Symbiotic-Lung-04: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Extensive-Stage Small Cell Lung Cancer
Public ClinicalTrials.gov record NCT07226999. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A GLOBAL PHASE 2/3 INTERVENTIONAL STUDY OF PF-08634404 IN COMBINATION WITH CHEMOTHERAPY IN PARTICIPANTS WITH EXTENSIVE STAGE SMALL CELL LUNG CANCER
Study identification
- NCT ID
- NCT07226999
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2, Phase 3
- Enrollment
- 550 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 8, 2025
- Primary completion
- Jun 13, 2030
- Completion
- Mar 10, 2034
- Last update posted
- Apr 19, 2026
2025 – 2034
United States locations
- U.S. sites
- 20
- U.S. states
- 4
- U.S. cities
- 16
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Highlands Oncology Group | Fayetteville | Arkansas | 72703 | Recruiting |
| Highlands Oncology Group | Rogers | Arkansas | 72758 | Recruiting |
| Highlands Oncology Group | Springdale | Arkansas | 72762 | Recruiting |
| BRCR Coral Springs | Coral Springs | Florida | 33065 | Recruiting |
| BRCR Global - Coral Springs | Coral Springs | Florida | 33065 | Recruiting |
| Mid Florida Hematology and Oncology Center | Orange City | Florida | 32763 | Recruiting |
| BRCR Global - Tamarac | Tamarac | Florida | 33321 | Recruiting |
| Clario | Philadelphia | Pennsylvania | 19103 | Not yet recruiting |
| Texas Oncology - Gulf Coast | Beaumont | Texas | 77702 | Recruiting |
| Texas Oncology - San Antonio | Fredericksburg | Texas | 78624 | Recruiting |
| Texas Oncology - Gulf Coast | Houston | Texas | 77024 | Recruiting |
| Texas Oncology - Gulf Coast | Houston | Texas | 77054 | Recruiting |
| Texas Oncology - San Antonio | New Braunfels | Texas | 78130 | Recruiting |
| Texas Oncology - Gulf Coast | Pearland | Texas | 77584 | Recruiting |
| Texas Oncology - San Antonio | San Antonio | Texas | 78217 | Recruiting |
| Texas Oncology - San Antonio | San Antonio | Texas | 78240 | Recruiting |
| Texas Oncology - San Antonio | San Antonio | Texas | 78258 | Recruiting |
| Texas Oncology - Gulf Coast | Sugar Land | Texas | 77479 | Recruiting |
| Texas Oncology - Gulf Coast | The Woodlands | Texas | 77380 | Recruiting |
| Texas Oncology - Gulf Coast | Webster | Texas | 77598 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 12 non-U.S. sites.
Recently updated Small Cell Lung Cancer (SCLC) trials
Other public records listing Small Cell Lung Cancer (SCLC). Sorted by last update posted; newest first. Not a recommendation.
- NCT07795411: Prospective Multiomic Analysis in Small-Cell Lung Cancer Not yet recruiting
- NCT07783477: A Study of Armored CAR T Cells in People With Cancer Not yet recruiting
- NCT07149363: Adjuvant Chemotherapy and Immunotherapy for Completely Resected Small Cell Lung Cancer Recruiting
- NCT07472517: DAREON ® -Lung-1: A Study in People With Advanced Small Cell Lung Cancer to Compare Obrixtamig Plus Atezolizumab, Carboplatin, and Etoposide Treatment With Standard Chemotherapy Recruiting
- NCT07488923: A First-in-human (FIH), Phase 1 Study of ML261, an Autologous Potency Enhanced Anti-DLL3 CAR T Cell Therapy, in Participants With R/R SCLC or Select NECs (SPECTRAL-1) Not yet recruiting
- NCT06736418: Study of 225Ac-ABD147 to Establish Optimal Dose in Patients With SCLC and LCNEC of the Lung That Previously Received Platinum-based Chemotherapy Active, not recruiting
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07226999, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 19, 2026 · Synced May 18, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07226999 live on ClinicalTrials.gov.