ClinicalTrials.gov record
A Phase 2, Randomized, Placebo Controlled, Multicenter, Masked Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacodynamics of Multidose APL 3007 in Combination With Syfovre/Pegcetacoplan (APL-2) in Patients Diagnosed With Geographic Atrophy Secondary to Age Related Macular Degeneratio
ClinicalTrials.gov ID: NCT07215390
Public ClinicalTrials.gov record NCT07215390. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
ClinicalTrials.gov public records Last synced May 5, 2026, 12:51 AM EDT
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Randomized, Placebo Controlled, Multicenter, Masked Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacodynamics of Multidose APL 3007 in Combination With Syfovre/Pegcetacoplan (APL-2) in Patients Diagnosed With Geographic Atrophy Secondary to Age Related Macular Degeneration
Study identification
- NCT ID
- NCT07215390
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Apellis Pharmaceuticals, Inc.
- Industry
- Enrollment
- 240 participants
Conditions and interventions
Interventions
- APL-3007, pegcetacoplan (APL-2) Drug
- Placebo, Syfovre Other
Drug · Other
Eligibility (public fields only)
- Age range
- 60 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 22, 2025
- Primary completion
- May 31, 2027
- Completion
- Oct 31, 2027
- Last update posted
- Mar 29, 2026
2025 – 2027
United States locations
- U.S. sites
- 43
- U.S. states
- 17
- U.S. cities
- 42
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Barnet Dulaney Perkins Eye Center (01018) | Mesa | Arizona | 85206 | Recruiting |
| Associated Retina Consultants - Phoenix | Phoenix | Arizona | 85020 | Recruiting |
| Retinal Research Institute, LLC (01021) | Phoenix | Arizona | 85053 | Recruiting |
| California Retina Consultants (CRC) - Bakersfield Office | Bakersfield | California | 93309 | Recruiting |
| The Retina Partners - Encino | Encino | California | 07003 | Recruiting |
| Retina Consultants of Orange County - Fullerton Office | Fullerton | California | 93825 | Recruiting |
| Salehi Retina Institute, Inc dba Retina Associate or Southern California (01034) | Huntington Beach | California | 92647 | Recruiting |
| Retina Consultants San Diego | Poway | California | 92064 | Recruiting |
| Orange County Retina Medical Group | Santa Ana | California | 92705 | Recruiting |
| Bay Area Retina Associates - Walnut Creek | Walnut Creek | California | 94598 | Recruiting |
| Colorado Retina Associates, PLLC | Lakewood | Colorado | 80228 | Recruiting |
| Advanced Vision Research Institute | Longmont | Colorado | 80503 | Recruiting |
| Florida Retina Institute - Orlando (01053) | Orlando | Florida | 32806 | Recruiting |
| Retina Specialty Institute - Pensacola | Pensacola | Florida | 32503 | Recruiting |
| Retina Vitreous Associates of Florida (RVA) - Saint Petersburg | St. Petersburg | Florida | 33711 | Recruiting |
| Center for Retina and Macular Disease (01026) | Winter Haven | Florida | 33880 | Recruiting |
| Southeast Retina Center | Augusta | Georgia | 30909 | Recruiting |
| Illinois Retina Associates, S.C. - Oak Park (01061) | Oak Park | Illinois | 60304 | Recruiting |
| Retina Consultants P.C. | Indianapolis | Indiana | 46214 | Recruiting |
| Retina Associates New Orleans - Jefferson Parish Location | Metairie | Louisiana | 70001 | Recruiting |
| Cumberland Valley Retina Consultants (CVRC) | Hagerstown | Maryland | 21740 | Recruiting |
| Mississippi Retina Associates | Madison | Mississippi | 39110 | Recruiting |
| Long Island Vitreoretinal Consultants - Westbury | Long Island City | New York | 11590 | Recruiting |
| Retina Assocaites of Cleveland, Inc (01048) | Cleveland | Ohio | 44122 | Recruiting |
| Verum Research, LLC | Eugene | Oregon | 97401 | Recruiting |
| EyeHealth Northwest | Portland | Oregon | 97225 | Recruiting |
| Mid Atlantic Retina - Philadelphia (01017) | Philadelphia | Pennsylvania | 19107 | Recruiting |
| Charleston Neuroscience Institute LLC - Ladson | Ladson | South Carolina | 29456 | Recruiting |
| Charleston Neuroscience Institute, LLC - Mount Pleasant (01051) | Mt. Pleasant | South Carolina | 29464 | Recruiting |
| Retina Consultants of Texas - Abilene (01035) | Abilene | Texas | 79606 | Recruiting |
| Austin Retina Associates | Austin | Texas | 78705 | Recruiting |
| Retina Consultants of Texas - Bellaire (01067) | Bellaire | Texas | 77401 | Recruiting |
| Texas Retina Associates | Dallas | Texas | 75231 | Recruiting |
| Retina Consultants of Texas - Katy | Katy | Texas | 77494 | Recruiting |
| Valley Retina Institute- McAllen (01076) | McAllen | Texas | 78503 | Recruiting |
| Austin Retina Associates - Round Rock (01032) | Round Rock | Texas | 78681 | Recruiting |
| Retina Consultants of Texas - San Antonio Medical Center | San Antonio | Texas | 78240 | Recruiting |
| Austin Retina Associate (01046) | San Marcos | Texas | 78666 | Recruiting |
| Retina Consultants of Texas (01055) | Schertz | Texas | 78154 | Recruiting |
| Retina Center of Texas - Southlake | Southlake | Texas | 76092 | Recruiting |
| Retina Consultants of Texas - The Woodlands | The Woodlands | Texas | 73384 | Recruiting |
| Tyler Retina Consultants | Tyler | Texas | 75703 | Recruiting |
| University of Wisconsin Health - University Station Clinic | Madison | Wisconsin | 53705 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07215390, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 29, 2026 · Synced May 5, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07215390 live on ClinicalTrials.gov.