ClinicalTrials.gov record
A Study to Evaluate the Efficacy and Safety of mRNA-1283 and mRNA-1273 in Participants 50 to 64 Years of Age Without High-Risk Conditions for Severe Coronavirus Disease 2019 (COVID-19)
ClinicalTrials.gov ID: NCT07266558
Public ClinicalTrials.gov record NCT07266558. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 4, Randomized, Observer-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of mRNA-1283 And mRNA-1273 Variant-Containing Formulation in Adults 50 to 64 Years of Age Without Underlying Conditions That Put Them at High Risk for Severe Outcomes From COVID-19
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to evaluate the efficacy and safety of mRNA-1283 and mRNA-1273 (variant formulations) in adults 50 to 64 years of age without high risk factors for severe COVID-19.
Study identification
- NCT ID
- NCT07266558
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 4
- Enrollment
- 30,000 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 50 Years to 64 Years
- Sex
- All
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 26, 2025 (Actual)
- Primary completion
- Jun 16, 2027 (Estimated)
- Completion
- Jun 16, 2027 (Estimated)
- Last update posted
- Sep 28, 2026
2025 – 2027
United States locations
- U.S. sites
- 150
- U.S. states
- 38
- U.S. cities
- 130
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Accel Clinical Research | Birmingham | Alabama | 35216 | — |
| Cullman Clinical Trials | Cullman | Alabama | 35055 | — |
| AMR Clinical Mobile | Mobile | Alabama | 36608 | — |
| Velocity Clinical Research, Mobile | Mobile | Alabama | 36608 | — |
| Lenzmeier Family Medicine - Avacare | Glendale | Arizona | 85308 | — |
| Desert Clinical Research | Mesa | Arizona | 85213 | — |
| Velocity Clinical Research - Phoenix | Phoenix | Arizona | 85006 | — |
| Foothills Research Center/Avacare | Phoenix | Arizona | 85044 | — |
| Headlands Research Scottsdale | Scottsdale | Arizona | 85260 | — |
| Fiel Family and Sports Medicine / Avacare | Tempe | Arizona | 85283 | — |
| Avacare | Colton | California | 92324 | — |
| CenExel CNR | Garden Grove | California | 92845 | — |
| Velocity Clinical Research, Huntington Park | Huntington Park | California | 90255 | — |
| Velocity Clinical Research - San Diego - ERN - PPDS-Site Number:8400010 | La Mesa | California | 91942 | — |
| Velocity Clinical Research - Los Angeles | Los Angeles | California | 90017 | — |
| Artemis Institute for Clinical Research | Riverside | California | 92503 | — |
| Peninsula Research Associates | Rolling Hills Estates | California | 90274 | — |
| Velocity Clinical Research -- Banning | San Bernardino | California | 92408 | — |
| Artemis Institute for Clinical Research | San Diego | California | 92103 | — |
| Tekton Research, LLC | Denver | Colorado | 80238 | — |
| Tekton Research, LLC | Fort Collins | Colorado | 80525 | — |
| Critical Care, Pulmonary and Sleep Associates, P.LLP/Avacare | Lakewood | Colorado | 80228 | — |
| Tekton Research, LLC | Longmont | Colorado | 80501 | — |
| New England Research Associates | Bridgeport | Connecticut | 06606 | — |
| Stamford Therapeutics Consortium | Stamford | Connecticut | 06905 | — |
| Velocity Clinical Research-Washington, DC | Washington D.C. | District of Columbia | 20016 | — |
| Hillcrest Medical Research, LLC | DeLand | Florida | 32720 | — |
| University Clinical Research-Deland, LLC d/b/a Accel Research Sites - Deland Clinical Research Unit | DeLand | Florida | 32720 | — |
| Suncoast Research Associates, LLC | Doral | Florida | 33172 | — |
| Velocity Clinical Research, Hallandale Beach | Hallandale | Florida | 33009 | — |
| Indago Research & Health Center, Inc | Hialeah | Florida | 33012 | — |
| CenExel Research Centers of America | Hollywood | Florida | 33024 | — |
| NextPhase Research Florida | Hollywood | Florida | 33024 | — |
| Health Awareness Inc. | Jupiter | Florida | 33458 | — |
| Sandhill Research, LLC d/b/a Accel Research Sites - Lakeland Clinical Research Unit | Lakeland | Florida | 33803 | — |
| Sandhill Research, LLC d/b/a Accel Research Sites- St. Pete-Largo Clinical Research Unit | Largo | Florida | 33777 | — |
| Accel Research Sites | Maitland | Florida | 32751 | — |
| Global Health Research Center, Inc. | Miami Lakes | Florida | 33016 | — |
| Suncoast Clinical Research | New Port Richey | Florida | 34652 | — |
| Headlands Research Orlando | Orlando | Florida | 32819 | — |
| Innovation Medical Research Center | Palmetto Bay | Florida | 33157 | — |
| ForCare Clinical Research | Tampa | Florida | 33613 | — |
| Global Health Research Center, Inc. | Tampa | Florida | 33615 | — |
| Javara Inc. and PRIVIA Medical Group of Georgia, LLC | Albany | Georgia | 31707 | — |
| DelRicht Research | Atlanta | Georgia | 30329 | — |
| Atlanta Center for Medical Research | Atlanta | Georgia | 30331 | — |
| Accel Research Sites - Neurostudies | Decatur | Georgia | 30030 | — |
| CenExel iResearch, LLC | Decatur | Georgia | 30030 | — |
| Javara Inc. and Privia Medical Group of Georgia, LLC | Fayetteville | Georgia | 30214 | — |
| Velocity Clinical Research Savannah | Savannah | Georgia | 31406 | — |
| Clinical Research Atlanta | Stockbridge | Georgia | 30281 | — |
| Velocity Clinical Research - Boise - ERN - PPDS | Meridian | Idaho | 83642 | — |
| DM Clinical Research - Melrose Park | Melrose Park | Illinois | 60160 | — |
| Velocity Clinical Research Valparaiso | Valparaiso | Indiana | 46383 | — |
| Velocity Clinical Research - Sioux City | Sioux City | Iowa | 51106 | — |
| Johnson County Clin-Trials | Lenexa | Kansas | 66212 | — |
| Tekton Research, LLC | Wichita | Kansas | 67218 | — |
| DelRicht Research | Louisville | Kentucky | 40205 | — |
| Versailles Family Medicine - CCT Research | Versailles | Kentucky | 40383 | — |
| Velocity Clinical Research-Baton Rouge | Baton Rouge | Louisiana | 70809 | — |
| Velocity Clinical Research - Covington | Covington | Louisiana | 70433 | — |
| Avacare | Kenner | Louisiana | 70065 | — |
| Velocity Clinical Research, Lafayette | Lafayette | Louisiana | 70508 | — |
| DelRicht Research | Mandeville | Louisiana | 70471 | — |
| DelRicht Research | New Orleans | Louisiana | 70115 | — |
| Velocity Clinical Research, New Orleans | New Orleans | Louisiana | 70119 | — |
| DelRicht Research | Prairieville | Louisiana | 70769 | — |
| Annapolis Internal Medicine | Annapolis | Maryland | 21401 | — |
| Centennial Medical Group | Columbia | Maryland | 21045 | — |
| Velocity Clinical Research, Rockville | Rockville | Maryland | 20854 | — |
| Brigham and Women's Hospital | Boston | Massachusetts | 02115 | — |
| DM Clinical Research - Brookline | Brookline | Massachusetts | 02446 | — |
| ActivMed Practices & Research, LLC | Methuen | Massachusetts | 01844 | — |
| Headlands Research Detroit | Southfield | Michigan | 48034 | — |
| DM Clinical Research - Southfield | Southfield | Michigan | 48076 | — |
| Javara Inc. and Mankato Clinic, Ltd. | Mankato | Minnesota | 56001 | — |
| Velocity Clinical Research Gulfport | Gulfport | Mississippi | 39503 | — |
| Clinical Research Professionals | Chesterfield | Missouri | 63005 | — |
| AMR Clinical | Kansas City | Missouri | 64116 | — |
| Clay-Platte Family Medicine Clinic | Kansas City | Missouri | 64151 | — |
| DelRicht Research | Springfield | Missouri | 65807 | — |
| Sundance Clinical Research, LLC | St Louis | Missouri | 63141 | — |
| DelRicht Research | Town and Country | Missouri | 63017 | — |
| Avacare Research/Methodist Physicians Clinic | Fremont | Nebraska | 68025 | — |
| Velocity Clinical Research, Grand Island | Grand Island | Nebraska | 68803 | — |
| Velocity Clinical Research | Lincoln | Nebraska | 68510 | — |
| Velocity Clinical Research Norfolk | Norfolk | Nebraska | 68701 | — |
| Velocity Clinical Research Omaha | Omaha | Nebraska | 68134 | — |
| Avacare/Midwest Regional Health Services | Omaha | Nebraska | 68144 | — |
| Papillion Research/Avacare | Papillion | Nebraska | 68046 | — |
| Santa Rosa Medical Centers of Nevada | Las Vegas | Nevada | 89119 | — |
| DM Clinical Research - Jersey City | Jersey City | New Jersey | 07306 | — |
| DM Clinical Research - Albuquerque | Albuquerque | New Mexico | 87106 | — |
| Velocity Clinical Research - Albuquerque | Albuquerque | New Mexico | 87107 | — |
| Rochester Clinical Research | Rochester | New York | 14609 | — |
| Velocity Clinical Research, Durham | Durham | North Carolina | 27701 | — |
| Eximia Research - NC, LLC | Raleigh | North Carolina | 27607 | — |
| TMA Headlands LLC d/b/a Trial Management Associates | Wilmington | North Carolina | 28403 | — |
| Wake Forest University Health Sciences | Winston-Salem | North Carolina | 27157 | — |
| Velocity Clinical Research - Cleveland | Beachwood | Ohio | 44122 | — |
| CTI Clinical Research Center | Cincinnati | Ohio | 45212 | — |
| Velocity Clinical Research-Mt. Auburn | Cincinnati | Ohio | 45242 | — |
| Velocity Clinical Research Springdale | Cincinnati | Ohio | 45246 | — |
| Tekton Research, LLC | Edmond | Oklahoma | 73013 | — |
| Tekton Research, LLC | Moore | Oklahoma | 73160 | — |
| DelRicht Research | Tulsa | Oklahoma | 74133 | — |
| Tekton Research, LLC | Yukon | Oklahoma | 73099 | — |
| Velocity Clinical Research - Medford | Medford | Oregon | 97504 | — |
| Summit Headlands LLC | Portland | Oregon | 97210 | — |
| Hatboro Medical Associates/Avacare | Horsham | Pennsylvania | 19044 | — |
| DM Clinical Research - Philadelphia | Philadelphia | Pennsylvania | 19107 | — |
| Velocity Clinical Research - East Greenwich | East Greenwich | Rhode Island | 02818 | — |
| Velocity Clinical Research, Anderson | Anderson | South Carolina | 29621 | — |
| DelRicht Research | Charleston | South Carolina | 29407 | — |
| Velocity Clinical Research - Columbia | Columbia | South Carolina | 29204 | — |
| Coastal Carolina Research Center, LLC | North Charleston | South Carolina | 29405 | — |
| Velocity Clinical Research Spartanburg | Spartanburg | South Carolina | 29303 | — |
| Velocity Clinical Research Union | Union | South Carolina | 29379 | — |
| DelRicht Research | Hendersonville | Tennessee | 37075 | — |
| Velocity Clinical Research, Abilene | Abilene | Texas | 79606 | — |
| Tekton Research, LLC | Austin | Texas | 78745 | — |
| Velocity Clinical Research - Austin | Austin | Texas | 78759 | — |
| Tekton Research, LLC | Beaumont | Texas | 77706 | — |
| Javara Inc. and Privia Medical Group Gulf Coast, PLLC | Conroe | Texas | 77384 | — |
| Velocity Clinical Research - Dallas | Dallas | Texas | 75230 | — |
| Avacare | Fort Worth | Texas | 76135 | — |
| DM Clinical Research - Houston | Houston | Texas | 77065 | — |
| DM Clinical Research - Houston | Houston | Texas | 77081 | — |
| DelRicht Research | Prosper | Texas | 75078 | — |
| Be Well Clinical Studies | Round Rock | Texas | 78681 | — |
| DM Clinical Research - San Antonio | San Antonio | Texas | 78207 | — |
| Tekton Research, LLC | San Antonio | Texas | 78229 | — |
| Javara Inc. and Privia Medical Group Gulf Coast, PLLC | San Marcos | Texas | 78666 | — |
| Javara Inc. and Privia Medical Group - North Texas | Stephenville | Texas | 76401 | — |
| DM Clinical Research - Sugar Land | Sugar Land | Texas | 77478 | — |
| Javara Inc. and Privia Medical Group Gulf Coast, PLLC | Sugar Land | Texas | 77478 | — |
| Olympus Clinical Research | Sugar Land | Texas | 77479 | — |
| DM Clinical Research - Tomball | Tomball | Texas | 77375 | — |
| Cope Family Medicine / Avacare | Bountiful | Utah | 84010 | — |
| Mountain View/Avacare | Pleasant View | Utah | 84404 | — |
| JBR Clinical Research | Salt Lake City | Utah | 84107 | — |
| Olympus Family Medicine/Avacare | Salt Lake City | Utah | 84117 | — |
| J. Lewis Research, Inc/Jordan River Family Medicine | South Jordan | Utah | 84095 | — |
| South Ogden Family Medicine/ Avacare | South Ogden | Utah | 84405 | — |
| Velocity Clinical Research - Salt Lake City (West Jordan) | West Jordan | Utah | 84088 | — |
| Charlottesville Medical Research, LLC | Charlottesville | Virginia | 22911 | — |
| Velocity Clinical Research-Hampton | Hampton | Virginia | 23666 | — |
| Clinical Research Partners, LLC | Richmond | Virginia | 23226 | — |
| Velocity Clinical Research - Suffolk | Suffolk | Virginia | 23435 | — |
| Velocity Clinical Research, Spokane | Spokane | Washington | 99218 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07266558, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 28, 2026 · Synced Oct 23, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT07266558 live on ClinicalTrials.gov.