EncompaSSc: Evaluation of MTX-474 in Participants With Diffuse Cutaneous Systemic Sclerosis (dcSSc)
Public ClinicalTrials.gov record NCT07287670. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2 Randomized, Double-blind, Placebo-Controlled Study to Assess the Safety and Efficacy of MTX-474 in the Treatment of Participants With Diffuse Cutaneous Systemic Sclerosis (dcSSc)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
A Phase 2 Randomized, Double-blind, Placebo-Controlled Study of the Safety and Efficacy of MTX-474 in Participants with Diffuse Cutaneous Systemic Sclerosis (dcSSc)
Study identification
- NCT ID
- NCT07287670
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 85 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 15, 2026
- Primary completion
- Nov 30, 2028
- Completion
- Nov 30, 2028
- Last update posted
- Aug 4, 2026
2026 – 2028
United States locations
- U.S. sites
- 23
- U.S. states
- 13
- U.S. cities
- 22
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| EncompaSSc site in Phoenix, AZ | Phoenix | Arizona | 85054 | Not yet recruiting |
| EncompaSSc site in La Jolla, CA | La Jolla | California | 92037 | Not yet recruiting |
| EncompaSSc site in Loma Linda, CA | Loma Linda | California | 92350 | Not yet recruiting |
| University of California Los Angeles Scleroderma Center | Los Angeles | California | 90095 | Recruiting |
| NewportNativeMD, Inc. | Newport Beach | California | 92663 | Recruiting |
| EncompaSSc site in Palo Alto, CA | Palo Alto | California | 94304 | Not yet recruiting |
| University of Colorado Center for Lungs/Breathing/Scleroderma Clinic | Aurora | Colorado | 80045 | Recruiting |
| Clinical Research of West Florida | Clearwater | Florida | 33765 | Recruiting |
| EncompaSSc site in Sarasota, FL | Sarasota | Florida | 34239 | Not yet recruiting |
| Clinical Research of West Florida | Tampa | Florida | 33606 | Recruiting |
| EncompaSSc site in Kansas City, KS | Kansas City | Kansas | 66103 | Not yet recruiting |
| Johns Hopkins University | Baltimore | Maryland | 21205 | Recruiting |
| Brigham and Women's Hospital | Boston | Massachusetts | 02115 | Recruiting |
| Boston Medical Center | Boston | Massachusetts | 02118 | Recruiting |
| EncompaSSc site in Minneapolis, MN | Minneapolis | Minnesota | 55455 | Not yet recruiting |
| EncompaSSc site in Brooklyn, NY | Brooklyn | New York | 11201 | Not yet recruiting |
| EncompaSSc site in Cleveland, OH | Cleveland | Ohio | 44195 | Not yet recruiting |
| EncompaSSc site in Oklahoma City, OK | Oklahoma City | Oklahoma | 73104 | Not yet recruiting |
| EncompaSSc site in Philadelphia, PA | Philadelphia | Pennsylvania | 19107 | Not yet recruiting |
| EncompaSSc site in Pittsburgh, PA | Pittsburgh | Pennsylvania | 15219 | Not yet recruiting |
| Stryde Research - DFW | Allen | Texas | 75013 | Recruiting |
| Baylor Scott & White Research Institute | Dallas | Texas | 75246 | Recruiting |
| EncompaSSc site in Houston, TX | Houston | Texas | 77030 | Not yet recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 35 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07287670, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 4, 2026 · Synced Sep 5, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07287670 live on ClinicalTrials.gov.