Study is to Assess the Safety and Tolerability of VTx-002 in Participants With ALS
Public ClinicalTrials.gov record NCT07287397. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Phase 1/2 Investigation of Novel Experimental Regimen in Amyotrophic Lateral Sclerosis (Pioneer-ALS): An Open-Label, Uncontrolled, Multicenter Study to Assess the Safety and Tolerability of Two Doses of VTx-002
Study identification
- NCT ID
- NCT07287397
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Lead sponsor
- Vector Y Therapeutics
- Industry
- Enrollment
- 12 participants
Conditions and interventions
Conditions
Interventions
- Optional Rescue medication - Corticosteroids: Methylprednisolone Drug
- VTx-002 Genetic
Drug · Genetic
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 18, 2025
- Primary completion
- Oct 14, 2027
- Completion
- Oct 14, 2027
- Last update posted
- Apr 27, 2026
2025 – 2027
United States locations
- U.S. sites
- 7
- U.S. states
- 6
- U.S. cities
- 7
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| St Joseph's Hospital and medical Center - Barrow Neurological Institute | Phoenix | Arizona | 85013 | Not yet recruiting |
| University of California San Diego Medical Center | San Diego | California | 92121 | Recruiting |
| Mayo Clinic in Florida | Jacksonville | Florida | 32224 | Recruiting |
| University of Miami School of Science | Miami | Florida | 33136 | Not yet recruiting |
| Sean M. Healey & AMG Center for ALS at Massachusetts General Hospital | Boston | Massachusetts | 02114 | Recruiting |
| Herbert Irving Comprehensive Cancer Center | New York | New York | 10032 | Not yet recruiting |
| University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | Not yet recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 4 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07287397, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 27, 2026 · Synced May 8, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07287397 live on ClinicalTrials.gov.