LEVEL-2: LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF-2
Public ClinicalTrials.gov record NCT07288398. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Double-Blind, Randomized, Placebo-Controlled Study of Levosimendan in Pulmonary Hypertension Patients With Heart Failure With Preserved Left Ventricular Ejection Fraction
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to assess the efficacy and safety of the study drug, levosimendan (given orally), compared to placebo in participants with pulmonary hypertension with heart failure with preserved left ventricular ejection fraction (PH-HFpEF) as measured by the change in 6-Minute Walk Distance.
Study identification
- NCT ID
- NCT07288398
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 540 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 85 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 3, 2026 (Actual)
- Primary completion
- Jun 30, 2028 (Estimated)
- Completion
- Jun 30, 2029 (Estimated)
- Last update posted
- Oct 15, 2026
2026 – 2029
United States locations
- U.S. sites
- 45
- U.S. states
- 23
- U.S. cities
- 43
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Tenax Investigational Site | Alexander City | Alabama | 35010 | — |
| Tenax Investigational Site | Tucson | Arizona | 85724 | — |
| Tenax Investigational Site | Sacramento | California | 95816 | — |
| Tenax Investigational Site | San Francisco | California | 94143 | — |
| Tenax Investigational Site | Stanford | California | 94305-5208 | — |
| Tenax Investigational Site | Torrance | California | 90502 | — |
| Tenax Investigational Site | Athens | Georgia | 30606 | — |
| Tenax Investigational Site | Atlanta | Georgia | 30322 | — |
| Tenax Investigational Site | Chicago | Illinois | 60611-4494 | — |
| Tenax Investigational Site | Chicago | Illinois | 60637 | — |
| Tenax Investigational Site | Mount Prospect | Illinois | 60056 | — |
| Tenax Investigational Site | Peoria | Illinois | 61636 | — |
| Tenax Investigational Site | Indianapolis | Indiana | 46260 | — |
| Tenax Investigational Site | New Orleans | Louisiana | 70115-6969 | — |
| Tenax Investigational Site | West Monroe | Louisiana | 71291 | — |
| Tenax Investigational Site | Boston | Massachusetts | 02114-2621 | — |
| Tenax Investigational Site | Ann Arbor | Michigan | 48109 | — |
| Tenax Investigational Site | Ypsilanti | Michigan | 48197 | — |
| Tenax Investigational Site | Minneapolis | Minnesota | 55455 | — |
| Tenax Investigational Site | Rochester | Minnesota | 55905 | — |
| Tenax Investigational Site | Kansas City | Missouri | 64111 | — |
| Tenax Investigational Site | St Louis | Missouri | 63136 | — |
| Tenax Investigational Site | Omaha | Nebraska | 68198 | — |
| Tenax Investigational Site | Reno | Nevada | 89502 | — |
| Tenax Investigational Site | New York | New York | 10021 | — |
| Tenax Investigational Site | New York | New York | 10032 | — |
| Tenax Investigational Site | Rochester | New York | 14617 | — |
| Tenax Investigational Site | Durham | North Carolina | 27710 | — |
| Tenax Investigational Site | Winston-Salem | North Carolina | 27101 | — |
| Tenax Investigational Site | Cleveland | Ohio | 44195-0001 | — |
| Tenax Investigational Site | Columbus | Ohio | 43210 | — |
| Tenax Investigational Site | Allentown | Pennsylvania | 18105 | — |
| Tenax Investigational Site | Pittsburgh | Pennsylvania | 15212 | — |
| Tenax Investigational Site | Wynnewood | Pennsylvania | 19096-3450 | — |
| Tenax Investigational Site | Charleston | South Carolina | 29425 | — |
| Tenax Investigational Site | Nashville | Tennessee | 37205 | — |
| Tenax Investigational Site | Austin | Texas | 78705 | — |
| Tenax Investigational Site | Dallas | Texas | 75390 | — |
| Tenax Investigational Site | El Paso | Texas | 79905-2707 | — |
| Tenax Investigational Site | Houston | Texas | 77030-2342 | — |
| Tenax Investigational Site | Charlottesville | Virginia | 22908 | — |
| Tenax Investigational Site | Norfolk | Virginia | 23507-1904 | — |
| Tenax Investigational Site | Seattle | Washington | 98122 | — |
| Tenax Investigational Site | Madison | Wisconsin | 53706 | — |
| Tenax Investigational Site | Marshfield | Wisconsin | 54449 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 95 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07288398, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 15, 2026 · Synced Oct 20, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT07288398 live on ClinicalTrials.gov.