Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD) Characterized by an Eosinophilic Phenotype
Public ClinicalTrials.gov record NCT07190209. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2b/Phase 3, Randomized, Double-blind, Placebocontrolled, Multicenter Study, to Investigate the Efficacy and Safety of Lunsekimig in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD) Characterized by an Eosinophilic Phenotype
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a parallel, Phase 2b/Phase 3, 3-arm study to investigate the efficacy, safety, and tolerability of subcutaneous (SC) treatment with lunsekimig compared with placebo in adult participants (aged 40 to 80 years, inclusive) with inadequately controlled Chronic obstructive pulmonary disease (COPD) characterized by an eosinophilic phenotype. Participation to the study consists of 3 periods: * Screening period of up to 4 weeks * Randomized intervention period of approximately 48 weeks * Follow-up period: Approximately 8 weeks The study duration will be up to 60 weeks.
Study identification
- NCT ID
- NCT07190209
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 942 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 40 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 15, 2025
- Primary completion
- Nov 26, 2029
- Completion
- Jan 21, 2030
- Last update posted
- Sep 1, 2026
2025 – 2030
United States locations
- U.S. sites
- 66
- U.S. states
- 21
- U.S. cities
- 56
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Chandler Clinical Research Trials- Site Number : 8400025 | Chandler | Arizona | 85224 | Recruiting |
| Pulmonary Associates - Phoenix - East Bell Road- Site Number : 8400114 | Phoenix | Arizona | 85032 | Recruiting |
| Epic Medical Research - Surprise- Site Number : 8400096 | Surprise | Arizona | 85378 | Recruiting |
| IMAX Clinical Trials- Site Number : 8400109 | La Palma | California | 90623 | Recruiting |
| Long Beach Research Institute- Site Number : 8400027 | Long Beach | California | 90805 | Recruiting |
| Downtown L.A. Research Center- Site Number : 8400009 | Los Angeles | California | 90017 | Recruiting |
| Newport Native MD- Site Number : 8400003 | Newport Beach | California | 92663 | Recruiting |
| Paradigm Research - Redding- Site Number : 8400108 | Redding | California | 96001 | Recruiting |
| Amicis Research Center - Valencia- Site Number : 8400119 | Valencia | California | 91355 | Recruiting |
| Helix Biomedics- Site Number : 8400065 | Boynton Beach | Florida | 33435 | Recruiting |
| Beautiful Minds Clinical Research Center- Site Number : 8400017 | Cutler Bay | Florida | 33157 | Recruiting |
| Eastern Medical Group Research- Site Number : 8400020 | Fort Myers | Florida | 33908 | Recruiting |
| Premier Medical Associates- Site Number : 8400012 | Lady Lake | Florida | 32159 | Recruiting |
| University of Miami Dermatology Clinical Trials Unit- Site Number : 8400078 | Miami | Florida | 33125 | Recruiting |
| MCR Research- Site Number : 8400004 | Miami | Florida | 33126 | Recruiting |
| Nuren Medical & Research Center- Site Number : 8400030 | Miami | Florida | 33144 | Recruiting |
| My Community Research Center- Site Number : 8400164 | Miami | Florida | 33155 | Recruiting |
| Deluxe Health Center- Site Number : 8400010 | Miami Lakes | Florida | 33014 | Recruiting |
| Omega Research Consultants - Orlando - Forest City- Site Number : 8400015 | Orlando | Florida | 32810 | Recruiting |
| Broward Research Center - Pembroke Pines- Site Number : 8400053 | Pembroke Pines | Florida | 33024 | Recruiting |
| Clinical Research Trials of Florida- Site Number : 8400011 | Tampa | Florida | 33607 | Recruiting |
| Deluxe Health Center-Tampa- Site Number : 8400056 | Tampa | Florida | 33607 | Recruiting |
| Private Practice - Dr. David Kavtaradze- Site Number : 8400006 | Cordele | Georgia | 31015 | Recruiting |
| Primeway Clinical Research- Site Number : 8400121 | Fayetteville | Georgia | 30214 | Recruiting |
| University of Illinois-Chicago - College of Medicine- Site Number : 8400055 | Chicago | Illinois | 60612 | Recruiting |
| Avicenna Clinical Research- Site Number : 8400126 | Chicago Ridge | Illinois | 60415 | Recruiting |
| NorthShore Medical Group - Evanston ( Endeavor Health)- Site Number : 8400073 | Evanston | Illinois | 60201 | Recruiting |
| Indy Clinical Research- Site Number : 8400071 | Indianapolis | Indiana | 46268 | Recruiting |
| University of Kansas Medical Center- Site Number : 8400054 | Kansas City | Kansas | 66160 | Recruiting |
| Southern Clinical Research - Zachary- Site Number : 8400113 | Zachary | Louisiana | 70791 | Recruiting |
| University of Michigan Health System - Ann Arbor- Site Number : 8400090 | Ann Arbor | Michigan | 48109 | Recruiting |
| Pulmonary and Medicine Associates- Site Number : 8400007 | Warren | Michigan | 48088 | Recruiting |
| Mayo Clinic in Rochester - Minnesota- Site Number : 8400005 | Rochester | Minnesota | 55905 | Recruiting |
| Henderson Clinical Trials- Site Number : 8400026 | Henderson | Nevada | 89052 | Recruiting |
| Sierra Clinical Research - Las Vegas- Site Number : 8400028 | Las Vegas | Nevada | 89106 | Recruiting |
| Sanmora Bespoke Clinical Research Solutions- Site Number : 8400144 | East Orange | New Jersey | 07018 | Recruiting |
| New York Hospital Queens- Site Number : 8400058 | Flushing | New York | 11355 | Recruiting |
| Advanced Respiratory and Sleep Medicine - Hickory- Site Number : 8400013 | Hickory | North Carolina | 28601 | Recruiting |
| Atrium Health Wake Forest Baptist Pulmonary, Sleep And Allergy- Site Number : 8400048 | Winston-Salem | North Carolina | 27103 | Recruiting |
| Plains Clinical Research Center- Site Number : 8400140 | Fargo | North Dakota | 58104 | Recruiting |
| Dayton Clinical Research- Site Number : 8400124 | Dayton | Ohio | 45409 | Recruiting |
| Epic Medical Research - Chickasha- Site Number : 8400097 | Chickasha | Oklahoma | 73018 | Recruiting |
| Temple University Hospital - Main Campus- Site Number : 8400059 | Philadelphia | Pennsylvania | 19140-5103 | Recruiting |
| Preferred Primary Care Physicians - Pleasant Hills- Site Number : 8400092 | Pittsburgh | Pennsylvania | 15236 | Recruiting |
| AnMed Oglesby Center- Site Number : 8400074 | Anderson | South Carolina | 29621 | Recruiting |
| MD First Research - Lancaster- Site Number : 8400102 | Lancaster | South Carolina | 29720 | Recruiting |
| REX Clinical Trials - Beaumont- Site Number : 8400014 | Beaumont | Texas | 77701 | Recruiting |
| Novel Research - Bellaire- Site Number : 8400116 | Bellaire | Texas | 77401 | Recruiting |
| South Texas Medical Research Institute - TTS Research- Site Number : 8400018 | Boerne | Texas | 78006 | Recruiting |
| TEN20 Clinical Research - Carrollton- Site Number : 8400141 | Carrollton | Texas | 75010 | Recruiting |
| Corsicana Medical Research- Site Number : 8400134 | Corsicana | Texas | 75110 | Recruiting |
| Syri Research Center- Site Number : 8400069 | Cypress | Texas | 77065 | Recruiting |
| Texas Health Presbyterian Hospital Dallas- Site Number : 8400032 | Dallas | Texas | 75231 | Recruiting |
| Epic Medical Research - De Soto- Site Number : 8400095 | DeSoto | Texas | 75115 | Recruiting |
| Valley Institute of Research- Site Number : 8400118 | Harlingen | Texas | 78550 | Recruiting |
| Trio Clinical Trials- Site Number : 8400106 | Houston | Texas | 77008 | Recruiting |
| HDH Research- Site Number : 8400104 | Houston | Texas | 77022 | Recruiting |
| Baylor College of Medicine- Site Number : 8400076 | Houston | Texas | 77030 | Recruiting |
| Gulf Coast Clinical Research - Houston- Site Number : 8400049 | Houston | Texas | 77070 | Recruiting |
| Lumi Research - Kingwood- Site Number : 8400120 | Kingwood | Texas | 77339 | Recruiting |
| Syri Research Center- Site Number : 8400136 | Kingwood | Texas | 77339 | Recruiting |
| Radiance Clinical Research - Lampasas - West Avenue East- Site Number : 8400063 | Lampasas | Texas | 76550 | Recruiting |
| Discovery Clinical Trials - San Antonio- Site Number : 8400031 | San Antonio | Texas | 78229 | Recruiting |
| Bandera Family Health Care - San Antonio- Site Number : 8400021 | San Antonio | Texas | 78249 | Recruiting |
| Element Research Group- Site Number : 8400115 | San Antonio | Texas | 78257 | Recruiting |
| Tidewater Physicians Multispecialty Group Clinical Research - Williamsburg- Site Number : 8400081 | Williamsburg | Virginia | 23188 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 151 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07190209, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 1, 2026 · Synced Sep 2, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07190209 live on ClinicalTrials.gov.