Evaluation of Efficacy, Safety, and Tolerability of Povetacicept in Participants With Primary Membranous Nephropathy (pMN)
Public ClinicalTrials.gov record NCT07204275. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2b/3 Adaptive, Randomized, Active-controlled Study Evaluating the Efficacy, Safety, and Tolerability of Povetacicept Versus Calcineurin Inhibitor in the Treatment of Primary Membranous Nephropathy
Study identification
- NCT ID
- NCT07204275
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2, Phase 3
- Lead sponsor
- Vertex Pharmaceuticals Incorporated
- Industry
- Enrollment
- 176 participants
Conditions and interventions
Conditions
Interventions
- Povetacicept Drug
- Tacrolimus Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 29, 2025
- Primary completion
- Dec 28, 2028
- Completion
- Dec 28, 2028
- Last update posted
- Apr 23, 2026
2025 – 2028
United States locations
- U.S. sites
- 22
- U.S. states
- 14
- U.S. cities
- 21
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Renal Associates | Montgomery | Alabama | 36117 | Recruiting |
| Southwest Kidney Institute, PLC (SKI) - Surprise | Surprise | Arizona | 85374 | Recruiting |
| Academic Medical Research Institute (AMRI) | Los Angeles | California | 90022 | Recruiting |
| Valiance Clinical Research - Internal Medicine | Tarzana | California | 91356 | Recruiting |
| Western Nephrology & Metabolic Bone Disease PC | Arvada | Colorado | 80002 | Recruiting |
| Bioresearch Partner | Miami | Florida | 33127 | Recruiting |
| CTR Oakwater, LLC | Orlando | Florida | 32806 | Recruiting |
| Clinical Site Partners, LLC - Orlando | Winter Park | Florida | 32789 | Recruiting |
| DaVita Clinical Research Columbus | Columbus | Georgia | 31904 | Recruiting |
| Georgia Nephrology | Lawrenceville | Georgia | 30046 | Recruiting |
| CARE Institute-Boise Kidney | Boise | Idaho | 83706 | Recruiting |
| NANI Research | Hinsdale | Illinois | 60521 | Recruiting |
| DaVita Clinical Research Edina | Edina | Minnesota | 55435 | Recruiting |
| Kidney Specialists of Southern Nevada | Las Vegas | Nevada | 89107 | Recruiting |
| Carolina Nephrology Greenville | Greenville | South Carolina | 29605 | Recruiting |
| Carolina Nephrology, PA | Spartanburg | South Carolina | 29306 | Recruiting |
| El Paso Kidney Specialists | El Paso | Texas | 79902 | Recruiting |
| Provecta Research Network | Houston | Texas | 77027 | Recruiting |
| DaVita Clinical Research Houston | Houston | Texas | 77054 | Recruiting |
| Davita Clinical Research San Antonio | San Antonio | Texas | 78251 | Recruiting |
| Utah Kidney Research | Salt Lake City | Utah | 84115 | Recruiting |
| Milwaukee Neprologists, SC | Wauwatosa | Wisconsin | 53226 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 64 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07204275, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 23, 2026 · Synced Apr 29, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07204275 live on ClinicalTrials.gov.