Hematopoietic Stem Cell Transplantation (HSCT) for Common Variable Immunodeficiency (CVID) and Other Autoimmune Manifestations of Primary Immune Regulatory Disorders (PIRD)
Public ClinicalTrials.gov record NCT07284641. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Study identification
- NCT ID
- NCT07284641
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Paul Szabolcs
- Other
- Enrollment
- 25 participants
Conditions and interventions
Conditions
- CD40 Deficiency
- CD40 Ligand Deficiency
- Chronic Granulomatous Disease
- Common Variable Immunodeficiency (CVID)
- DiGeorge Syndrome
- GATA2 Associated Immunodeficiency
- Hypomorphic RAG1 Deficiency
- Hypomorphic RAG2 Deficiency
- Immune Dysregulation
- Immune Dysregulation Polyendocrinopathy Enteropathy X-Linked Syndrome
- Mendelian Susceptibility to Mycobacterial Disease
- Omenn Syndrome
- Primary Immune Regulatory Disorder
- STAT 1 Gain of Function
- STAT 3 Gain of Function
Interventions
- Hematopoietic stem cell transplant (HSCT) Biological
Biological
Eligibility (public fields only)
- Age range
- 5 Years to 40 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 28, 2026
- Primary completion
- Jan 31, 2030
- Completion
- Jan 31, 2031
- Last update posted
- Feb 19, 2026
2026 – 2031
United States locations
- U.S. sites
- 1
- U.S. states
- 1
- U.S. cities
- 1
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| UPMC Children's Hospital of Pittsburgh | Pittsburgh | Pennsylvania | 15224 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07284641, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 19, 2026 · Synced May 6, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07284641 live on ClinicalTrials.gov.