A Study of Solbinsiran (LY3561774) in Participants With Severe Hypertriglyceridemia
Public ClinicalTrials.gov record NCT07269210. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study to Investigate the Efficacy and Safety of LY3561774 (Solbinsiran) in Adults With Severe Hypertriglyceridemia
Study identification
- NCT ID
- NCT07269210
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Eli Lilly and Company
- Industry
- Enrollment
- 60 participants
Conditions and interventions
Conditions
Interventions
- Placebo Drug
- Solbinsiran Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 7, 2025
- Primary completion
- Feb 28, 2027
- Completion
- Jul 31, 2027
- Last update posted
- Apr 21, 2026
2025 – 2027
United States locations
- U.S. sites
- 29
- U.S. states
- 15
- U.S. cities
- 27
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Axsendo Clinical Research - Peak Heart & Vascular - Phoenix | Phoenix | Arizona | 85014 | Recruiting |
| Synexus Clinical Research US, Inc./Orange Grove Family Practice | Tucson | Arizona | 85741 | Recruiting |
| National Heart Institute | Beverly Hills | California | 90211 | Recruiting |
| Ark Clinical Research | Long Beach | California | 90815 | Recruiting |
| Catalina Research Institute, LLC | Montclair | California | 91763 | Recruiting |
| Valley Clinical Trials, Inc. | Northridge | California | 91325 | Recruiting |
| CMR of Greater New Haven, LLC | Hamden | Connecticut | 06517 | Recruiting |
| Northeast Research Institute - Downtown Office | Jacksonville | Florida | 32204 | Recruiting |
| Novera Clinical Research | Miami | Florida | 33135 | Recruiting |
| Inpatient Research Clinic | Miami Lakes | Florida | 33014 | Recruiting |
| Clinical Site Partners, LLC dba Flourish Research | Winter Park | Florida | 32789 | Recruiting |
| Great Lakes Clinical Trials - Ravenswood | Chicago | Illinois | 60640 | Recruiting |
| Investigators Research Group | Brownsburg | Indiana | 46112 | Recruiting |
| Saint Elizabeth Healthcare - Saint Elizabeth Covington Hospital | Covington | Kentucky | 41011 | Recruiting |
| Flourish Research - Bowie | Bowie | Maryland | 20715 | Recruiting |
| University of Massachusetts Chan Medical School | Worcester | Massachusetts | 01655 | Recruiting |
| AB Clinical Trials | Las Vegas | Nevada | 89119 | Recruiting |
| Clinical Research of Philadelphia | Pennington | New Jersey | 08534 | Recruiting |
| Weill Cornell Medical College | New York | New York | 10021 | Recruiting |
| Icahn School of Medicine at Mount Sinai | New York | New York | 10029 | Recruiting |
| Cardiovascular Specialists of Willowbrook | Houston | Texas | 77070 | Recruiting |
| Southern Endocrinology Associates | Mesquite | Texas | 75149 | Recruiting |
| American Research Corporation at Texas Liver Institute | San Antonio | Texas | 78215 | Recruiting |
| Endeavor Clinical Trials | San Antonio | Texas | 78240 | Recruiting |
| Stroobants Cardiovascular Center | Lynchburg | Virginia | 24501 | Recruiting |
| TPMG (Tidewater Physicians Multispecialty Group) Clinical Research | Newport News | Virginia | 23606 | Recruiting |
| Carilion Clinic | Roanoke | Virginia | 24014 | Recruiting |
| Eastside Research Associates | Redmond | Washington | 98052 | Recruiting |
| UW Medicine Diabetes Institute | Seattle | Washington | 98109 | Not yet recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 11 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07269210, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 21, 2026 · Synced Apr 23, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07269210 live on ClinicalTrials.gov.