Maridebart Cafraglutide Versus Placebo in Adult Participants With Obstructive Sleep Apnea Not on Positive Airway Pressure (PAP) Therapy

ClinicalTrials.gov ID: NCT07226765

Public ClinicalTrials.gov record NCT07226765. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced May 6, 2026, 8:45 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 3 Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy, Safety, and Tolerability of Maridebart Cafraglutide in Adult Participants With Obstructive Sleep Apnea Not on Positive Airway Pressure Therapy and Living With Overweight or Obesity (MARITIME-OSA-2)

Study identification

NCT ID: NCT07226765
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 3
Lead sponsor: Amgen; Industry
Enrollment: 250 participants

Conditions and interventions

Conditions

Obstructive Sleep Apnea

Interventions

Maridebart cafraglutide Drug
Placebo Drug

Drug

Eligibility (public fields only)

Age range: 18 Years to 99 Years
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Nov 24, 2025
Primary completion: Sep 28, 2027
Completion: Sep 12, 2028
Last update posted: May 4, 2026

2025 – 2028

United States locations

U.S. sites: 13
U.S. states: 8
U.S. cities: 13

Facility	City	State	ZIP	Site status
Valley Clinical Trials	Northridge	California	91325	Recruiting
Peninsula Research Associates	Rolling Hills Estates	California	90274	Recruiting
Teradan Clinical Trials	Brandon	Florida	33511	Recruiting
Destiny Research Center	Palmetto Bay	Florida	33157	Recruiting
Clinical Research Center Of Florida	Pompano Beach	Florida	33060	Recruiting
NeuroTrials Research	Atlanta	Georgia	30328	Recruiting
Basil Clinical	Laurelton	New York	11413	Recruiting
Monroe Biomedical Research	Monroe	North Carolina	28112	Recruiting
CTI Clinical Research Center	Cincinnati	Ohio	45212	Recruiting
FutureSearch Trials of Neurology	Austin	Texas	78731	Recruiting
Epic Medical Research - DeSoto	DeSoto	Texas	75115	Recruiting
Sleep Therapy & Research Center	San Antonio	Texas	78229	Recruiting
Northwest Clinical Research Center	Bellevue	Washington	98007	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 29 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT07226765, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted May 4, 2026 · Synced May 6, 2026

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT07226765 live on ClinicalTrials.gov.

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