Immunotherapy Biomarkers to Predict First-line PD(L)1-based Immunotherapy Response and Selection of Second-line Treatment in Stage IIIB-IV Non-small Cell Lung Cancer, IMMUNO-BIOMAP Trial

ClinicalTrials.gov ID: NCT07288034

Public ClinicalTrials.gov record NCT07288034. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced May 7, 2026, 12:12 PM EDT

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Official title

Immunotherapy Biomarker Collection for Metastatic NSCLC to Inform Adaptive Personalized Models Targeting Resistance (IMMUNO-BIOMAP)

Study identification

NCT ID: NCT07288034
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 2
Lead sponsor: City of Hope Medical Center; Other
Enrollment: 535 participants

Conditions and interventions

Conditions

Interventions

Adagrasib Drug
Anti-PD-L1 Monoclonal Antibody Biological
Anti-PD1 Monoclonal Antibody Biological
Bevacizumab Biological
Biopsy Procedure Procedure
Biospecimen Collection Procedure
Chemotherapy Drug
Computed Tomography Procedure
Durvalumab Biological
Magnetic Resonance Imaging Procedure
Monitoring Other
Positron Emission Tomography Procedure
Surveillance Behavioral
Tremelimumab Biological

Drug · Biological · Procedure + 2 more

Eligibility (public fields only)

Age range: 18 Years and older
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Apr 7, 2026
Primary completion: Oct 7, 2028
Completion: Oct 7, 2028
Last update posted: Apr 14, 2026

2026 – 2028

United States locations

U.S. sites: 13
U.S. states: 4
U.S. cities: 13

Facility	City	State	ZIP	Site status
CTCA at Western Regional Medical Center	Goodyear	Arizona	85338	Recruiting
City of Hope Corona	Corona	California	92882	Recruiting
City of Hope Medical Center	Duarte	California	91010	Recruiting
City of Hope Seacliff	Huntington Beach	California	92648	Recruiting
City of Hope at Irvine Lennar	Irvine	California	92618	Recruiting
City of Hope Antelope Valley	Lancaster	California	93534	Recruiting
City of Hope at Long Beach Elm	Long Beach	California	90813	Recruiting
City of Hope at Newport Beach Fashion Island	Newport Beach	California	92660	Recruiting
City of Hope South Pasadena	South Pasadena	California	91030	Recruiting
City of Hope South Bay	Torrance	California	90503	Recruiting
City of Hope Upland	Upland	California	91786	Recruiting
City of Hope Atlanta Cancer Center	Newnan	Georgia	30265	Recruiting
City of Hope at Chicago	Zion	Illinois	60099	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT07288034, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Apr 14, 2026 · Synced May 7, 2026

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The complete protocol, eligibility criteria, and contact information for NCT07288034 live on ClinicalTrials.gov.

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