A Clinical Study of Sotatercept (MK-7962) in People With Pulmonary Arterial Hypertension (MK-7962-038)
Public ClinicalTrials.gov record NCT07218029. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
An Open-label Long-term Follow-up Study to Evaluate the Effects of Sotatercept When Added to Background Pulmonary Arterial Hypertension (PAH) Therapy for the Treatment of PAH (MK-7962-038)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Researchers are looking for more ways to treat PAH. In PAH, the blood vessels in the lungs become thick and narrow, which makes it harder for blood to flow. This causes high blood pressure in the lungs and overworks the heart. PAH can make it hard to breathe and be active. Some standard (usual) treatments for PAH can treat symptoms of PAH but do not stop PAH from getting worse. Sotatercept is a study medicine designed to treat PAH. It is a targeted therapy, which is a treatment that works on certain proteins that play a role in causing PAH. This is a long-term follow-up (LTFU) study. People who took part in certain other studies testing sotatercept for PAH may be able to join this study. The goal of this study is to learn about the long-term safety of sotatercept and if people tolerate it when taken with standard PAH treatment over a longer period of time.
Study identification
- NCT ID
- NCT07218029
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 815 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 12, 2021 (Actual)
- Primary completion
- Dec 7, 2028 (Estimated)
- Completion
- Dec 7, 2028 (Estimated)
- Last update posted
- Oct 8, 2026
2021 – 2028
United States locations
- U.S. sites
- 36
- U.S. states
- 21
- U.S. cities
- 33
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Pulmonary Associates, PA ( Site 1008) | Phoenix | Arizona | 85032 | — |
| Arizona Pulmonary Specialists ( Site 1010) | Scottsdale | Arizona | 85258 | — |
| University of Arizona ( Site 1006) | Tucson | Arizona | 85724-0001 | — |
| University of California San Diego Health ( Site 1002) | La Jolla | California | 92039 | — |
| UC Irvine Health Medical Center ( Site 1086) | Orange | California | 92868 | — |
| UC Davis - Medial Center ( Site 1064) | Sacramento | California | 95817 | — |
| UCSF Helen Diller Medical Center at Parnassus Heights ( Site 1019) | San Francisco | California | 94143 | — |
| Jeffrey S. Sager, MD Medical Corporation ( Site 1060) | Santa Barbara | California | 93105-5316 | — |
| Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center ( Site 1028) | Torrance | California | 90502 | — |
| University of Colorado Hospital ( Site 1013) | Aurora | Colorado | 80045 | — |
| George Washington University Medical Faculty Associates ( Site 1025) | Washington D.C. | District of Columbia | 20037 | — |
| Mayo Clinic Jacksonville ( Site 1045) | Jacksonville | Florida | 32224 | — |
| AdventHealth Orlando ( Site 1058) | Orlando | Florida | 32803 | — |
| Tampa General Hospital ( Site 1043) | Tampa | Florida | 33606 | — |
| The Emory Clinic ( Site 1030) | Atlanta | Georgia | 30322 | — |
| University of Kansas Medical Center ( Site 1020) | Kansas City | Kansas | 66160 | — |
| Norton Pulmonary Specialists ( Site 1066) | Louisville | Kentucky | 40202 | — |
| Johns Hopkins University ( Site 1036) | Baltimore | Maryland | 21287 | — |
| Tufts Medical Center ( Site 1012) | Boston | Massachusetts | 02111 | — |
| Brigham and Women's Hospital ( Site 1014) | Boston | Massachusetts | 02115 | — |
| University of Minnesota ( Site 1062) | Minneapolis | Minnesota | 55455 | — |
| University Of Nebraska Medical Center ( Site 1053) | Omaha | Nebraska | 68198-5990 | — |
| Weill Cornell Medical Center ( Site 1046) | New York | New York | 10021 | — |
| Duke University Medical Center ( Site 1026) | Durham | North Carolina | 27710-4000 | — |
| The Carl and Edyth Lindner Center for Research and Education at the Christ Hospital ( Site 1001) | Cincinnati | Ohio | 45219 | — |
| University of Cincinnati Medical Center ( Site 1035) | Cincinnati | Ohio | 45219 | — |
| Cleveland Clinic Main ( Site 1065) | Cleveland | Ohio | 44195 | — |
| Ohio State University Wexner Medical Center ( Site 1032) | Columbus | Ohio | 43210 | — |
| Oregon Health & Science University ( Site 1054) | Portland | Oregon | 97239 | — |
| University of Pittsburgh Medical Center - Presbyterian Hosp. ( Site 1059) | Pittsburgh | Pennsylvania | 15213 | — |
| Rhode Island Hospital ( Site 1033) | Providence | Rhode Island | 02903 | — |
| Medical University of South Carolina ( Site 1003) | Charleston | South Carolina | 29425 | — |
| University of Texas Southwestern Medical Center ( Site 1038) | Dallas | Texas | 75390 | — |
| CHI St. Luke's Health Baylor College of Medicine Medical Center ( Site 1044) | Houston | Texas | 77030 | — |
| Houston Methodist Hospital ( Site 1009) | Houston | Texas | 77030 | — |
| Froedtert Hospital & the Medical College of Wisconsin ( Site 1051) | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 101 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07218029, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 8, 2026 · Synced Oct 31, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT07218029 live on ClinicalTrials.gov.