A Clinical Study of Sotatercept (MK-7962) in People With Pulmonary Arterial Hypertension (MK-7962-038)
Public ClinicalTrials.gov record NCT07218029. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
An Open-label Long-term Follow-up Study to Evaluate the Effects of Sotatercept When Added to Background Pulmonary Arterial Hypertension (PAH) Therapy for the Treatment of PAH (MK-7962-038)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Researchers are looking for more ways to treat PAH. In PAH, the blood vessels in the lungs become thick and narrow, which makes it harder for blood to flow. This causes high blood pressure in the lungs and overworks the heart. PAH can make it hard to breathe and be active. Some standard (usual) treatments for PAH can treat symptoms of PAH but do not stop PAH from getting worse. Sotatercept is a study medicine designed to treat PAH. It is a targeted therapy, which is a treatment that works on certain proteins that play a role in causing PAH. This is a long-term follow-up (LTFU) study. People who took part in certain other studies testing sotatercept for PAH may be able to join this study. The goal of this study is to learn about the long-term safety of sotatercept and if people tolerate it when taken with standard PAH treatment over a longer period of time.
Study identification
- NCT ID
- NCT07218029
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 815 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 11, 2021
- Primary completion
- Dec 6, 2028
- Completion
- Dec 6, 2028
- Last update posted
- Sep 8, 2026
2021 – 2028
United States locations
- U.S. sites
- 35
- U.S. states
- 20
- U.S. cities
- 32
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Pulmonary Associates, PA ( Site 1008) | Phoenix | Arizona | 85032 | Active, not recruiting |
| Arizona Pulmonary Specialists ( Site 1010) | Scottsdale | Arizona | 85258 | Recruiting |
| University of Arizona ( Site 1006) | Tucson | Arizona | 85724-0001 | Active, not recruiting |
| University of California San Diego Health ( Site 1002) | La Jolla | California | 92039 | Active, not recruiting |
| UC Irvine Health Medical Center ( Site 1086) | Orange | California | 92868 | Active, not recruiting |
| UC Davis - Medial Center ( Site 1064) | Sacramento | California | 95817 | Recruiting |
| UCSF Helen Diller Medical Center at Parnassus Heights ( Site 1019) | San Francisco | California | 94143 | Active, not recruiting |
| Jeffrey S. Sager, MD Medical Corporation ( Site 1060) | Santa Barbara | California | 93105-5316 | Active, not recruiting |
| Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center ( Site 1028) | Torrance | California | 90502 | Active, not recruiting |
| University of Colorado Hospital ( Site 1013) | Aurora | Colorado | 80045 | Active, not recruiting |
| George Washington University Medical Faculty Associates ( Site 1025) | Washington D.C. | District of Columbia | 20037 | Active, not recruiting |
| Mayo Clinic Jacksonville ( Site 1045) | Jacksonville | Florida | 32224 | Active, not recruiting |
| AdventHealth Orlando ( Site 1058) | Orlando | Florida | 32803 | Active, not recruiting |
| Tampa General Hospital ( Site 1043) | Tampa | Florida | 33606 | Active, not recruiting |
| University of Kansas Medical Center ( Site 1020) | Kansas City | Kansas | 66160 | Active, not recruiting |
| Norton Pulmonary Specialists ( Site 1066) | Louisville | Kentucky | 40202 | Active, not recruiting |
| Johns Hopkins University ( Site 1036) | Baltimore | Maryland | 21287 | Active, not recruiting |
| Tufts Medical Center ( Site 1012) | Boston | Massachusetts | 02111 | Active, not recruiting |
| Brigham and Women's Hospital ( Site 1014) | Boston | Massachusetts | 02115 | Recruiting |
| University of Minnesota ( Site 1062) | Minneapolis | Minnesota | 55455 | Active, not recruiting |
| University Of Nebraska Medical Center ( Site 1053) | Omaha | Nebraska | 68198-5990 | Active, not recruiting |
| Weill Cornell Medical Center ( Site 1046) | New York | New York | 10021 | Active, not recruiting |
| Duke University Medical Center ( Site 1026) | Durham | North Carolina | 27710-4000 | Active, not recruiting |
| The Carl and Edyth Lindner Center for Research and Education at the Christ Hospital ( Site 1001) | Cincinnati | Ohio | 45219 | Active, not recruiting |
| University of Cincinnati Medical Center ( Site 1035) | Cincinnati | Ohio | 45219 | Active, not recruiting |
| Cleveland Clinic Main ( Site 1065) | Cleveland | Ohio | 44195 | Active, not recruiting |
| Ohio State University Wexner Medical Center ( Site 1032) | Columbus | Ohio | 43210 | Active, not recruiting |
| Oregon Health & Science University ( Site 1054) | Portland | Oregon | 97239 | Active, not recruiting |
| University of Pittsburgh Medical Center - Presbyterian Hosp. ( Site 1059) | Pittsburgh | Pennsylvania | 15213 | Active, not recruiting |
| Rhode Island Hospital ( Site 1033) | Providence | Rhode Island | 02903 | Active, not recruiting |
| Medical University of South Carolina ( Site 1003) | Charleston | South Carolina | 29425 | Recruiting |
| University of Texas Southwestern Medical Center ( Site 1038) | Dallas | Texas | 75390 | Active, not recruiting |
| CHI St. Luke's Health Baylor College of Medicine Medical Center ( Site 1044) | Houston | Texas | 77030 | Active, not recruiting |
| Houston Methodist Hospital ( Site 1009) | Houston | Texas | 77030 | Active, not recruiting |
| Froedtert Hospital & the Medical College of Wisconsin ( Site 1051) | Milwaukee | Wisconsin | 53226 | Active, not recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 101 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07218029, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 8, 2026 · Synced Sep 16, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07218029 live on ClinicalTrials.gov.