ClinicalTrials.gov record
Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD), Characterized by an Eosinophilic Phenotype
ClinicalTrials.gov ID: NCT07190222
Public ClinicalTrials.gov record NCT07190222. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2b/Phase 3, Randomized, Double-blind, Placebo-controlled, Multicenter Study, to Investigate the Efficacy and Safety of Lunsekimig in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD) Characterized by an Eosinophilic Phenotype
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a parallel, Phase 2b/Phase 3, 3-arm study to investigate the efficacy, safety, and tolerability of subcutaneous (SC) treatment with lunsekimig compared with placebo in adult participants (aged 40 to 80 years, inclusive) with inadequately controlled Chronic obstructive pulmonary disease (COPD) characterized by an eosinophilic phenotype. Participation to the study consists of 3 periods: * Screening period of up to 4 weeks * Randomized intervention period of approximately 48 weeks * Follow-up period: Approximately 8 weeks The study duration will be up to 60 weeks.
Study identification
- NCT ID
- NCT07190222
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 942 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 40 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 17, 2025 (Actual)
- Primary completion
- Nov 27, 2029 (Estimated)
- Completion
- Jan 22, 2030 (Estimated)
- Last update posted
- Oct 1, 2026
2025 – 2030
United States locations
- U.S. sites
- 76
- U.S. states
- 26
- U.S. cities
- 63
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham- Site Number : 8400003 | Birmingham | Alabama | 35233 | Recruiting |
| Pulmonary Associates - Mobile- Site Number : 8400151 | Mobile | Alabama | 36608 | Recruiting |
| Tucson Clinical Research Institute- Site Number : 8400006 | Tucson | Arizona | 85712 | Recruiting |
| Ark Clinical Research- Site Number : 8400113 | Long Beach | California | 90815 | Recruiting |
| Inglewood Clinical- Site Number : 8400074 | Los Angeles | California | 90056 | Recruiting |
| Alliance Clinical - West Hills- Site Number : 8400067 | Los Angeles | California | 91307 | Recruiting |
| California Medical Research Associates - Northridge- Site Number : 8400089 | Northridge | California | 91324 | Recruiting |
| Acclaim Clinical Research- Site Number : 8400068 | San Diego | California | 92120 | Recruiting |
| Alpine Clinical Research Center - Boulder - 47th Street- Site Number : 8400005 | Boulder | Colorado | 80301 | Recruiting |
| Critical Care Pulmonary & Sleep Associates- Site Number : 8400081 | Lakewood | Colorado | 80228 | Recruiting |
| Howard University Hospital- Site Number : 8400080 | Washington D.C. | District of Columbia | 20060 | Recruiting |
| Meris Clinical Research- Site Number : 8400153 | Brandon | Florida | 33511 | Recruiting |
| Hillcrest Medical Research- Site Number : 8400082 | DeLand | Florida | 32720 | Recruiting |
| Finlay Medical Research - Greenacres- Site Number : 8400107 | Greenacres City | Florida | 33467 | Recruiting |
| Direct Helpers Research Center- Site Number : 8400057 | Hialeah | Florida | 33012 | Recruiting |
| University of Florida - Jacksonville- Site Number : 8400126 | Jacksonville | Florida | 32209 | Recruiting |
| Salud Clinical Services- Site Number : 8400109 | Lehigh Acres | Florida | 33936 | Recruiting |
| Pulmonary Specialists of the Palm Beaches- Site Number : 8400017 | Loxahatchee Groves | Florida | 33470 | Recruiting |
| Elite Clinical Research - Miami- Site Number : 8400167 | Miami | Florida | 33144 | Recruiting |
| DL Research Solutions- Site Number : 8400140 | Miami | Florida | 33155 | Recruiting |
| Phoenix Medical Research - Miami - 24th Street- Site Number : 8400027 | Miami | Florida | 33165 | Recruiting |
| Professional Research Center- Site Number : 8400046 | Miami | Florida | 33172 | Recruiting |
| Research Institute of South Florida- Site Number : 8400028 | Miami | Florida | 33173 | Recruiting |
| Innovations Biotech- Site Number : 8400019 | Miami | Florida | 33186 | Recruiting |
| Heuer M.D. Research- Site Number : 8400018 | Orlando | Florida | 32819 | Recruiting |
| Florida Institute for Clinical Research- Site Number : 8400001 | Orlando | Florida | 32825 | Recruiting |
| Avanza Medical Research Center- Site Number : 8400015 | Pensacola | Florida | 32503 | Recruiting |
| Hull and Hull Medical Specialists- Site Number : 8400002 | Plantation | Florida | 33324 | Recruiting |
| Windom Allergy, Asthma and Sinus Specialists- Site Number : 8400041 | Sarasota | Florida | 34239 | Recruiting |
| Stat Care Pulmonary and Sleep- Site Number : 8400138 | St. Petersburg | Florida | 33709 | Recruiting |
| Better Life Clinical Research- Site Number : 8400152 | Tampa | Florida | 33607 | Recruiting |
| Vicis Clinical Research- Site Number : 8400158 | Tampa | Florida | 33615 | Recruiting |
| Appalachian Clinical Research- Site Number : 8400060 | Adairsville | Georgia | 30103 | Recruiting |
| Christie Clinic in Champaign on University- Site Number : 8400023 | Champaign | Illinois | 61820 | Recruiting |
| Sneeze Wheeze & Itch Associates- Site Number : 8400020 | Normal | Illinois | 61761 | Recruiting |
| Peoria Pulmonary Associates Ltd- Site Number : 8400095 | Peoria | Illinois | 61603 | Recruiting |
| Asha Clinical Research - Munster- Site Number : 8400115 | Hammond | Indiana | 46324 | Recruiting |
| Ochsner LSU Health Shreveport - Academic Medical Center- Site Number : 8400083 | Shreveport | Louisiana | 71103 | Recruiting |
| Care Access - Shreveport - Youree Drive- Site Number : 8400007 | Shreveport | Louisiana | 71105 | Recruiting |
| Johns Hopkins Bayview Medical Center- Site Number : 8400076 | Baltimore | Maryland | 21224 | Recruiting |
| Lucida Clinical Trials- Site Number : 8400101 | New Bedford | Massachusetts | 02740 | Recruiting |
| Vitalis Clinical Research Center- Site Number : 8400040 | Allen Park | Michigan | 48101 | Recruiting |
| Bolt Clinical Research- Site Number : 8400086 | Brighton | Michigan | 48116 | Recruiting |
| Henry Ford Hospital- Site Number : 8400058 | Detroit | Michigan | 48202 | Recruiting |
| Pulmonary Research Institute of Southeast Michigan - Farmington Hills- Site Number : 8400161 | Farmington Hills | Michigan | 48336 | Recruiting |
| University of Missouri Health Care - Children's Hospital- Site Number : 8400150 | Columbia | Missouri | 65212 | Recruiting |
| Hannibal Regional Healthcare System- Site Number : 8400035 | Hannibal | Missouri | 63401 | Recruiting |
| Washington University- Site Number : 8400144 | St Louis | Missouri | 63110 | Recruiting |
| Excel Clinical Research - Las Vegas- Site Number : 8400070 | Las Vegas | Nevada | 89109 | Recruiting |
| AB Clinical Trials- Site Number : 8400075 | Las Vegas | Nevada | 89119 | Completed |
| Bioluminux Clinical Research - Hamilton, New Jersey- Site Number : 8400037 | Hamilton | New Jersey | 08690 | Recruiting |
| Rutgers Institute For Infectious & Inflammatory Diseases (I3d)- Site Number : 8400093 | Newark | New Jersey | 07103 | Recruiting |
| Trinity Medical, WNY- Site Number : 8400157 | Buffalo | New York | 14215 | Recruiting |
| Mid Hudson Medical Research - New Windsor- Site Number : 8400004 | New Windsor | New York | 12553 | Recruiting |
| East Carolina University- Site Number : 8400102 | Greenville | North Carolina | 27858 | Recruiting |
| Piedmont Healthcare - Family Medicine- Site Number : 8400022 | Statesville | North Carolina | 28625 | Recruiting |
| All-Trials Clinical Research- Site Number : 8400008 | Winston-Salem | North Carolina | 27103 | Recruiting |
| Asthma & Allergy Center - Toledo- Site Number : 8400110 | Toledo | Ohio | 43617 | Recruiting |
| Layrek Clinical Research- Site Number : 8400066 | Tulsa | Oklahoma | 74133 | Recruiting |
| The Oregon Clinic - Portland - Northwest 22nd Avenue- Site Number : 8400065 | Portland | Oregon | 97210 | Recruiting |
| Suburban Research Associates - Media- Site Number : 8400143 | Media | Pennsylvania | 19063 | Recruiting |
| MedTrial- Site Number : 8400010 | Columbia | South Carolina | 29204 | Recruiting |
| Chattanooga Research and Medicine- Site Number : 8400026 | Chattanooga | Tennessee | 37404 | Recruiting |
| Premier Research Center, Llc- Site Number : 8400146 | Hendersonville | Tennessee | 37075 | Recruiting |
| Solace Clinical Research- Site Number : 8400087 | Austin | Texas | 78759 | Recruiting |
| IntraCare- Site Number : 8400034 | Dallas | Texas | 75254 | Recruiting |
| Premier Pulmonary Critical Care and Sleep- Site Number : 8400111 | Denison | Texas | 75020 | Recruiting |
| El Paso Pulmonary Association- Site Number : 8400033 | El Paso | Texas | 79902 | Recruiting |
| Axsendo Clinical Research - Houston- Site Number : 8400054 | Houston | Texas | 77058 | Completed |
| Se Houston- Site Number : 8400120 | Houston | Texas | 77061 | Recruiting |
| Aavon Clinical Trials, Llc- Site Number : 8400166 | Houston | Texas | 77074 | Recruiting |
| Synergy Group US - Missouri City- Site Number : 8400119 | Missouri City | Texas | 77459 | Recruiting |
| Synergy Group US - Missouri City- Site Number : 8400133 | Missouri City | Texas | 77459 | Recruiting |
| Elligo Health Care, Hillcroft Medical Clinic Association- Site Number : 8400053 | Sugar Land | Texas | 77478 | Recruiting |
| Medrasa Clinical Research - Wylie- Site Number : 8400124 | Wylie | Texas | 75098 | Recruiting |
| Rheumatology & Pulmonary Clinic- Site Number : 8400012 | Beckley | West Virginia | 25801 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 239 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07190222, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 1, 2026 · Synced Oct 18, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT07190222 live on ClinicalTrials.gov.