity Mother Frances Health System	Tyler	Texas	75701	—

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 4 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT07187115, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Sep 24, 2026 · Synced Oct 21, 2026

Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT07187115 live on ClinicalTrials.gov.

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