A Study of IDE892 as Monotherapy and Combination in MTAP-deleted Advanced Solid Tumors
Public ClinicalTrials.gov record NCT07277413. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter Study Evaluating the Safety, Efficacy, and Pharmacokinetics of IDE892 as Monotherapy and Combination Therapy in Participants With MTAP-Deleted Advanced Solid Tumors
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a multicenter clinical study to evaluate the safety, efficacy, and Pharmacokinetics (PK) of IDE892 as monotherapy and in combination with other agents including IDE397 in participants with methylthioadenosine phosphorylase (MTAP)-deleted advanced solid tumors within indications of interest.
Study identification
- NCT ID
- NCT07277413
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 1
- Enrollment
- 260 participants
Conditions and interventions
Conditions
- NSCLC Adenocarcinoma
- Gastroesophageal Cancer (GC)
- Gastric Adenocarcinoma
- Adenocarcinoma of Esophagus
- Squamous Cell Car. - Esophagus
- Urothelial Carcinoma (UC)
- Bladder Cancer
- Mesothelioma
- Pleural Mesothelioma
- Peritoneal Mesothelioma
- Non-Small Cell Lung Cancer NSCLC
- Pancreatic Cancer
- Biliary Tract Carcinoma
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 3, 2026
- Primary completion
- Apr 29, 2028
- Completion
- Apr 29, 2028
- Last update posted
- Aug 4, 2026
2026 – 2028
United States locations
- U.S. sites
- 17
- U.S. states
- 12
- U.S. cities
- 16
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Providence Medical Foundation | Santa Rosa | California | 95403 | Recruiting |
| Johns Hopkins Sibley Memorial Hospital | Washington D.C. | District of Columbia | 20016 | Recruiting |
| BRCR Global-Coral Springs | Coral Springs | Florida | 33065 | Recruiting |
| Sarah Cannon Research Institute at Florida Cancer Specialists | Orlando | Florida | 32827 | Recruiting |
| Moffitt Cancer Center | Tampa | Florida | 33612 | Recruiting |
| Nebraska Cancer Specialists | Omaha | Nebraska | 68130 | Recruiting |
| START Astera, LLC | East Brunswick | New Jersey | 08816 | Recruiting |
| Columbia University Irving Medical Center | New York | New York | 10032 | Recruiting |
| Sidney Kimmel Comprehensive Cancer Center Thomas Jefferson University | Philadelphia | Pennsylvania | 19107 | Recruiting |
| Sarah Cannon Research Institute | Nashville | Tennessee | 37203 | Recruiting |
| START Dallas Fort Worth | Fort Worth | Texas | 76104 | Recruiting |
| MD Anderson | Houston | Texas | 77030 | Recruiting |
| NEXT Oncology Houston | Houston | Texas | 77054 | Recruiting |
| NEXT Oncology Dallas | Irving | Texas | 75039 | Recruiting |
| START Mountain Region, LLC | West Valley City | Utah | 84119 | Recruiting |
| NEXT Oncology Virginia | Fairfax | Virginia | 22031 | Recruiting |
| Swedish Cancer Institute | Seattle | Washington | 98104 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07277413, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 4, 2026 · Synced Sep 6, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07277413 live on ClinicalTrials.gov.