A Study of DII235 in Adults With Elevated Lipoprotein(a)
Public ClinicalTrials.gov record NCT07235046. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multi-center, Randomized, Double-blind, Placebo-controlled, Parallel-group, Dose-finding Study to Evaluate Efficacy, Safety, and Tolerability of DII235 in Adults With Elevated Lipoprotein(a)
Study identification
- NCT ID
- NCT07235046
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Novartis Pharmaceuticals
- Industry
- Enrollment
- 200 participants
Conditions and interventions
Conditions
Interventions
- DII235 Drug
- Saline Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 1, 2025
- Primary completion
- Sep 7, 2027
- Completion
- Sep 7, 2028
- Last update posted
- Apr 13, 2026
2025 – 2028
United States locations
- U.S. sites
- 37
- U.S. states
- 18
- U.S. cities
- 36
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Parkway Medical Center | Birmingham | Alabama | 35215 | Recruiting |
| Heart Center Research Llc | Huntsville | Alabama | 35801 | Recruiting |
| Cardiology and Medicine Clinic PA | Little Rock | Arkansas | 72204 | Recruiting |
| National Heart Institute | Beverly Hills | California | 90211 | Recruiting |
| Alliance Clinical | Canoga Park | California | 91303 | Recruiting |
| Excel Medical Clinical Trials LLC | Boca Raton | Florida | 33434 | Recruiting |
| Zenith Clinical Research | Hollywood | Florida | 33021 | Recruiting |
| Jacksonville Center for Clinical Research | Jacksonville | Florida | 32216 | Recruiting |
| Flourish Res Acq LLC North Miami | Miami | Florida | 33138 | Recruiting |
| Inpatient Research Clinical LLC | Miami Lakes | Florida | 33014 | Recruiting |
| Ocala Cardiovascular Research | Ocala | Florida | 34471 | Active, not recruiting |
| SEC Clinical Research | Pensacola | Florida | 32503 | Recruiting |
| Cardiology Partners Clinical Research Institute | Wellington | Florida | 33449 | Recruiting |
| Atlanta Heart Specialists LLC | Tucker | Georgia | 30084 | Recruiting |
| AMR Chicago | Oak Brook | Illinois | 60523 | Recruiting |
| CV Ins of the South | Lafayette | Louisiana | 70503 | Recruiting |
| Monroe Research Llc | West Monroe | Louisiana | 71291 | Recruiting |
| Metropolitan Cardiovascular Consultants Llc | Beltsville | Maryland | 20705 | Recruiting |
| Anderson Medical Research | Ft. Washington | Maryland | 20744 | Recruiting |
| Capitol Cardiology Associates | Lanham | Maryland | 20706 | Recruiting |
| AA Medical Research Center | Flint | Michigan | 48504 | Recruiting |
| Trinity Health Michigan Heart | Ypsilanti | Michigan | 48197 | Recruiting |
| Cardiology Associates of North MS | Tupelo | Mississippi | 38801 | Recruiting |
| AB Clinical Trials | Las Vegas | Nevada | 89119 | Recruiting |
| K and R Research LLC | Marion | Ohio | 43302 | Recruiting |
| TCV Clinical Studies | Linwood | Pennsylvania | 19061 | Active, not recruiting |
| Cardiology Consultants of Philadelphia | Yardley | Pennsylvania | 19067 | Active, not recruiting |
| Apex Cardiology Research Associates of Jackson | Jackson | Tennessee | 38301 | Recruiting |
| Alliance for Multispecialty Research | Knoxville | Tennessee | 37909 | Recruiting |
| Angiocardiac Care of Texas PA | Houston | Texas | 77025 | Recruiting |
| Dallas Heart and Vascular Consultants PA | Houston | Texas | 77084 | Recruiting |
| Biopharma Informatic | Katy | Texas | 77479 | Recruiting |
| Clinical Trials of Texas | San Antonio | Texas | 78229 | Recruiting |
| Northwest Houston Clinical Research PLLC | Tomball | Texas | 77375 | Recruiting |
| Progressive Clinical Research | Bountiful | Utah | 84010 | Recruiting |
| Dominion Medical Associates | Richmond | Virginia | 23219 | Recruiting |
| MultiCare Ins Research Innovation | Puyallup | Washington | 98372 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 28 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07235046, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 13, 2026 · Synced May 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07235046 live on ClinicalTrials.gov.