A Study of Pasritamig With Docetaxel Versus Docetaxel in Participants With Metastatic Castration-Resistant Prostate Cancer
Public ClinicalTrials.gov record NCT07225946. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3 Randomized, Open-label Study of Pasritamig (JNJ-78278343), a T-cell-redirecting Agent Targeting Human Kallikrein 2, With Docetaxel Versus Docetaxel for Metastatic Castration-resistant Prostate Cancer
Study identification
- NCT ID
- NCT07225946
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Janssen Research & Development, LLC
- Industry
- Enrollment
- 800 participants
Conditions and interventions
Conditions
Interventions
- Docetaxel Drug
- Pasritamig Drug
- Prednisone Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 18, 2025
- Primary completion
- Nov 18, 2027
- Completion
- Jul 19, 2029
- Last update posted
- Apr 13, 2026
2025 – 2029
United States locations
- U.S. sites
- 32
- U.S. states
- 20
- U.S. cities
- 30
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Arizona Clinical Trials | Chandler | Arizona | 85225 | Recruiting |
| Arkansas Urology | Little Rock | Arkansas | 72211 | Recruiting |
| University Of California San Diego | La Jolla | California | 92037 | Recruiting |
| USC Norris Comprehensive Cancer Center | Los Angeles | California | 90033 | Recruiting |
| Valkyrie Clinical Trials | Los Angeles | California | 90067 | Recruiting |
| Kaiser Permanente Southern California | Riverside | California | 92505 | Recruiting |
| Providence Saint John s Health Center | Santa Monica | California | 90404 | Recruiting |
| Rocky Mountain Cancer Centers | Aurora | Colorado | 80012 | Recruiting |
| Grand Valley Oncology | Grand Junction | Colorado | 81505 | Recruiting |
| Colorado Clinical Research | Lakewood | Colorado | 80228 | Recruiting |
| Florida Cancer Specialists | Sarasota | Florida | 34232 | Recruiting |
| Duly Health and Care | Lisle | Illinois | 60532 | Recruiting |
| Cancer Center of Kansas Heritage Plaza Medical Building | Wichita | Kansas | 67214 | Recruiting |
| East Jefferson General Hospital | Metairie | Louisiana | 70006 | Recruiting |
| Profound Research LLC at Cancer and Leukemia Center | Sterling Heights | Michigan | 48314 | Recruiting |
| HealthPartners Frauenshuh Cancer Center CRC West | Saint Louis Park | Minnesota | 55426 | Recruiting |
| HealthPartners Cancer Center at Regions Hospital CRC East | Saint Paul | Minnesota | 55101 | Recruiting |
| NHO Revive Research Institute, LLC | Lincoln | Nebraska | 68506 | Recruiting |
| Rutgers Cancer Institute of New Jersey | New Brunswick | New Jersey | 08901 | Recruiting |
| Oregon Urology Institute | Springfield | Oregon | 97477 | Recruiting |
| Lehigh Valley Hospital | Allentown | Pennsylvania | 18103 | Recruiting |
| MidLantic Urology | Bala-Cynwyd | Pennsylvania | 19004 | Recruiting |
| Penn State Milton S. Hershey Medical Center | Hershey | Pennsylvania | 17033 | Recruiting |
| University Of Pittsburgh Medical Center UPMC Hillman Cancer Center | Pittsburgh | Pennsylvania | 15232 | Recruiting |
| Carolina Urologic Research Center | Myrtle Beach | South Carolina | 29572 | Recruiting |
| Avera Medical Group | Sioux Falls | South Dakota | 57105 | Recruiting |
| Tennessee Cancer Specialists | Knoxville | Tennessee | 37909 | Recruiting |
| Houston Metro Urology | Houston | Texas | 77027 | Recruiting |
| Texas Oncology 1 | Sugar Land | Texas | 77479 | Recruiting |
| Virginia Cancer Specialists | Fairfax | Virginia | 22031 | Recruiting |
| Fred Hutch Cancer Center Sloan Clinic 2 | Seattle | Washington | 98109 | Recruiting |
| Fred Hutchinson Cancer Research Center | Seattle | Washington | 98109 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 65 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07225946, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 13, 2026 · Synced Apr 29, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07225946 live on ClinicalTrials.gov.