ClinicalTrials.gov record
Recruiting Phase 2Phase 3 Interventional

Evaluation of Efficacy, Safety, and Tolerability of Povetacicept in Participants With Primary Membranous Nephropathy (pMN)

ClinicalTrials.gov ID: NCT07204275

Public ClinicalTrials.gov record NCT07204275. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Apr 29, 2026, 9:00 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2b/3 Adaptive, Randomized, Active-controlled Study Evaluating the Efficacy, Safety, and Tolerability of Povetacicept Versus Calcineurin Inhibitor in the Treatment of Primary Membranous Nephropathy

Study identification

NCT ID
NCT07204275
Recruitment status
Recruiting
Study type
Interventional
Phase
Phase 2, Phase 3
Lead sponsor
Vertex Pharmaceuticals Incorporated
Industry
Enrollment
176 participants

Conditions and interventions

Interventions

  • Povetacicept Drug
  • Tacrolimus Drug

Drug

Eligibility (public fields only)

Age range
18 Years to 75 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Sep 29, 2025
Primary completion
Dec 28, 2028
Completion
Dec 28, 2028
Last update posted
Apr 23, 2026

2025 – 2028

United States locations

U.S. sites
22
U.S. states
14
U.S. cities
21
Facility City State ZIP Site status
Renal Associates Montgomery Alabama 36117 Recruiting
Southwest Kidney Institute, PLC (SKI) - Surprise Surprise Arizona 85374 Recruiting
Academic Medical Research Institute (AMRI) Los Angeles California 90022 Recruiting
Valiance Clinical Research - Internal Medicine Tarzana California 91356 Recruiting
Western Nephrology & Metabolic Bone Disease PC Arvada Colorado 80002 Recruiting
Bioresearch Partner Miami Florida 33127 Recruiting
CTR Oakwater, LLC Orlando Florida 32806 Recruiting
Clinical Site Partners, LLC - Orlando Winter Park Florida 32789 Recruiting
DaVita Clinical Research Columbus Columbus Georgia 31904 Recruiting
Georgia Nephrology Lawrenceville Georgia 30046 Recruiting
CARE Institute-Boise Kidney Boise Idaho 83706 Recruiting
NANI Research Hinsdale Illinois 60521 Recruiting
DaVita Clinical Research Edina Edina Minnesota 55435 Recruiting
Kidney Specialists of Southern Nevada Las Vegas Nevada 89107 Recruiting
Carolina Nephrology Greenville Greenville South Carolina 29605 Recruiting
Carolina Nephrology, PA Spartanburg South Carolina 29306 Recruiting
El Paso Kidney Specialists El Paso Texas 79902 Recruiting
Provecta Research Network Houston Texas 77027 Recruiting
DaVita Clinical Research Houston Houston Texas 77054 Recruiting
Davita Clinical Research San Antonio San Antonio Texas 78251 Recruiting
Utah Kidney Research Salt Lake City Utah 84115 Recruiting
Milwaukee Neprologists, SC Wauwatosa Wisconsin 53226 Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 64 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT07204275, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 23, 2026 · Synced Apr 29, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT07204275 live on ClinicalTrials.gov.

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