A Study to Investigate Efficacy, Safety and Tolerability of Barzolvolimab Versus Placebo in Adults With Cold Induced Urticaria and Symptomatic Dermographism Inadequately Controlled by H1-antihistamines (EMBARQ - ColdU and SD)
Public ClinicalTrials.gov record NCT07266402. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3 Randomized, Double-Blind, Placebo-Controlled, Multi-Center, Parallel-Group Study of Barzolvolimab in Participants With Cold Induced Urticaria and Symptomatic Dermographism (EMBARQ-COLDU and SD)
Study identification
- NCT ID
- NCT07266402
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Celldex Therapeutics
- Industry
- Enrollment
- 240 participants
Conditions and interventions
Conditions
Interventions
- Barzolvolimab Drug
- Matching Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 14, 2026
- Primary completion
- May 31, 2028
- Completion
- Sep 30, 2028
- Last update posted
- May 7, 2026
2026 – 2028
United States locations
- U.S. sites
- 26
- U.S. states
- 16
- U.S. cities
- 25
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Cahaba Dermatology & Skin Health Center, LLC | Birmingham | Alabama | 35244 | Recruiting |
| One of a Kind Clinical Research Center, LLC | Scottsdale | Arizona | 85258 | Recruiting |
| Kern Research, Inc. | Bakersfield | California | 93301 | Recruiting |
| One of a Kind Clinical Research Center | Napa | California | 94558 | Recruiting |
| Allergy & Asthma Consultants | Redwood City | California | 94063 | Recruiting |
| Amicis Research Center | Sherman Oaks | California | 91403 | Recruiting |
| FOMAT - Allergy, Asthma & Immunology Medical Group | Ventura | California | 93003 | Recruiting |
| Direct Helpers Research Center | Hialeah | Florida | 33012 | Recruiting |
| Well Pharma Medical Research, Corp. | Miami | Florida | 33143 | Recruiting |
| Deluxe Health Center, LLC | Miami Lakes | Florida | 33014 | Recruiting |
| GCP, Global Clinical Professionals | St. Petersburg | Florida | 33705 | Recruiting |
| Advanced Clinical Research Institute | Tampa | Florida | 33607 | Recruiting |
| Centricity Research Columbus Dermatology | Columbus | Georgia | 31904 | Recruiting |
| Treasure Valley Medical Research | Boise | Idaho | 83706 | Recruiting |
| Endeavor Health Clinical Trials Center | Skokie | Illinois | 60077 | Recruiting |
| Equity Medical, LLC | Bowling Green | Kentucky | 42104 | Recruiting |
| Advanced ENT and Allergy, PLLC | Louisville | Kentucky | 40207 | Recruiting |
| Johns Hopkins University | Baltimore | Maryland | 21224 | Recruiting |
| Revival Research Institute, LLC | Troy | Michigan | 48084 | Recruiting |
| Equity Medical, LLC | New York | New York | 10023 | Recruiting |
| Markowitz Medical PLLC dba OptiSkin Medical | New York | New York | 10128 | Recruiting |
| University of Cincinnati | Cincinnati | Ohio | 45267 | Not yet recruiting |
| Allergy, Asthma & Clinical Research Center | Oklahoma City | Oklahoma | 73120 | Recruiting |
| Advanced Dermatology and Cosmetic Surgery - Spartanburg | Spartanburg | South Carolina | 29307 | Recruiting |
| RFSA Dermatology | San Antonio | Texas | 78212 | Recruiting |
| Allergy Associates of Utah | Sandy City | Utah | 84093 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 46 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07266402, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 7, 2026 · Synced May 19, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07266402 live on ClinicalTrials.gov.