A Study of TAK-188 in Adults With Advanced or Spreading Solid Tumors
Public ClinicalTrials.gov record NCT07205718. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
An Open-label, Dose Escalation and Expansion, Phase 1/2 Trial to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of TAK- 188, an Anti-CCR8 Antibody-Drug- Conjugate, as a Single Agent in Adult Participants With Locally Advanced or Metastatic Solid Tumors
Study identification
- NCT ID
- NCT07205718
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Lead sponsor
- Takeda
- Industry
- Enrollment
- 223 participants
Conditions and interventions
Conditions
Interventions
- TAK-188 Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 18, 2025
- Primary completion
- Dec 25, 2028
- Completion
- Dec 20, 2029
- Last update posted
- Apr 23, 2026
2025 – 2029
United States locations
- U.S. sites
- 15
- U.S. states
- 12
- U.S. cities
- 15
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| UCLA Health-Santa Monica Cancer Care (Cancer Care - Santa Monica) | Santa Monica | California | 90404 | Not yet recruiting |
| Yale School of Medicine - Smilow Cancer Hospital - Center for Thoracic Cancers | New Haven | Connecticut | 06511 | Recruiting |
| Florida Cancer Specialists - Lake Nona | Orlando | Florida | 32827 | Recruiting |
| Johns Hopkins | Baltimore | Maryland | 21231 | Not yet recruiting |
| Barbara Ann Karmanos Cancer Institute | Detroit | Michigan | 48201 | Recruiting |
| START Midwest | Grand Rapids | Michigan | 49546 | Recruiting |
| Washington University | St Louis | Missouri | 63108 | Recruiting |
| University Hospitals Cleveland Medical Center | Cleveland | Ohio | 44106-1716 | Recruiting |
| Providence Cancer Institute, Franz Clinic | Portland | Oregon | 97213-2933 | Not yet recruiting |
| Fox Chase Cancer Center | Philadelphia | Pennsylvania | 19111-2497 | Recruiting |
| SCRI Oncology | Nashville | Tennessee | 37203 | Recruiting |
| MD Anderson Cancer Center | Houston | Texas | 77030-4000 | Not yet recruiting |
| NEXT Dallas | Irving | Texas | 75039 | Recruiting |
| START San Antonio | San Antonio | Texas | 78229 | Recruiting |
| NEXT Virginia | Fairfax | Virginia | 22031 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07205718, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 23, 2026 · Synced May 8, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07205718 live on ClinicalTrials.gov.