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Active, not recruiting Phase 3 Interventional

Efficacy and Safety of Ribupatide Administered Once Weekly Compared With Semaglutide and Placebo in Participants Living With Obesity Who Do Not Have Diabetes

ClinicalTrials.gov ID: NCT07284979

Public ClinicalTrials.gov record NCT07284979. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 19, 2026, 11:55 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 3, Randomized, Active- and Placebo-Controlled, Partially-Blinded Study to Compare the Efficacy and Safety of KAI-9531 Administered Once Weekly Versus Semaglutide and Placebo in Participants Living With Obesity Who Do Not Have Diabetes

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The primary objective of this study is to demonstrate that ribupatide (KAI-9531) subcutaneous (SC) injection once weekly is superior to semaglutide SC once weekly and to placebo SC once weekly on percent change in body weight.

Study identification

NCT ID
NCT07284979
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 3
Lead sponsor
Kailera
Industry
Enrollment
1,270 participants

Conditions and interventions

Conditions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Dec 30, 2025 (Actual)
Primary completion
Mar 2028 (Estimated)
Completion
Apr 2028 (Estimated)
Last update posted
Oct 6, 2026

2025 – 2028

United States locations

U.S. sites
28
U.S. states
19
U.S. cities
27
Facility City State ZIP Site status
Kailera Clinical Site Glendale Arizona 85308 —
Kailera Clinical Site Phoenix Arizona 85012 —
Kailera Clinical Site Little Rock Arkansas 72205 —
Kailera Clinical Site Northridge California 91325 —
Kailera Clinical Site Oceanside California 92058 —
Kailera Clinical Site Hamden Connecticut 06517 —
Kailera Clinical Site Stamford Connecticut 06905 —
Kailera Clinical Site Orange City Florida 32763 —
Kailera Clinical Site Albany Georgia 31707 —
Kailera Clinical Site Chicago Illinois 60640 —
Kailera Clinical Site Skokie Illinois 60077 —
Kailera Clinical Site Newton Kansas 67114 —
Kailera Clinical Site Shreveport Louisiana 71105 —
Kailera Clinical Site Farmington Hills Michigan 48334 —
Kailera Clinical Site Missoula Montana 59804 —
Kailera Clinical Site Las Vegas Nevada 89148 —
Kailera Clinical Site Albany New York 12203 —
Kailera Clinical Site Morehead City North Carolina 28557 —
Kailera Clinical Site Morrisville North Carolina 27560 —
Kailera Clinical Site Norman Oklahoma 73069 —
Kailera Clinical Site East Greenwich Rhode Island 02818 —
Kailera Clinical Site North Charleston South Carolina 29405 —
Kailera Clinical Site Spartanburg South Carolina 29303 —
Kailera Clinical Site Brownsville Texas 78526 —
Kailera Clinical Site #1 San Antonio Texas 78229 —
Kailera Clinical Site #2 San Antonio Texas 78229 —
Kailera Clinical Site Manassas Virginia 20110 —
Kailera Clinical Site Richmond Virginia 23236 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 32 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT07284979, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Oct 6, 2026 · Synced Oct 19, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT07284979 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →