Effect of 2-HOBA in Persistent Immune Activation in Long COVID POTS
Public ClinicalTrials.gov record NCT07189936. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Mechanism of Isolevuglandin-Protein Adduct Formation in Persistent Immune Activation in Long COVID POTS
Study identification
- NCT ID
- NCT07189936
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Vanderbilt University Medical Center
- Other
- Enrollment
- 50 participants
Conditions and interventions
Conditions
Interventions
- To Measure Orthostatic Tachycardia after 28 days of Treatment with 2HOBA Diagnostic Test
- To Measure Orthostatic Tachycardia after 28 days of Treatment with Placebo Diagnostic Test
- To Measure Splanchnic venous capacitance after 28 days of Treatment with 2HOBA Diagnostic Test
- To Measure Splanchnic venous capacitance after 28 days of Treatment with Placebo Diagnostic Test
- To Measure levels of circulating monocyte/ T cell doublets at Baseline Drug
- To measure levels of circulating monocyte/ T cell doublets after 28 days of 2 HOBA treatment Drug
- To measure levels of circulating monocyte/ T cell doublets after 28 days of Placebo treatment Drug
Diagnostic Test · Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 17, 2025
- Primary completion
- Jun 29, 2028
- Completion
- Jun 29, 2029
- Last update posted
- Jan 21, 2026
2025 – 2029
United States locations
- U.S. sites
- 1
- U.S. states
- 1
- U.S. cities
- 1
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Cyndya Shibao | Nashville | Tennessee | 37027 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07189936, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 21, 2026 · Synced May 8, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07189936 live on ClinicalTrials.gov.