ClinicalTrials.gov record
A Study to Evaluate the Efficacy and Safety of mRNA-1283 and mRNA-1273 in Participants 50 to 64 Years of Age Without High-Risk Conditions for Severe Coronavirus Disease 2019 (COVID-19)
ClinicalTrials.gov ID: NCT07266558
Public ClinicalTrials.gov record NCT07266558. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
ClinicalTrials.gov public records Last synced May 6, 2026, 8:10 PM EDT
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 4, Randomized, Observer-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of mRNA-1283 And mRNA-1273 Variant-Containing Formulation in Adults 50 to 64 Years of Age Without Underlying Conditions That Put Them at High Risk for Severe Outcomes From COVID-19
Study identification
- NCT ID
- NCT07266558
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 4
- Lead sponsor
- ModernaTX, Inc.
- Industry
- Enrollment
- 30,000 participants
Conditions and interventions
Conditions
Interventions
- Placebo Biological
- mRNA-1273 Biological
- mRNA-1283 Biological
Biological
Eligibility (public fields only)
- Age range
- 50 Years to 64 Years
- Sex
- All
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 25, 2025
- Primary completion
- Jun 15, 2027
- Completion
- Jun 15, 2027
- Last update posted
- Apr 27, 2026
2025 – 2027
United States locations
- U.S. sites
- 150
- U.S. states
- 38
- U.S. cities
- 130
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Accel Clinical Research | Birmingham | Alabama | 35216 | — |
| Cullman Clinical Trials | Cullman | Alabama | 35055 | — |
| AMR Clinical Mobile | Mobile | Alabama | 36608 | — |
| Velocity Clinical Research, Mobile | Mobile | Alabama | 36608 | — |
| Lenzmeier Family Medicine - Avacare | Glendale | Arizona | 85308 | — |
| Desert Clinical Research | Mesa | Arizona | 85213 | — |
| Velocity Clinical Research - Phoenix | Phoenix | Arizona | 85006 | — |
| Foothills Research Center/Avacare | Phoenix | Arizona | 85044 | — |
| Headlands Research Scottsdale | Scottsdale | Arizona | 85260 | — |
| Fiel Family and Sports Medicine / Avacare | Tempe | Arizona | 85283 | — |
| Avacare | Colton | California | 92324 | — |
| CenExel CNR | Garden Grove | California | 92845 | — |
| Velocity Clinical Research, Huntington Park | Huntington Park | California | 90255 | — |
| Velocity Clinical Research - San Diego - ERN - PPDS-Site Number:8400010 | La Mesa | California | 91942 | — |
| Velocity Clinical Research - Los Angeles | Los Angeles | California | 90017 | — |
| Artemis Institute for Clinical Research | Riverside | California | 92503 | — |
| Peninsula Research Associates | Rolling Hills Estates | California | 90274 | — |
| Velocity Clinical Research -- Banning | San Bernardino | California | 92408 | — |
| Artemis Institute for Clinical Research | San Diego | California | 92103 | — |
| Tekton Research, LLC | Denver | Colorado | 80238 | — |
| Tekton Research, LLC | Fort Collins | Colorado | 80525 | — |
| Critical Care, Pulmonary and Sleep Associates, P.LLP/Avacare | Lakewood | Colorado | 80228 | — |
| Tekton Research, LLC | Longmont | Colorado | 80501 | — |
| New England Research Associates | Bridgeport | Connecticut | 06606 | — |
| Stamford Therapeutics Consortium | Stamford | Connecticut | 06905 | — |
| Velocity Clinical Research-Washington, DC | Washington D.C. | District of Columbia | 20016 | — |
| Hillcrest Medical Research, LLC | DeLand | Florida | 32720 | — |
| University Clinical Research-Deland, LLC d/b/a Accel Research Sites - Deland Clinical Research Unit | DeLand | Florida | 32720 | — |
| Suncoast Research Associates, LLC | Doral | Florida | 33172 | — |
| Velocity Clinical Research, Hallandale Beach | Hallandale | Florida | 33009 | — |
| Indago Research & Health Center, Inc | Hialeah | Florida | 33012 | — |
| CenExel Research Centers of America | Hollywood | Florida | 33024 | — |
| NextPhase Research Florida | Hollywood | Florida | 33024 | — |
| Health Awareness Inc. | Jupiter | Florida | 33458 | — |
| Sandhill Research, LLC d/b/a Accel Research Sites - Lakeland Clinical Research Unit | Lakeland | Florida | 33803 | — |
| Sandhill Research, LLC d/b/a Accel Research Sites- St. Pete-Largo Clinical Research Unit | Largo | Florida | 33777 | — |
| Accel Research Sites | Maitland | Florida | 32751 | — |
| Global Health Research Center, Inc. | Miami Lakes | Florida | 33016 | — |
| Suncoast Clinical Research | New Port Richey | Florida | 34652 | — |
| Headlands Research Orlando | Orlando | Florida | 32819 | — |
| Innovation Medical Research Center | Palmetto Bay | Florida | 33157 | — |
| ForCare Clinical Research | Tampa | Florida | 33613 | — |
| Global Health Research Center, Inc. | Tampa | Florida | 33615 | — |
| Javara Inc. and PRIVIA Medical Group of Georgia, LLC | Albany | Georgia | 31707 | — |
| DelRicht Research | Atlanta | Georgia | 30329 | — |
| Atlanta Center for Medical Research | Atlanta | Georgia | 30331 | — |
| Accel Research Sites - Neurostudies | Decatur | Georgia | 30030 | — |
| CenExel iResearch, LLC | Decatur | Georgia | 30030 | — |
| Javara Inc. and Privia Medical Group of Georgia, LLC | Fayetteville | Georgia | 30214 | — |
| Velocity Clinical Research Savannah | Savannah | Georgia | 31406 | — |
| Clinical Research Atlanta | Stockbridge | Georgia | 30281 | — |
| Velocity Clinical Research - Boise - ERN - PPDS | Meridian | Idaho | 83642 | — |
| DM Clinical Research - Melrose Park | Melrose Park | Illinois | 60160 | — |
| Velocity Clinical Research Valparaiso | Valparaiso | Indiana | 46383 | — |
| Velocity Clinical Research - Sioux City | Sioux City | Iowa | 51106 | — |
| Johnson County Clin-Trials | Lenexa | Kansas | 66212 | — |
| Tekton Research, LLC | Wichita | Kansas | 67218 | — |
| DelRicht Research | Louisville | Kentucky | 40205 | — |
| Versailles Family Medicine - CCT Research | Versailles | Kentucky | 40383 | — |
| Velocity Clinical Research-Baton Rouge | Baton Rouge | Louisiana | 70809 | — |
| Velocity Clinical Research - Covington | Covington | Louisiana | 70433 | — |
| Avacare | Kenner | Louisiana | 70065 | — |
| Velocity Clinical Research, Lafayette | Lafayette | Louisiana | 70508 | — |
| DelRicht Research | Mandeville | Louisiana | 70471 | — |
| DelRicht Research | New Orleans | Louisiana | 70115 | — |
| Velocity Clinical Research, New Orleans | New Orleans | Louisiana | 70119 | — |
| DelRicht Research | Prairieville | Louisiana | 70769 | — |
| Annapolis Internal Medicine | Annapolis | Maryland | 21401 | — |
| Centennial Medical Group | Columbia | Maryland | 21045 | — |
| Velocity Clinical Research, Rockville | Rockville | Maryland | 20854 | — |
| Brigham and Women's Hospital | Boston | Massachusetts | 02115 | — |
| DM Clinical Research - Brookline | Brookline | Massachusetts | 02446 | — |
| ActivMed Practices & Research, LLC | Methuen | Massachusetts | 01844 | — |
| Headlands Research Detroit | Southfield | Michigan | 48034 | — |
| DM Clinical Research - Southfield | Southfield | Michigan | 48076 | — |
| Javara Inc. and Mankato Clinic, Ltd. | Mankato | Minnesota | 56001 | — |
| Velocity Clinical Research Gulfport | Gulfport | Mississippi | 39503 | — |
| Clinical Research Professionals | Chesterfield | Missouri | 63005 | — |
| AMR Clinical | Kansas City | Missouri | 64116 | — |
| Clay-Platte Family Medicine Clinic | Kansas City | Missouri | 64151 | — |
| DelRicht Research | Springfield | Missouri | 65807 | — |
| Sundance Clinical Research, LLC | St Louis | Missouri | 63141 | — |
| DelRicht Research | Town and Country | Missouri | 63017 | — |
| Avacare Research/Methodist Physicians Clinic | Fremont | Nebraska | 68025 | — |
| Velocity Clinical Research, Grand Island | Grand Island | Nebraska | 68803 | — |
| Velocity Clinical Research | Lincoln | Nebraska | 68510 | — |
| Velocity Clinical Research Norfolk | Norfolk | Nebraska | 68701 | — |
| Velocity Clinical Research Omaha | Omaha | Nebraska | 68134 | — |
| Avacare/Midwest Regional Health Services | Omaha | Nebraska | 68144 | — |
| Papillion Research/Avacare | Papillion | Nebraska | 68046 | — |
| Santa Rosa Medical Centers of Nevada | Las Vegas | Nevada | 89119 | — |
| DM Clinical Research - Jersey City | Jersey City | New Jersey | 07306 | — |
| DM Clinical Research - Albuquerque | Albuquerque | New Mexico | 87106 | — |
| Velocity Clinical Research - Albuquerque | Albuquerque | New Mexico | 87107 | — |
| Rochester Clinical Research | Rochester | New York | 14609 | — |
| Velocity Clinical Research, Durham | Durham | North Carolina | 27701 | — |
| Eximia Research - NC, LLC | Raleigh | North Carolina | 27607 | — |
| TMA Headlands LLC d/b/a Trial Management Associates | Wilmington | North Carolina | 28403 | — |
| Wake Forest University Health Sciences | Winston-Salem | North Carolina | 27157 | — |
| Velocity Clinical Research - Cleveland | Beachwood | Ohio | 44122 | — |
| CTI Clinical Research Center | Cincinnati | Ohio | 45212 | — |
| Velocity Clinical Research-Mt. Auburn | Cincinnati | Ohio | 45242 | — |
| Velocity Clinical Research Springdale | Cincinnati | Ohio | 45246 | — |
| Tekton Research, LLC | Edmond | Oklahoma | 73013 | — |
| Tekton Research, LLC | Moore | Oklahoma | 73160 | — |
| DelRicht Research | Tulsa | Oklahoma | 74133 | — |
| Tekton Research, LLC | Yukon | Oklahoma | 73099 | — |
| Velocity Clinical Research - Medford | Medford | Oregon | 97504 | — |
| Summit Headlands LLC | Portland | Oregon | 97210 | — |
| Hatboro Medical Associates/Avacare | Horsham | Pennsylvania | 19044 | — |
| DM Clinical Research - Philadelphia | Philadelphia | Pennsylvania | 19107 | — |
| Velocity Clinical Research - East Greenwich | East Greenwich | Rhode Island | 02818 | — |
| Velocity Clinical Research, Anderson | Anderson | South Carolina | 29621 | — |
| DelRicht Research | Charleston | South Carolina | 29407 | — |
| Velocity Clinical Research - Columbia | Columbia | South Carolina | 29204 | — |
| Coastal Carolina Research Center, LLC | North Charleston | South Carolina | 29405 | — |
| Velocity Clinical Research Spartanburg | Spartanburg | South Carolina | 29303 | — |
| Velocity Clinical Research Union | Union | South Carolina | 29379 | — |
| DelRicht Research | Hendersonville | Tennessee | 37075 | — |
| Velocity Clinical Research, Abilene | Abilene | Texas | 79606 | — |
| Tekton Research, LLC | Austin | Texas | 78745 | — |
| Velocity Clinical Research - Austin | Austin | Texas | 78759 | — |
| Tekton Research, LLC | Beaumont | Texas | 77706 | — |
| Javara Inc. and Privia Medical Group Gulf Coast, PLLC | Conroe | Texas | 77384 | — |
| Velocity Clinical Research - Dallas | Dallas | Texas | 75230 | — |
| Avacare | Fort Worth | Texas | 76135 | — |
| DM Clinical Research - Houston | Houston | Texas | 77065 | — |
| DM Clinical Research - Houston | Houston | Texas | 77081 | — |
| DelRicht Research | Prosper | Texas | 75078 | — |
| Be Well Clinical Studies | Round Rock | Texas | 78681 | — |
| DM Clinical Research - San Antonio | San Antonio | Texas | 78207 | — |
| Tekton Research, LLC | San Antonio | Texas | 78229 | — |
| Javara Inc. and Privia Medical Group Gulf Coast, PLLC | San Marcos | Texas | 78666 | — |
| Javara Inc. and Privia Medical Group - North Texas | Stephenville | Texas | 76401 | — |
| DM Clinical Research - Sugar Land | Sugar Land | Texas | 77478 | — |
| Javara Inc. and Privia Medical Group Gulf Coast, PLLC | Sugar Land | Texas | 77478 | — |
| Olympus Clinical Research | Sugar Land | Texas | 77479 | — |
| DM Clinical Research - Tomball | Tomball | Texas | 77375 | — |
| Cope Family Medicine / Avacare | Bountiful | Utah | 84010 | — |
| Mountain View/Avacare | Pleasant View | Utah | 84404 | — |
| JBR Clinical Research | Salt Lake City | Utah | 84107 | — |
| Olympus Family Medicine/Avacare | Salt Lake City | Utah | 84117 | — |
| J. Lewis Research, Inc/Jordan River Family Medicine | South Jordan | Utah | 84095 | — |
| South Ogden Family Medicine/ Avacare | South Ogden | Utah | 84405 | — |
| Velocity Clinical Research - Salt Lake City (West Jordan) | West Jordan | Utah | 84088 | — |
| Charlottesville Medical Research, LLC | Charlottesville | Virginia | 22911 | — |
| Velocity Clinical Research-Hampton | Hampton | Virginia | 23666 | — |
| Clinical Research Partners, LLC | Richmond | Virginia | 23226 | — |
| Velocity Clinical Research - Suffolk | Suffolk | Virginia | 23435 | — |
| Velocity Clinical Research, Spokane | Spokane | Washington | 99218 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07266558, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 27, 2026 · Synced May 6, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07266558 live on ClinicalTrials.gov.