A Study of LY4584180 in Adult Participants With Previously Treated Blood Cancers
Public ClinicalTrials.gov record NCT07226843. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
NOVA-BCL6-1, A First-in-Human, Multicenter Phase 1a/1b Study to Investigate Safety, Tolerability, Pharmacokinetics, and Efficacy of LY4584180 in Adult Participants With Previously Treated Hematologic Malignancies
Study identification
- NCT ID
- NCT07226843
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 1
- Lead sponsor
- Eli Lilly and Company
- Industry
- Enrollment
- 460 participants
Conditions and interventions
Interventions
- LY4584180 Drug
- Rituximab Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 16, 2026
- Primary completion
- Mar 31, 2027
- Completion
- Jan 31, 2030
- Last update posted
- May 18, 2026
2026 – 2030
United States locations
- U.S. sites
- 21
- U.S. states
- 14
- U.S. cities
- 19
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Mayo Clinic - Scottsdale | Scottsdale | Arizona | 85259 | Not yet recruiting |
| City of Hope | Duarte | California | 91010 | Recruiting |
| University of California, Los Angeles (UCLA) - Medical Center | Los Angeles | California | 90059 | Not yet recruiting |
| University of California, San Francisco (UCSF) - Helen Diller Family Comprehensive Cancer Center | San Francisco | California | 94158 | Not yet recruiting |
| Colorado Blood Cancer Institute | Denver | Colorado | 80218 | Recruiting |
| University of Miami - Sylvester Cancer Center | Miami | Florida | 33136 | Not yet recruiting |
| Florida Cancer Specialists - Sarasota | Sarasota | Florida | 34236 | Recruiting |
| Emory University Hospital | Atlanta | Georgia | 30322 | Recruiting |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | Recruiting |
| Dana-Farber Cancer Institute | Boston | Massachusetts | 02215 | Recruiting |
| Mayo Clinic - Rochester | Rochester | Minnesota | 55905 | Not yet recruiting |
| Columbia University | New York | New York | 10032 | Not yet recruiting |
| University of Rochester | Rochester | New York | 14618 | Recruiting |
| The Ohio State University (OSU) | Columbus | Ohio | 43210 | Recruiting |
| Oregon Health & Science University (OHSU) | Portland | Oregon | 97239 | Not yet recruiting |
| Sarah Cannon Research Institute | Nashville | Tennessee | 37203 | Recruiting |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37212 | Recruiting |
| Texas Oncology - DFW (Sammons CC) | Dallas | Texas | 75246 | Not yet recruiting |
| Baylor College of Medicine | Houston | Texas | 77030 | Not yet recruiting |
| University of Washington - Fred Hutchinson Cancer Center (Seattle Cancer Care Alliance) | Seattle | Washington | 98195 | Not yet recruiting |
| Froedtert Hospital and the Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | Not yet recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 25 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07226843, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 18, 2026 · Synced May 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07226843 live on ClinicalTrials.gov.