Phase 2A/B Efficacy and Safety of Dabogratinib in Participants With Low Grade Upper Tract Urothelial Carcinoma
Public ClinicalTrials.gov record NCT07265947. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2A/B, Multi-center, Open-Label Study Evaluating the Efficacy and Safety of Dabogratinib (TYRA-300) in Participants With Low Grade Upper Tract Urothelial Carcinoma (SURF303)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
A Phase 2A/B study of Dabogratinib (TYRA-300) in Low Grade Upper Tract Urothelial Carcinoma
Study identification
- NCT ID
- NCT07265947
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 285 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 22, 2025 (Actual)
- Primary completion
- Oct 2030 (Estimated)
- Completion
- Nov 2030 (Estimated)
- Last update posted
- Oct 16, 2026
2025 – 2030
United States locations
- U.S. sites
- 23
- U.S. states
- 15
- U.S. cities
- 23
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Loma Linda University (LLU) - Loma Linda University Medical Center (LLUM) | Loma Linda | California | 92354-3450 | Recruiting |
| USC Norris Comprehensive Cancer Center | Los Angeles | California | 90033 | Recruiting |
| Moffitt Cancer Center | Tampa | Florida | 33612-9416 | Recruiting |
| The Winship Cancer Institute of Emory University | Atlanta | Georgia | 30322-1013 | Recruiting |
| Duly Health and Care Chicago | Lisle | Illinois | 60532 | Recruiting |
| Urology of Indiana, LLC | Greenwood | Indiana | 46143 | Recruiting |
| Indiana University (IU) Health Physicians - Urology | Indianapolis | Indiana | 46202 | Recruiting |
| First Urology | Jeffersonville | Indiana | 47130 | Recruiting |
| Greater Boston Urology - Plymouth Care Center | Plymouth | Massachusetts | 02360 | Recruiting |
| University of Michigan Health System (UMHS) | Ann Arbor | Michigan | 48109-5000 | Recruiting |
| Michigan Healthcare Professionals - William Beaumont University Hospital | Royal Oak | Michigan | 48073-0996 | Recruiting |
| Urology of St. Louis | St Louis | Missouri | 63141 | Recruiting |
| Summit Health - Washington Township | Sewell | New Jersey | 08080-2359 | Recruiting |
| Albany Medical College | Albany | New York | 12208-3412 | Recruiting |
| Associated Medical Professionals of NY, PLLC | Syracuse | New York | 13210 | Recruiting |
| Cleveland Clinic | Cleveland | Ohio | 44111 | Recruiting |
| Central Ohio Urology Group | Gahanna | Ohio | 43230 | Recruiting |
| Penn Medicine Radnor | Radnor | Pennsylvania | 19087 | Recruiting |
| Medical University of South Carolina (MUSC) | Mt. Pleasant | South Carolina | 29464-3771 | Recruiting |
| Urology Associates, P C | Nashville | Tennessee | 37209-4035 | Recruiting |
| Urology Austin - Apex Cancer Care - Austin | Austin | Texas | 78705-2009 | Recruiting |
| The University of Texas Southwestern Medical Center | Dallas | Texas | 75235 | Recruiting |
| The University of Texas MD Anderson Cancer Center | Houston | Texas | 77030 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 9 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07265947, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 16, 2026 · Synced Oct 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT07265947 live on ClinicalTrials.gov.