A Long-Term Study of Navenibart in Participants With Hereditary Angioedema
Public ClinicalTrials.gov record NCT07204938. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3 Trial to Evaluate the Long-Term Safety and Efficacy of Navenibart in Participants With Hereditary Angioedema - ORBIT-EXPANSE
Study identification
- NCT ID
- NCT07204938
- Recruitment status
- Enrolling by invitation
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Astria Therapeutics, Inc.
- Industry
- Enrollment
- 145 participants
Conditions and interventions
Conditions
Interventions
- navenibart Drug
Drug
Eligibility (public fields only)
- Age range
- 12 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 30, 2025
- Primary completion
- May 31, 2031
- Completion
- Nov 30, 2031
- Last update posted
- May 17, 2026
2025 – 2031
United States locations
- U.S. sites
- 8
- U.S. states
- 6
- U.S. cities
- 8
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Site 2 | Scottsdale | Arizona | 85251 | — |
| Site 3 | Little Rock | Arkansas | 72205 | — |
| Site 7 | San Diego | California | 92122 | — |
| Site 4 | Santa Monica | California | 90404 | — |
| Site 1 | Walnut Creek | California | 94598 | — |
| Site 5 | Centennial | Colorado | 80112 | — |
| Site 6 | Cincinnati | Ohio | 45236 | — |
| Site 9 | Hershey | Pennsylvania | 17033 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 2 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07204938, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 17, 2026 · Synced May 20, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07204938 live on ClinicalTrials.gov.