A Safety and Efficacy Study of a One-time Intravitreal Injection of SAR446597 in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration
Public ClinicalTrials.gov record NCT07215234. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 1/2, Study to Evaluate the Safety, Tolerability, and Efficacy of One-time Intravitreal Dose of SAR446597 in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration
Study identification
- NCT ID
- NCT07215234
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Lead sponsor
- Sanofi
- Industry
- Enrollment
- 104 participants
Conditions and interventions
Conditions
Interventions
- SAR446597 Drug
- Sham Comparator Drug
Drug
Eligibility (public fields only)
- Age range
- 60 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 8, 2025
- Primary completion
- Oct 12, 2027
- Completion
- Jul 21, 2032
- Last update posted
- Apr 20, 2026
2025 – 2032
United States locations
- U.S. sites
- 14
- U.S. states
- 7
- U.S. cities
- 13
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Associated Retina Consultants - Peoria- Site Number : 8400011 | Peoria | Arizona | 85381 | Recruiting |
| Retina Macula Institute of Arizona- Site Number : 8400028 | Scottsdale | Arizona | 85255 | Recruiting |
| Vitreo Retinal Associates - Gainesville- Site Number : 8400004 | Gainesville | Florida | 32607 | Recruiting |
| Retina Vitreous Associates of Florida - St. Petersburg- Site Number : 8400002 | St. Petersburg | Florida | 33711 | Recruiting |
| University Retina - Lemont- Site Number : 8400005 | Lemont | Illinois | 60439 | Recruiting |
| The Retina Group of Washington - Chevy Chase- Site Number : 8400009 | Chevy Chase | Maryland | 20815 | Recruiting |
| Cumberland Valley Retina Consultants - Hagerstown- Site Number : 8400003 | Hagerstown | Maryland | 21740 | Recruiting |
| Oregon Retina- Site Number : 8400017 | Eugene | Oregon | 97401 | Recruiting |
| Mid Atlantic Retina - Bethlehem- Site Number : 8400031 | Bethlehem | Pennsylvania | 18017-9412 | Recruiting |
| Austin Clinical Research - Austin - Anderson Mill Road- Site Number : 8400007 | Austin | Texas | 78750 | Recruiting |
| Retina Consultants of Texas - Bellaire- Site Number : 8400019 | Bellaire | Texas | 77401 | Recruiting |
| Retina Foundation of the Southwest- Site Number : 8400001 | Dallas | Texas | 75231 | Recruiting |
| Texas Retina Associates - Dallas- Site Number : 8400006 | Dallas | Texas | 75231 | Recruiting |
| Retinal Consultants of Texas - San Antonio- Site Number : 8400012 | San Antonio | Texas | 78240 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 3 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07215234, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 20, 2026 · Synced May 8, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07215234 live on ClinicalTrials.gov.