ClinicalTrials.gov record
Not yet recruiting Phase 1 Interventional

A Study of LY4584180 in Adult Participants With Previously Treated Blood Cancers

ClinicalTrials.gov ID: NCT07226843

Public ClinicalTrials.gov record NCT07226843. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 4, 2026, 10:56 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

NOVA-BCL6-1, A First-in-Human, Multicenter Phase 1a/1b Study to Investigate Safety, Tolerability, Pharmacokinetics, and Efficacy of LY4584180 in Adult Participants With Previously Treated Hematologic Malignancies

Study identification

NCT ID
NCT07226843
Recruitment status
Not yet recruiting
Study type
Interventional
Phase
Phase 1
Lead sponsor
Eli Lilly and Company
Industry
Enrollment
360 participants

Conditions and interventions

Interventions

  • LY4584180 Drug
  • Rituximab Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 31, 2026
Primary completion
Jan 31, 2027
Completion
Nov 30, 2029
Last update posted
Apr 16, 2026

2026 – 2029

United States locations

U.S. sites
21
U.S. states
14
U.S. cities
19
Facility City State ZIP Site status
Mayo Clinic - Scottsdale Scottsdale Arizona 85259
City of Hope Duarte California 91010
University of California, Los Angeles (UCLA) - Medical Center Los Angeles California 90059
University of California, San Francisco (UCSF) - Helen Diller Family Comprehensive Cancer Center San Francisco California 94158
Colorado Blood Cancer Institute Denver Colorado 80218
University of Miami - Sylvester Cancer Center Miami Florida 33136
Florida Cancer Specialists - Sarasota Sarasota Florida 34236
Emory University Hospital Atlanta Georgia 30322
Massachusetts General Hospital Boston Massachusetts 02114
Dana-Farber Cancer Institute Boston Massachusetts 02215
Mayo Clinic - Rochester Rochester Minnesota 55905
Columbia University New York New York 10032
University of Rochester Rochester New York 14618
The Ohio State University (OSU) Columbus Ohio 43210
Oregon Health & Science University (OHSU) Portland Oregon 97239
Sarah Cannon Research Institute Nashville Tennessee 37203
Vanderbilt University Medical Center Nashville Tennessee 37212
Texas Oncology - DFW (Sammons CC) Dallas Texas 75246
Baylor College of Medicine Houston Texas 77030
University of Washington - Fred Hutchinson Cancer Center (Seattle Cancer Care Alliance) Seattle Washington 98195
Froedtert Hospital and the Medical College of Wisconsin Milwaukee Wisconsin 53226

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 24 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT07226843, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 16, 2026 · Synced May 4, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT07226843 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →