COMparison Between Anakinra and Tocilizumab in NORSE - "COMBAT-NORSE"
Public ClinicalTrials.gov record NCT07281027. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Comparing the Effects of Anakinra and Tocilizumab on Outcomes in Patients With New-Onset Refractory Status Epilepticus
Study identification
- NCT ID
- NCT07281027
- Recruitment status
- Not yet recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Yale University
- Other
- Enrollment
- 438 participants
Conditions and interventions
Conditions
Interventions
- Anakinra Drug
- Standard medical treatment Other
- Tocilizumab Drug
Drug · Other
Eligibility (public fields only)
- Age range
- 2 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 28, 2026
- Primary completion
- Mar 30, 2030
- Completion
- Sep 29, 2030
- Last update posted
- Dec 14, 2025
2026 – 2030
United States locations
- U.S. sites
- 25
- U.S. states
- 16
- U.S. cities
- 20
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Barrow Institute | Phoenix | Arizona | 85013 | — |
| Children's Hospital Colorado | Aurora | Colorado | 80045 | — |
| Yale New Haven Hospital | New Haven | Connecticut | 06520 | — |
| Children's National (DC) | Washington D.C. | District of Columbia | 20010 | — |
| University of Florida | Gainesville | Florida | 32611 | — |
| University of Chicago | Chicago | Illinois | 60637 | — |
| Northwestern University | Evanston | Illinois | 60208 | — |
| Mass General (MGH) | Boston | Massachusetts | 02114 | — |
| Beth Israel Deaconess | Boston | Massachusetts | 02215 | — |
| Boston Children's Hospital | Boston | Massachusetts | 02215 | — |
| Mayo Clinic | Rochester | Minnesota | 55905 | — |
| University of Nebraska | Lincoln | Nebraska | 68588 | — |
| New York University | New York | New York | 10012 | — |
| Columbia University | New York | New York | 10027 | — |
| Mount Sinai (NY) | New York | New York | 10029 | — |
| University of Cincinnati | Cincinnati | Ohio | 45221 | — |
| Cleveland Clinic | Cleveland | Ohio | 44195 | — |
| Oregon Health and Science University | Portland | Oregon | 97239 | — |
| Children's Hospital Philadelphia (CHOP) | Philadelphia | Pennsylvania | 19104 | — |
| University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| UT Southwestern Medical Center | Dallas | Texas | 75390 | — |
| Baylor/Texas Children's | Houston | Texas | 77030 | — |
| Seattle Children's Hospital | Seattle | Washington | 98105 | — |
| University of Wisconsin | Madison | Wisconsin | 53706 | — |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 8 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07281027, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 14, 2025 · Synced May 4, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07281027 live on ClinicalTrials.gov.