Effect of Donor Diabetes and Other Factors on Corneal Transplant Endothelial Cell Loss and Success at 5 Years
Public ClinicalTrials.gov record NCT07217249. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Diabetes Endothelial Keratoplasty Study (DEKS): Impact of Diabetes and Other Predictors on Corneal Transplant Endothelial Cell Loss and Success
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This multi-center clinical trial is designed to assess the association of diabetes in a cornea donor with transplant success and loss of endothelial cells 5 years following Descemet membrane endothelial keratoplasty (DMEK). Study eyes are assigned to receive either a cornea from a donor without diabetes or a cornea from a donor with diabetes in a masked fashion.
Study identification
- NCT ID
- NCT07217249
- Recruitment status
- Enrolling by invitation
- Study type
- Interventional
- Phase
- Not applicable
- Enrollment
- 570 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 30 Years to 93 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 3, 2025 (Actual)
- Primary completion
- Dec 30, 2029 (Estimated)
- Completion
- Apr 30, 2030 (Estimated)
- Last update posted
- Feb 27, 2026
2025 – 2030
United States locations
- U.S. sites
- 14
- U.S. states
- 10
- U.S. cities
- 13
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Georgia Eye Partners | Atlanta | Georgia | 30189 | — |
| Price Vision Group | Indianapolis | Indiana | 46260 | — |
| University of Iowa Hospitals and Clinics | Iowa City | Iowa | 52242 | — |
| Kansas City Eye Clinic | Overland Park | Kansas | 66204 | — |
| Mid-Atlantic Cornea Consultants | Baltimore | Maryland | 21204 | — |
| The Wilmer Eye Institute/Johns Hopkins | Baltimore | Maryland | 21287 | — |
| University of Michigan/Kellogg Eye Center | Ann Arbor | Michigan | 48105 | — |
| Verdier Eye Center | Grand Rapids | Michigan | 49546 | — |
| Minnesota Eye Consultants | Bloomington | Minnesota | 55431 | — |
| Mayo Clinic | Rochester | Minnesota | 55905 | — |
| Associated Eye Care | Stillwater | Minnesota | 55082 | — |
| Moyes Eye Center | Kansas City | Missouri | 64154 | — |
| Legacy Devers Eye Institute | Portland | Oregon | 97210 | — |
| Ophthalmic Partners | Bala-Cynwyd | Pennsylvania | 19004 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07217249, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 27, 2026 · Synced Oct 23, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT07217249 live on ClinicalTrials.gov.