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Recruiting Phase 1 Interventional

A Study of BG-75098 Alone and in Combination With Other Agents in Adults With Advanced Solid Tumors

ClinicalTrials.gov ID: NCT07226349

Public ClinicalTrials.gov record NCT07226349. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 11, 2026, 10:57 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1a/1b, Open-Label Study Evaluating the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Antitumor Activity of BG-75098 Alone and in Combination With Other Agents in Patients With Advanced Solid Tumors

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to evaluate safety, tolerability, pharmacokinetics (PK), pharmacodynamics, and preliminary antitumor activity of BG-75098 alone and in combination with BGB-43395 and fulvestrant in participants with advanced solid tumors.

Study identification

NCT ID
NCT07226349
Recruitment status
Recruiting
Study type
Interventional
Phase
Phase 1
Lead sponsor
BeOne Medicines
Industry
Enrollment
105 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Dec 10, 2025
Primary completion
Oct 31, 2028
Completion
Oct 31, 2028
Last update posted
Sep 10, 2026

2025 – 2028

United States locations

U.S. sites
7
U.S. states
6
U.S. cities
6
Facility City State ZIP Site status
University of Alabama At Birmingham Hospital Birmingham Alabama 35294-0004 Recruiting
Yale Cancer Center New Haven Connecticut 06510 Recruiting
Sidney Kimmel Comprehensive Cancer At Johns Hopkins Baltimore Maryland 21287 Recruiting
Massachusetts General Hospital Boston Massachusetts 02114 Recruiting
The University of Texas Md Anderson Cancer Center Houston Texas 77030-4009 Recruiting
Next Oncology Houston Houston Texas 77054 Recruiting
Medical College of Wisconsin Milwaukee Wisconsin 53226-3522 Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 15 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT07226349, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Sep 10, 2026 · Synced Sep 11, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT07226349 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →