A Study to Evaluate the Efficacy and Safety of Belantamab Mafodotin in Combination With Standard of Care in Participants With Relapsed-Refractory Multiple Myeloma (RRMM)
Public ClinicalTrials.gov record NCT07227311. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Multicenter, Open Label, Non-randomized Study to Evaluate the Efficacy and Safety of Extended Dosing of Belantamab Mafodotin in Different Combinations With Standard of Care Regimens in Participants With Relapsed-refractory Multiple Myeloma (DREAMM-15)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study is for adults with multiple myeloma (a type of blood cancer) that has come back after being treated earlier or isn't responding to the current treatment. The main goal is to find out if the study drug, belantamab mafodotin, given less often (on an extended schedule) with other cancer medicines, can still treat the cancer effectively while causing fewer side effects, especially those affecting the eyes. The study will also look at how well the treatment works overall and how safe it is when administered to the participants.
Study identification
- NCT ID
- NCT07227311
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 200 participants
Conditions and interventions
Conditions
Interventions
- Belantamab mafodotin Drug
- Dexamethasone Drug
- Pomalidomide Drug
- Bortezomib Drug
- Carfilzomib Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 14, 2026
- Primary completion
- Aug 29, 2030
- Completion
- Aug 29, 2030
- Last update posted
- Aug 24, 2026
2026 – 2030
United States locations
- U.S. sites
- 12
- U.S. states
- 9
- U.S. cities
- 12
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| GSK Investigational Site | Los Alamitos | California | 90720 | Recruiting |
| GSK Investigational Site | Torrance | California | 90505 | Recruiting |
| GSK Investigational Site | Whittier | California | 90602 | Recruiting |
| GSK Investigational Site | Norwich | Connecticut | 06360 | Recruiting |
| GSK Investigational Site | Fort Myers | Florida | 33912 | Recruiting |
| GSK Investigational Site | Macon | Georgia | 31210 | Recruiting |
| GSK Investigational Site | Baton Rouge | Louisiana | 70809 | Recruiting |
| GSK Investigational Site | Bethesda | Maryland | 20817 | Recruiting |
| GSK Investigational Site | Bridgeton | Missouri | 63044 | Recruiting |
| GSK Investigational Site | Springfield | Missouri | 65807 | Recruiting |
| GSK Investigational Site | Farmington | New Mexico | 87401 | Recruiting |
| GSK Investigational Site | Nashville | Tennessee | 37203 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 47 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07227311, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 24, 2026 · Synced Sep 11, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07227311 live on ClinicalTrials.gov.