A Clinical Study of Enlicitide in Participants With High Cholesterol (MK-0616-037)
Public ClinicalTrials.gov record NCT07216482. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Enlicitide Decanoate Coadministered With Rosuvastatin in Adults With Hyperlipidemia
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Researchers designed a study medicine called enlicitide to lower low-density lipoprotein cholesterol (LDL-C). In this study, researchers want to learn about giving enlicitide with another medicine called rosuvastatin. Rosuvastatin is a standard (usual) treatment to lower LDL-C. The goal of this study is to learn if enlicitide given with rosuvastatin works better than placebo on lowering LDL-C in a person's blood. A placebo looks like the study medicine but has no study medicine in it. Using a placebo helps researchers better understand the effects of a study medicine.
Study identification
- NCT ID
- NCT07216482
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 996 participants
Conditions and interventions
Conditions
Interventions
- Enlicitide Drug
- Rosuvastatin Drug
- Placebo for Enlicitide Drug
- Placebo for Rosuvastatin Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 64 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 11, 2025 (Actual)
- Primary completion
- Aug 3, 2026 (Actual)
- Completion
- Nov 5, 2026 (Estimated)
- Last update posted
- Sep 1, 2026
2025 – 2026
United States locations
- U.S. sites
- 35
- U.S. states
- 17
- U.S. cities
- 33
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Central Research Associates ( Site 0009) | Birmingham | Alabama | 35205 | — |
| G&L Research ( Site 0024) | Foley | Alabama | 36535 | — |
| Synexus Clinical Research US, Inc. - Phoenix Central ( Site 0030) | Phoenix | Arizona | 85020 | — |
| Alliance for Multispecialty Research LLC ( Site 0049) | Tempe | Arizona | 85281 | — |
| Chemidox Clinical Trials ( Site 0008) | Lancaster | California | 93534 | — |
| Clinical Trials Research ( Site 0036) | Sacramento | California | 95821 | — |
| Legacy Clinical Trials ( Site 0044) | Colorado Springs | Colorado | 80909 | — |
| Alliance for Multispecialty Research, LLC ( Site 0040) | Fort Myers | Florida | 33912 | — |
| Soffer Health Institute ( Site 0046) | Hollywood | Florida | 33020 | — |
| East Coast Institute for Research ( Site 0041) | Lake City | Florida | 32055 | — |
| Inpatient Research Clinic ( Site 0017) | Miami Lakes | Florida | 33014 | — |
| Clinical Research Trials of Florida ( Site 0001) | Tampa | Florida | 33607 | — |
| Clinical Site Partners LLC, dba CSP Orlando ( Site 0014) | Winter Park | Florida | 32789 | — |
| Trialmed ( Site 0026) | Chicago | Illinois | 60602 | — |
| Great Lakes Clinical Trials - Ravenswood ( Site 0018) | Chicago | Illinois | 60640 | — |
| Midwest Institute For Clinical Research ( Site 0033) | Indianapolis | Indiana | 46260-5310 | — |
| Alliance for Multispecialty Research, LLC ( Site 0048) | Newton | Kansas | 67114 | — |
| Cotton O'Neil Clinical Research Center ( Site 0006) | Topeka | Kansas | 66606 | — |
| L-MARC Research Center ( Site 0004) | Louisville | Kentucky | 40213 | — |
| Jubilee Clinical Research ( Site 0031) | Las Vegas | Nevada | 89106 | — |
| Cardiovascular Associates of the Delaware Valley ( Site 0035) | Elmer | New Jersey | 08318 | — |
| New Mexico Clinical Research & Osteoporosis Center, Inc. ( Site 0027) | Albuquerque | New Mexico | 87106-4725 | — |
| Alliance for Multispecialty Research, LLC - Norman ( Site 0043) | Norman | Oklahoma | 73069 | — |
| Cardiology Consultants of Philadelphia Yardley ( Site 0016) | Yardley | Pennsylvania | 19067 | — |
| Provecta Research Network LLC ( Site 0022) | Houston | Texas | 77027 | — |
| Permian Research Foundation ( Site 0005) | Odessa | Texas | 79761 | — |
| LinQ Research ( Site 0025) | Pearland | Texas | 77584 | — |
| Clinical Trials of Texas, Inc. ( Site 0010) | San Antonio | Texas | 78229 | — |
| Stone Oak, LLC dba Discovery Clinical Trials (DCT) ( Site 0021) | San Antonio | Texas | 78258 | — |
| LinQ Research - Tomball ( Site 0047) | Tomball | Texas | 77375 | — |
| Conquest Research ( Site 0045) | Arlington | Virginia | 22205 | — |
| Manassas Clinical Research Center ( Site 0002) | Manassas | Virginia | 20110 | — |
| Health Research of Hampton Roads, Inc. ( Site 0013) | Newport News | Virginia | 23606 | — |
| National Clinical Research, Inc ( Site 0028) | Richmond | Virginia | 23294 | — |
| Rainier Clinical Research ( Site 0023) | Renton | Washington | 98057 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 52 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07216482, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 1, 2026 · Synced Oct 30, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT07216482 live on ClinicalTrials.gov.