ClinicalTrials.gov record
A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer
ClinicalTrials.gov ID: NCT07284849
Public ClinicalTrials.gov record NCT07284849. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
ClinicalTrials.gov public records Last synced May 9, 2026, 7:30 PM EDT
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-Blind, Phase 3 Study of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer
Study identification
- NCT ID
- NCT07284849
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Incyte Corporation
- Industry
- Enrollment
- 700 participants
Conditions and interventions
Conditions
Interventions
- Bevacizumab Drug
- FOLFOX Drug
- INCA33890 Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 4, 2026
- Primary completion
- Dec 28, 2028
- Completion
- Sep 27, 2029
- Last update posted
- May 7, 2026
2026 – 2029
United States locations
- U.S. sites
- 80
- U.S. states
- 29
- U.S. cities
- 68
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Ironwood Cancer & Research Centers | Chandler | Arizona | 85224-5665 | Withdrawn |
| The University of Arizona Cancer Center | Tucson | Arizona | 85719 | Not yet recruiting |
| Roche Tissue Diagnostics, Companion Diagnostics | Tucson | Arizona | 85755 | Recruiting |
| Los Angeles Cancer Network | Anaheim | California | 92801 | Not yet recruiting |
| Toi Clinical Research | Cerritos | California | 90703 | Not yet recruiting |
| Memorial Care Orange Coast Medical Center | Fountain Valley | California | 92708 | Recruiting |
| Providence Medical Foundation | Fullerton | California | 92835 | Not yet recruiting |
| University of California Los Angeles Health | Los Angeles | California | 90095 | Not yet recruiting |
| Sarah Cannon Research Institute Scri Oncology Partners | Aurora | Colorado | 80012 | Recruiting |
| Hartford Hospital | Hartford | Connecticut | 06102 | Not yet recruiting |
| George Washington University | Washington D.C. | District of Columbia | 20037 | Not yet recruiting |
| Florida Oncology & Hematology | Fort Myers | Florida | 33912 | Not yet recruiting |
| University of Florida Health | Gainesville | Florida | 32610 | Not yet recruiting |
| Sylvester Comprehensive Cancer Center | Miami | Florida | 33136 | Not yet recruiting |
| Advent Health | Orlando | Florida | 32804 | Not yet recruiting |
| Orlando Health Cancer Institute Downtown Orlando | Orlando | Florida | 32806 | Not yet recruiting |
| Ascension Sacred Heart Pensacola | Pensacola | Florida | 32504 | Not yet recruiting |
| Tampa General Hospital-Cancer Institute | Tampa | Florida | 33606 | Not yet recruiting |
| H. Lee Moffitt Cancer Center and Research Institute Hospital | Tampa | Florida | 33612-9497 | Withdrawn |
| Piedmont Cancer Institute | Locust Grove | Georgia | 30248 | Not yet recruiting |
| University of Hawaii Cancer Center | Honolulu | Hawaii | 96813-2402 | Not yet recruiting |
| St Lukes Mountain States Tumor Institute Msti Boise | Boise | Idaho | 83712 | Not yet recruiting |
| University of Illinois Cancer Center | Chicago | Illinois | 60612 | Not yet recruiting |
| Endeavor Health | Evanston | Illinois | 60201 | Not yet recruiting |
| Springfield Clinic | Springfield | Illinois | 62702 | Not yet recruiting |
| Iu Simon Cancer Center | Indianapolis | Indiana | 46202 | Withdrawn |
| Community Health Network, Inc. | Indianapolis | Indiana | 46250 | Not yet recruiting |
| Hematology Oncology of Indiana | Indianapolis | Indiana | 46260 | Not yet recruiting |
| University of Iowa Hospital and Clinics | Iowa City | Iowa | 52242 | Not yet recruiting |
| Ochsner Clinic Foundation Ocf Ochsner Cancer Institute Oci | New Orleans | Louisiana | 70121 | Withdrawn |
| Saint Agnes Hospital | Baltimore | Maryland | 21229-5201 | Not yet recruiting |
| Cancer Center For Blood Disorders A Division of American Oncology Partners P.A | Bethesda | Maryland | 20817 | Recruiting |
| Sarah Cannon Research Institute Scri Oncology Partners | Brandywine | Maryland | 20613 | Recruiting |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | Not yet recruiting |
| University of Michigan | Ann Arbor | Michigan | 48109 | Withdrawn |
| St. Joseph Mercy Hospital | Ann Arbor | Michigan | 48197 | Not yet recruiting |
| Henry Ford Hospital | Detroit | Michigan | 48202 | Not yet recruiting |
| Missouri Cancer Associates | Columbia | Missouri | 65201 | Recruiting |
| Saint Luke'S Hospital of Kansas City | Kansas City | Missouri | 64111 | Not yet recruiting |
| Midamerica Cancer Care | Kansas City | Missouri | 64121 | Recruiting |
| Oncology Hematology Associates | Springfield | Missouri | 65807 | Recruiting |
| Washington University School of Medicine | St Louis | Missouri | 63110 | Recruiting |
| Morristown Medical Center | Morristown | New Jersey | 07960 | Not yet recruiting |
| Presbyterian Rust Medical Center | Rio Rancho | New Mexico | 87124 | Not yet recruiting |
| Monter Cancer Center | New Hyde Park | New York | 11042 | Withdrawn |
| Icahn School of Medicine At Mount Sinai | New York | New York | 10019 | Not yet recruiting |
| Memorial Sloan Kettering Cancer Center | New York | New York | 10065 | Not yet recruiting |
| University of Rochester | Rochester | New York | 14623-2327 | Not yet recruiting |
| Ny Cancer and Blood Specialists | Shirley | New York | 11967 | Not yet recruiting |
| Montefiore Einstein For Cancer Care | The Bronx | New York | 10461 | Not yet recruiting |
| Messino Cancer Center | Asheville | North Carolina | 28806 | Not yet recruiting |
| The University of North Carolina At Chapel Hill | Chapel Hill | North Carolina | 27514 | Not yet recruiting |
| Oncology Specialists of Charlotte | Charlotte | North Carolina | 28207 | Not yet recruiting |
| University of Cincinnati Cancer Institute | Cincinnati | Ohio | 45219 | Not yet recruiting |
| Ohio State University-Arthur G James Comprehensive Cancer Center | Columbus | Ohio | 43210 | Not yet recruiting |
| Ohio Health | Columbus | Ohio | 43214 | Not yet recruiting |
| St. Luke'S Health Network | Bethlehem | Pennsylvania | 18015 | Not yet recruiting |
| Alliance Cancer Specialists | Doylestown | Pennsylvania | 18901 | Recruiting |
| Penn State Milton S. Hershey Medical Center | Hershey | Pennsylvania | 17933 | Not yet recruiting |
| Hillman Cancer Center | Monroeville | Pennsylvania | 15146 | Not yet recruiting |
| University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | Not yet recruiting |
| Sidney Kimmel Comprehensive Cancer Center | Philadelphia | Pennsylvania | 19107 | Withdrawn |
| Allegheny General Hospital Cancer Institute | Pittsburgh | Pennsylvania | 15212 | Not yet recruiting |
| Cancer Care Associates of York | York | Pennsylvania | 17403 | Recruiting |
| Avera Cancer Institute | Sioux Falls | South Dakota | 57105 | Not yet recruiting |
| Provision Center For Biomedical Research | Knoxville | Tennessee | 37909 | Recruiting |
| Sarah Cannon Research Institute Scri Oncology Partners | Nashville | Tennessee | 37203 | Withdrawn |
| Tennessee Oncology, Pllc | Nashville | Tennessee | 37203 | Withdrawn |
| Ascension Seton Spclty Care Ctr | Austin | Texas | 78712 | Not yet recruiting |
| Texas Oncology | Austin | Texas | 78745 | Recruiting |
| University of Texas Southwestern Medical Center | Dallas | Texas | 75235 | Not yet recruiting |
| Md Anderson Cancer Center | Houston | Texas | 77030 | Not yet recruiting |
| Baylor Scott & White Health | Temple | Texas | 76508 | Not yet recruiting |
| University of Virginia Medical Center | Charlottesville | Virginia | 22908 | Not yet recruiting |
| Inova Schar Cancer Institute | Fairfax | Virginia | 22031-4867 | Withdrawn |
| Shenandoah Oncology | Winchester | Virginia | 22601 | Recruiting |
| Fred Hutchinson Cancer Center | Seattle | Washington | 98109 | Withdrawn |
| Cancer Care Northwest | Spokane | Washington | 99202 | Withdrawn |
| Vandalia Health Charleston Area Medical Center | Charleston | West Virginia | 25304 | Not yet recruiting |
| West Virginia University Cancer Institute | Morgantown | West Virginia | 26506 | Not yet recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 193 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07284849, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 7, 2026 · Synced May 9, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07284849 live on ClinicalTrials.gov.