ClinicalTrials.gov record
A Study of a Thyroid Hormone Receptor Beta Isoform (THRβ) Agonist and an Semicarbazide Sensitive Amine Oxidase (SSAO) Inhibitor, Alone and in Combination, in Adults With Presumed Metabolic Dysfunction-associated Steatohepatitis (MASH)
ClinicalTrials.gov ID: NCT07288138
Public ClinicalTrials.gov record NCT07288138. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
ClinicalTrials.gov public records Last synced Apr 23, 2026, 7:08 AM EDT
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2a, Randomized, Double-blind, Placebo-controlled, Multicenter Study to Assess the Efficacy and Safety of a THRβ Agonist (ECC4703), an SSAO Inhibitor (ECC0509), and Their Combination in Adults With Presumed MASH
Study identification
- NCT ID
- NCT07288138
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Eccogene
- Industry
- Enrollment
- 160 participants
Conditions and interventions
Interventions
- ECC0509 Drug
- ECC4703 Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 14, 2025
- Primary completion
- Sep 14, 2027
- Completion
- Sep 28, 2027
- Last update posted
- Apr 21, 2026
2025 – 2027
United States locations
- U.S. sites
- 53
- U.S. states
- 14
- U.S. cities
- 47
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Arizona Liver Health | Chandler | Arizona | 85224 | Recruiting |
| Arizona Liver Health - Peoria | Peoria | Arizona | 85381 | Recruiting |
| Adobe Clinical Research, LLC | Tucson | Arizona | 85712 | Recruiting |
| Arizona Liver Health - Tucson | Tucson | Arizona | 85712 | Recruiting |
| Arkansas Gastroenterology, P.A | Little Rock | Arkansas | 71913 | Recruiting |
| ARcare Center for Clinical Research | Little Rock | Arkansas | 77205 | Recruiting |
| ARK Clinical Research - Fountain Valley | Fountain Valley | California | 92708 | Recruiting |
| Ark Clinical Research | Long Beach | California | 90815 | Recruiting |
| Knowledge Research Center | Orange | California | 92868 | Recruiting |
| Synergy Healthcare | Bradenton | Florida | 33511 | Recruiting |
| Synergy Healthcare | Bradenton | Florida | 34209 | Recruiting |
| Health Awareness, Inc. | Jupiter | Florida | 33458 | Recruiting |
| Evolution Clinical Trials | Miami | Florida | 33122 | Recruiting |
| Floridian Clinical Research, LLC | Miami Lakes | Florida | 33016 | Recruiting |
| Ocala GI Research | Ocala | Florida | 34471 | Recruiting |
| Progressive Medical Research | Port Orange | Florida | 32127 | Recruiting |
| ClinCloud, LLC | Viera | Florida | 32940 | Recruiting |
| CenExel - iResearch | Decatur | Georgia | 30030 | Recruiting |
| Gastrointestinal Specialists of Georgia, PC | Marietta | Georgia | 30060 | Recruiting |
| Digestive Research Alliance of Michiana | South Bend | Indiana | 46635 | Recruiting |
| Tandem Clinical Research | Covington | Louisiana | 70433 | Recruiting |
| Tandem Clinical Research | Houma | Louisiana | 70360 | Recruiting |
| Tandem Clinical Research GI, LLC | Marrero | Louisiana | 70072 | Recruiting |
| Tandem Clinical Research | Metairie | Louisiana | 70006 | Recruiting |
| Delta Research Partners | Monroe | Louisiana | 71201 | Recruiting |
| Louisiana Research Center, LLC | Shreveport | Louisiana | 71105 | Recruiting |
| Delta Research Partners, LLC | West Monroe | Louisiana | 71291 | Recruiting |
| Mid-Atlantic GI Research | Greenbelt | Maryland | 20770 | Recruiting |
| Gastrointestinal Associates | Columbia | Missouri | 65201 | Recruiting |
| Gateway GI Research, LLC | St Louis | Missouri | 63141 | Recruiting |
| Premier Health Research | Sparta | New Jersey | 07871 | Recruiting |
| Akron Gastro Research | Akron | Ohio | 44333 | Recruiting |
| Digestive Specialists | Dayton | Ohio | 45414 | Recruiting |
| DSI Research | Springboro | Ohio | 45066 | Recruiting |
| Columbia Gastroenterology Associates, Llc | Columbia | South Carolina | 29204 | Recruiting |
| Pinnacle Clinical Research | Austin | Texas | 78757 | Recruiting |
| Bellaire Clinical Research | Bellaire | Texas | 77401 | Recruiting |
| South Texas Research Institute (STRI) - Brownsville | Brownsville | Texas | 78520 | Recruiting |
| Pinnacle Clinical Research | Corpus Christi | Texas | 78404 | Recruiting |
| South Texas Research Institute (STRI) | Edinburg | Texas | 78539 | Recruiting |
| Dallas Research Institute, LLC | Farmers Branch | Texas | 75234 | Recruiting |
| Care United Research | Forney | Texas | 75126 | Recruiting |
| Pinnacle Clinical Research - Georgetown | Georgetown | Texas | 78626 | Recruiting |
| Houston Research Institute - Medical Center | Houston | Texas | 770004 | Recruiting |
| Houston Research Institute | Houston | Texas | 77079 | Recruiting |
| Houston Research Institute - Pasadena | Pasadena | Texas | 77505 | Recruiting |
| Quality Research, Inc. | San Antonio | Texas | 78209 | Recruiting |
| Pinnacle Clinical Research - South San Antonio | San Antonio | Texas | 78222 | Recruiting |
| Pinnacle Clinical Research | San Antonio | Texas | 78229 | Recruiting |
| Sugarland Medical Associates (Sma) | Sugar Land | Texas | 77478 | Recruiting |
| Digestive Research of Central Texas | Waco | Texas | 76712 | Recruiting |
| Digestive Health Research of North Texas, LLC | Wichita Falls | Texas | 76301 | Recruiting |
| GI Select Health Research | Richmond | Virginia | 23236 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07288138, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 21, 2026 · Synced Apr 23, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07288138 live on ClinicalTrials.gov.