ClinicalTrials.gov record
A Phase 2, Randomized, Placebo Controlled, Multicenter, Masked Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacodynamics of Multidose APL 3007 in Combination With Syfovre/Pegcetacoplan (APL-2) in Patients Diagnosed With Geographic Atrophy Secondary to Age Related Macular Degeneratio
ClinicalTrials.gov ID: NCT07215390
Public ClinicalTrials.gov record NCT07215390. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Randomized, Placebo Controlled, Multicenter, Masked Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacodynamics of Multidose APL 3007 in Combination With Syfovre/Pegcetacoplan (APL-2) in Patients Diagnosed With Geographic Atrophy Secondary to Age Related Macular Degeneration
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
A Phase 2, Randomized, Placebo-controlled, Multicenter, Masked Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacodynamics of Multidose APL-3007 in Combination with Syfovre/Pegcetacoplan (APL-2) in Patients Diagnosed with Geographic Atrophy Secondary to Age-Related Macular Degeneration
Study identification
- NCT ID
- NCT07215390
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 240 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 60 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 22, 2025
- Primary completion
- Jun 24, 2027
- Completion
- Oct 31, 2027
- Last update posted
- Jun 23, 2026
2025 – 2027
United States locations
- U.S. sites
- 78
- U.S. states
- 24
- U.S. cities
- 71
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Associated Retina Consultants (01065) | Gilbert | Arizona | 85297 | Recruiting |
| Barnet Dulaney Perkins Eye Center (01018) | Mesa | Arizona | 85206 | Recruiting |
| Associated Retina Consultants - Phoenix | Phoenix | Arizona | 85020 | Recruiting |
| Retinal Research Institute, LLC (01021) | Phoenix | Arizona | 85053 | Recruiting |
| Research Network Arizona | Scottsdale | Arizona | 46214 | Recruiting |
| California Retina Consultants (CRC) - Bakersfield Office | Bakersfield | California | 93309 | Recruiting |
| Retinal Diagnostic Center | Campbell | California | 95008 | Recruiting |
| The Retina Partners - Encino | Encino | California | 07003 | Recruiting |
| Retina Consultants of Orange County - Fullerton Office | Fullerton | California | 93825 | Recruiting |
| Salehi Retina Institute, Inc dba Retina Associate or Southern California (01034) | Huntington Beach | California | 92647 | Recruiting |
| Salehi Retina Institute, Inc. Dba Retina Associates of Southern California (01034) | Huntington Beach | California | 92647 | Recruiting |
| California Retina Consultants (01054) | Oxnard | California | 93036 | Recruiting |
| Retina Consultants San Diego | Poway | California | 92064 | Recruiting |
| Orange County Retina Medical Group | Santa Ana | California | 92705 | Recruiting |
| Retina Macula Institute | Torrance | California | 90503 | Recruiting |
| Bay Area Retina Associates - Walnut Creek | Walnut Creek | California | 94598 | Recruiting |
| Colorado Retina Associates, PLLC | Lakewood | Colorado | 80228 | Recruiting |
| Advanced Vision Research Institute | Longmont | Colorado | 80503 | Recruiting |
| Connecticut Eye Consultants, PC (01074) | Danbury | Connecticut | 06810 | Recruiting |
| ClearVista Clinical Research, LLC (01096) | Bayonet Point | Florida | 34667 | Recruiting |
| Advance Retina Institute | Bonita Springs | Florida | 34134 | Recruiting |
| Florida Retina Institute (01053) | Orlando | Florida | 32806 | Recruiting |
| Florida Retina Institute - Orlando (01053) | Orlando | Florida | 32806 | Recruiting |
| Retina Specialty Institute - Pensacola | Pensacola | Florida | 32503 | Recruiting |
| Eye Associates of Pinellas (01020) | Pinellas Park | Florida | 33782 | Recruiting |
| Retina Vitreous Associates of Florida (RVA) - Saint Petersburg | St. Petersburg | Florida | 33711 | Recruiting |
| Retina Vitreous Associates of Florida | Tampa | Florida | 33617 | Recruiting |
| Center for Retina and Macular Disease (01026) | Winter Haven | Florida | 33880 | Recruiting |
| Southeast Retina Center | Augusta | Georgia | 30909 | Recruiting |
| Illinois Retina Associates, S.C. - Oak Park (01061) | Oak Park | Illinois | 60304 | Recruiting |
| Midwest Eye Institute (01066) | Carmel | Indiana | 46032 | Recruiting |
| Vision Research Solutions | Indianapolis | Indiana | 21044 | Recruiting |
| Advancing Research International. LLC (01090) | Indianapolis | Indiana | 46214 | Recruiting |
| Retina Consultants P.C. | Indianapolis | Indiana | 46214 | Recruiting |
| Retina Associates New Orleans - Jefferson Parish Location | Metairie | Louisiana | 70001 | Recruiting |
| The Retina Care Center | Baltimore | Maryland | 21209 | Recruiting |
| The Retina Group of Washington (01089) | Chevy Chase | Maryland | 29902 | Recruiting |
| Cumberland Valley Retina Consultants (CVRC) | Hagerstown | Maryland | 21740 | Recruiting |
| Retina Specialists | Towson | Maryland | 21204 | Recruiting |
| Mississippi Retina Associates | Madison | Mississippi | 39110 | Recruiting |
| Envision Ocular, LLC (01027) | Bloomfield | New Jersey | 07003 | Recruiting |
| Mid Atlantic Retina (01039) | Cherry Hill | New Jersey | 08034 | Recruiting |
| NJ Retina (01031) | Edison | New Jersey | 08820 | Recruiting |
| NJ Retina (01030) | Toms River | New Jersey | 08755 | Recruiting |
| Vision Research Center Eye Associates of New Mexico (01023) | Albuquerque | New Mexico | 87109 | Recruiting |
| Long Island Vitreoretinal Consultants (01050) | Great Neck | New York | 11021 | Recruiting |
| Long Island Vitreoretinal Consultants - Westbury | Long Island City | New York | 11590 | Recruiting |
| Retina Assocaites of Cleveland, Inc (01048) | Cleveland | Ohio | 44122 | Recruiting |
| Retina Associates of Cleveland | Cleveland | Ohio | 44130 | Recruiting |
| Verum Research, LLC | Eugene | Oregon | 97401 | Recruiting |
| EyeHealth Northwest | Portland | Oregon | 97225 | Recruiting |
| EyeHealth Northwest (01006) | Portland | Oregon | 97228 | Recruiting |
| Cascade Medical Research Institute, LLC (01070) | Springfield | Oregon | 97477 | Recruiting |
| Eye Care Specialists | Kingston | Pennsylvania | 18704 | Recruiting |
| Mid Atlantic Retina - Philadelphia (01017) | Philadelphia | Pennsylvania | 19107 | Recruiting |
| Charleston Neuroscience Institute (01037) | Beaufort | South Carolina | 29902 | Recruiting |
| Retina Consultants of Carolina, PA (01073) | Greenville | South Carolina | 29605 | Recruiting |
| Charleston Neuroscience Institute LLC - Ladson | Ladson | South Carolina | 29456 | Recruiting |
| Charleston Neuroscience Institute, LLC - Mount Pleasant (01051) | Mt. Pleasant | South Carolina | 29464 | Recruiting |
| Ophthalmology Ltd. (01084) | Sioux Falls | South Dakota | 57108 | Recruiting |
| Tennessee Retina, PC (01063) | Nashville | Tennessee | 37203 | Recruiting |
| Retina Consultants of Texas - Abilene (01035) | Abilene | Texas | 79606 | Recruiting |
| Austin Retina Associates | Austin | Texas | 78705 | Recruiting |
| Retina Consultants of Texas - Bellaire (01067) | Bellaire | Texas | 77401 | Recruiting |
| Texas Retina Associates | Dallas | Texas | 75231 | Recruiting |
| Retina Consultants of Texas - Katy | Katy | Texas | 77494 | Recruiting |
| Valley Retina Institute- McAllen (01076) | McAllen | Texas | 78503 | Recruiting |
| Austin Retina Associates - Round Rock (01032) | Round Rock | Texas | 78681 | Recruiting |
| Retina Consultants of Texas - San Antonio Medical Center | San Antonio | Texas | 78240 | Recruiting |
| Austin Retina Associate (01046) | San Marcos | Texas | 78666 | Recruiting |
| Retina Consultants of Texas (01055) | Schertz | Texas | 78154 | Recruiting |
| Retina Center of Texas - Southlake | Southlake | Texas | 76092 | Recruiting |
| Retina Consultants of Texas - The Woodlands | The Woodlands | Texas | 73384 | Recruiting |
| Tyler Retina Consultants | Tyler | Texas | 75703 | Recruiting |
| Retina Associates of Utah (01052) | Salt Lake City | Utah | 84107 | Recruiting |
| Salt Lake Retina (01044) | West Jordan | Utah | 84088 | Recruiting |
| Piedmont Eye Center (01097) | Lynchburg | Virginia | 24502 | Recruiting |
| University of Wisconsin Health - University Station Clinic | Madison | Wisconsin | 53705 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07215390, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 23, 2026 · Synced Sep 7, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07215390 live on ClinicalTrials.gov.