A Study to Evaluate the Efficacy of Cemsidomide + Dexamethasone in Participants With Relapsed/Refractory Multiple Myeloma

ClinicalTrials.gov ID: NCT07284758

Public ClinicalTrials.gov record NCT07284758. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced Oct 6, 2026, 2:49 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2, Open-Label, Single-Arm, Multicenter Study to Evaluate the Efficacy of Cemsidomide + Dexamethasone in Subjects With Relapsed/Refractory Multiple Myeloma

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This is a Phase 2, open-label, single-arm, multicenter study to assess the antimyeloma activity and further characterize the safety, tolerability, PK, and PD of cemsidomide in combination with dexamethasone in participants with relapsed/refractory multiple myeloma (r/r MM).

Study identification

NCT ID: NCT07284758
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 2
Lead sponsor: C4 Therapeutics, Inc.; Industry
Enrollment: 100 participants

Conditions and interventions

Conditions

Interventions

Cemsidomide Drug
Dexamethasone Drug

Drug

Eligibility (public fields only)

Age range: 18 Years and older
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Feb 18, 2026 (Actual)
Primary completion: Mar 2030 (Estimated)
Completion: Mar 2030 (Estimated)
Last update posted: Aug 6, 2026

2026 – 2030

United States locations

U.S. sites: 20
U.S. states: 16
U.S. cities: 19

Facility	City	State	ZIP	Site status
Clearview Cancer Institute	Huntsville	Alabama	35805	Recruiting
Mayo Clinic - Arizona	Phoenix	Arizona	85054	Recruiting
HonorHealth	Scottsdale	Arizona	85258	Recruiting
Berenson Cancer Center	West Hollywood	California	90069	Recruiting
Mayo Clinic - Florida	Jacksonville	Florida	32224	Recruiting
Winship Cancer Institute, Emory University	Atlanta	Georgia	30322	Recruiting
Indiana University Health	Indianapolis	Indiana	46202	Recruiting
University of Iowa	Iowa City	Iowa	52242	Recruiting
Karmanos Cancer Institute	Detroit	Michigan	48201	Recruiting
START Midwest	Grand Rapids	Michigan	49546	Recruiting
Mayo Clinic - Minnesota	Rochester	Minnesota	55905	Recruiting
Washington University/Siteman Cancer Center	St Louis	Missouri	63108	Recruiting
University of Nebraska Medical Center	Omaha	Nebraska	68198	Recruiting
The Tisch Cancer Institute/Mount Sinai	New York	New York	10029	Recruiting
Memorial Sloan Kettering Cancer Center	New York	New York	10065	Recruiting
UNC Hospitals Adult Oncology Clinics	Chapel Hill	North Carolina	27514	Recruiting
Tennessee Oncology	Nashville	Tennessee	37203	Recruiting
START San Antonio	San Antonio	Texas	78229	Recruiting
University of Wisconsin - Carbone Cancer Center	Madison	Wisconsin	53792	Recruiting
MCW-Clinical Cancer Center at Froedtert Hospital Campus	Milwaukee	Wisconsin	53226	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT07284758, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Aug 6, 2026 · Synced Oct 6, 2026

Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT07284758 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →