A Study of Brenipatide in Participants With Moderate-to-Severe Alcohol Use Disorder
Public ClinicalTrials.gov record NCT07219966. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Multicenter, Randomized, Double-Blind Study to Investigate the Efficacy and Safety of Brenipatide Compared With Placebo for the Treatment of Adult Participants With Moderate-to-Severe Alcohol Use Disorder (RENEW-ALC-1)
Study identification
- NCT ID
- NCT07219966
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Eli Lilly and Company
- Industry
- Enrollment
- 1,100 participants
Conditions and interventions
Conditions
Interventions
- LY3537031 Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 14, 2025
- Primary completion
- Mar 31, 2028
- Completion
- Mar 31, 2028
- Last update posted
- Apr 16, 2026
2025 – 2028
United States locations
- U.S. sites
- 30
- U.S. states
- 18
- U.S. cities
- 28
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Parkway Medical Center | Birmingham | Alabama | 35215 | Recruiting |
| Headlands Research - Scottsdale | Scottsdale | Arizona | 85260 | Recruiting |
| Woodland International Research Group | Little Rock | Arkansas | 72211 | Not yet recruiting |
| UCLA Clinical & Translational Research Center (CTRC) | Los Angeles | California | 90095 | Recruiting |
| Artemis Institute for Clinical Research | San Diego | California | 92123 | Recruiting |
| UCSF Weill Institute for Neurosciences - Substance Use Disorders Clinic - Mission Bay | San Francisco | California | 94158 | Recruiting |
| Mountain Mind - Denver | Denver | Colorado | 80202 | Recruiting |
| Accel Research Sites - Lakeland Clinical Research Unit | Lakeland | Florida | 33803 | Recruiting |
| K2 Medical Research - Maitland | Maitland | Florida | 32751 | Recruiting |
| K2 Medical Research ORLANDO | Maitland | Florida | 32751 | Recruiting |
| Life Arc Research Centers - Miami | Miami | Florida | 33126 | Recruiting |
| Wellness Research Center | Miami | Florida | 33135 | Recruiting |
| Life Medical Research Group Corp | Miami Gardens | Florida | 33014 | Recruiting |
| Charter Research - Orlando | Orlando | Florida | 32803 | Recruiting |
| K2 Medical Research - Tampa | Tampa | Florida | 33634 | Recruiting |
| Re:Cognition Health - Chicago | Chicago | Illinois | 60611 | Recruiting |
| Maryland Treatment Centers - Mountain Manor Treatment Center | Baltimore | Maryland | 21229 | Recruiting |
| Maryland Treatment Centers - Avery Road Treatment Center | Rockville | Maryland | 20853 | Not yet recruiting |
| Adams Clinical Boston | Boston | Massachusetts | 02116 | Recruiting |
| Adams Clinical Bronx | The Bronx | New York | 10461 | Recruiting |
| North Star Medical Research | Middleburg Heights | Ohio | 44130 | Recruiting |
| Penn Medicine: University of Pennsylvania Health System | Philadelphia | Pennsylvania | 19104 | Recruiting |
| K2 Medical Research - East Providence | East Providence | Rhode Island | 02914 | Recruiting |
| Avera Research Institute - Sioux Falls | Sioux Falls | South Dakota | 57108 | Recruiting |
| UT Southwestern Medical Center | Dallas | Texas | 75390 | Recruiting |
| Adams Clinical Dallas | DeSoto | Texas | 75115 | Recruiting |
| Pillar Clinical Research - Richardson | Richardson | Texas | 75080 | Recruiting |
| Alpine Research Organization | Clinton | Utah | 84015 | Recruiting |
| Re:Cognition Health | Fairfax | Virginia | 22031 | Recruiting |
| University of Washington Medical Center - Montlake | Seattle | Washington | 98195 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 88 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07219966, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 16, 2026 · Synced May 9, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07219966 live on ClinicalTrials.gov.