ClinicalTrials.gov record
A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer
ClinicalTrials.gov ID: NCT07284849
Public ClinicalTrials.gov record NCT07284849. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-Blind, Phase 3 Study of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to evaluate the efficacy and safety of standard-of-care chemotherapy and bevacizumab with or without INCA33890 in the first-line treatment of metastatic microsatellite stable colorectal cancer.
Study identification
- NCT ID
- NCT07284849
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 700 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 4, 2026
- Primary completion
- Dec 28, 2028
- Completion
- Sep 27, 2029
- Last update posted
- Aug 5, 2026
2026 – 2029
United States locations
- U.S. sites
- 71
- U.S. states
- 29
- U.S. cities
- 63
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Mitchell Cancer Institute | Mobile | Alabama | 36604 | Not yet recruiting |
| The University of Arizona Cancer Center | Tucson | Arizona | 85719 | Not yet recruiting |
| Roche Tissue Diagnostics, Companion Diagnostics | Tucson | Arizona | 85755 | Recruiting |
| Memorial Care Orange Coast Medical Center | Fountain Valley | California | 92708 | Recruiting |
| Providence Medical Foundation | Fullerton | California | 92835 | Recruiting |
| Cancer & Blood Research Center | Los Alamitos | California | 90720 | Recruiting |
| University of California Los Angeles Health | Los Angeles | California | 90095 | Not yet recruiting |
| Sarah Cannon Research Institute Scri Oncology Partners | Aurora | Colorado | 80012 | Recruiting |
| Hartford Hospital | Hartford | Connecticut | 06102 | Not yet recruiting |
| George Washington University | Washington D.C. | District of Columbia | 20037 | Not yet recruiting |
| Florida Oncology & Hematology | Fort Myers | Florida | 33912 | Recruiting |
| University of Florida Health | Gainesville | Florida | 32610 | Not yet recruiting |
| Sylvester Comprehensive Cancer Center | Miami | Florida | 33136 | Recruiting |
| Advent Health | Orlando | Florida | 32804 | Not yet recruiting |
| Orlando Health Cancer Institute Downtown Orlando | Orlando | Florida | 32806 | Not yet recruiting |
| Ascension Sacred Heart Pensacola | Pensacola | Florida | 32504 | Recruiting |
| Tampa General Hospital-Cancer Institute | Tampa | Florida | 33606 | Not yet recruiting |
| Piedmont Cancer Institute | Locust Grove | Georgia | 30248 | Not yet recruiting |
| University of Hawaii Cancer Center | Honolulu | Hawaii | 96813-2402 | Not yet recruiting |
| St Lukes Mountain States Tumor Institute Msti Boise | Boise | Idaho | 83712 | Not yet recruiting |
| Sih Cancer Institute | Carterville | Illinois | 62918 | Recruiting |
| University of Illinois Cancer Center | Chicago | Illinois | 60612 | Not yet recruiting |
| Endeavor Health | Evanston | Illinois | 60201 | Not yet recruiting |
| Springfield Clinic | Springfield | Illinois | 62703 | Recruiting |
| Community Health Network, Inc. | Indianapolis | Indiana | 46250 | Recruiting |
| Hematology Oncology of Indiana | Indianapolis | Indiana | 46260 | Recruiting |
| University of Iowa Hospital and Clinics | Iowa City | Iowa | 52242 | Not yet recruiting |
| Saint Agnes Hospital | Baltimore | Maryland | 21229-5201 | Not yet recruiting |
| Cancer Center For Blood Disorders A Division of American Oncology Partners P.A | Bethesda | Maryland | 20817 | Recruiting |
| Sarah Cannon Research Institute Scri Oncology Partners | Brandywine | Maryland | 20613 | Recruiting |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | Not yet recruiting |
| Oncura Health | Boston | Massachusetts | 02115 | Not yet recruiting |
| St. Joseph Mercy Hospital | Ann Arbor | Michigan | 48106 | Recruiting |
| Henry Ford Hospital | Detroit | Michigan | 48202 | Not yet recruiting |
| Missouri Cancer Associates | Columbia | Missouri | 65201 | Recruiting |
| Saint Luke'S Hospital of Kansas City | Kansas City | Missouri | 64111 | Not yet recruiting |
| Midamerica Cancer Care | Kansas City | Missouri | 64121 | Recruiting |
| Oncology Hematology Associates | Springfield | Missouri | 65807 | Recruiting |
| Washington University School of Medicine | St Louis | Missouri | 63110 | Recruiting |
| Morristown Medical Center | Morristown | New Jersey | 07960 | Not yet recruiting |
| Presbyterian Rust Medical Center | Rio Rancho | New Mexico | 87124 | Recruiting |
| Icahn School of Medicine At Mount Sinai | New York | New York | 10019 | Not yet recruiting |
| Memorial Sloan Kettering Cancer Center | New York | New York | 10065 | Not yet recruiting |
| Ny Cancer and Blood Specialists | Shirley | New York | 11967 | Recruiting |
| Montefiore Einstein For Cancer Care | The Bronx | New York | 10461 | Not yet recruiting |
| Messino Cancer Center | Asheville | North Carolina | 28806 | Recruiting |
| The University of North Carolina At Chapel Hill | Chapel Hill | North Carolina | 27514 | Recruiting |
| Oncology Specialists of Charlotte | Charlotte | North Carolina | 28207 | Not yet recruiting |
| University of Cincinnati Cancer Institute | Cincinnati | Ohio | 45219 | Not yet recruiting |
| Case Comprehensive Cancer Center | Cleveland | Ohio | 44106 | Not yet recruiting |
| Ohio State University-Arthur G James Comprehensive Cancer Center | Columbus | Ohio | 43210 | Not yet recruiting |
| Ohio Health | Columbus | Ohio | 43214 | Not yet recruiting |
| Alliance Cancer Specialists | Doylestown | Pennsylvania | 18901 | Recruiting |
| Penn State Milton S. Hershey Medical Center | Hershey | Pennsylvania | 17033 | Not yet recruiting |
| Hillman Cancer Center | Monroeville | Pennsylvania | 15146 | Not yet recruiting |
| University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | Not yet recruiting |
| Allegheny General Hospital Cancer Institute | Pittsburgh | Pennsylvania | 15212 | Recruiting |
| Cancer Care Associates of York | York | Pennsylvania | 17403 | Recruiting |
| Avera Cancer Institute | Sioux Falls | South Dakota | 57105 | Recruiting |
| Provision Center For Biomedical Research | Knoxville | Tennessee | 37909 | Recruiting |
| Ascension Seton Spclty Care Ctr | Austin | Texas | 78712 | Not yet recruiting |
| Texas Oncology | Austin | Texas | 78745 | Recruiting |
| University of Texas Southwestern Medical Center | Dallas | Texas | 75235 | Not yet recruiting |
| Md Anderson Cancer Center | Houston | Texas | 77030 | Recruiting |
| Baylor Scott & White Health | Temple | Texas | 76508 | Not yet recruiting |
| University of Virginia Medical Center | Charlottesville | Virginia | 22908 | Not yet recruiting |
| Mary Washington Healthcare | Fredericksburg | Virginia | 22405 | Not yet recruiting |
| Shenandoah Oncology | Winchester | Virginia | 22601 | Recruiting |
| Vandalia Health Charleston Area Medical Center | Charleston | West Virginia | 25304 | Not yet recruiting |
| West Virginia University Cancer Institute | Morgantown | West Virginia | 26506 | Recruiting |
| Thedacare Medical Oncology | Appleton | Wisconsin | 54911 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 183 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07284849, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 5, 2026 · Synced Sep 1, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07284849 live on ClinicalTrials.gov.