Study of ENV-294 in Adults With Moderate-to-Severe Atopic Dermatitis
Public ClinicalTrials.gov record NCT07298395. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, 12-Week Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of ENV-294 in Adult Participants With Moderate-to-Severe Atopic Dermatitis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The goal of this clinical trial is to learn about the safety and effectiveness of ENV-294 in adults with moderate to severe atopic dermatitis. The main questions it will answer are: * Is there an impact on the severity and area of atopic dermatitis when participants take ENV-294 * What medical problems do participants have when taking ENV-294 Participants will: * Take drug ENV-294 or a placebo once every day for 12 weeks * Visit the clinic every 2 to 4 weeks for checkups and tests * Keep a diary of their symptoms and when they took their study drug * Return to the clinic for the final study visit at approximately week 16
Study identification
- NCT ID
- NCT07298395
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 60 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 21, 2025
- Primary completion
- Nov 30, 2026
- Completion
- Nov 30, 2026
- Last update posted
- Jul 28, 2026
2025 – 2026
United States locations
- U.S. sites
- 32
- U.S. states
- 16
- U.S. cities
- 30
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Enveda Investigative Site | Birmingham | Alabama | 35244 | Recruiting |
| Enveda Investigative Site | Hot Springs | Arkansas | 71913 | Recruiting |
| Enveda Investigative Site | Beverly Hills | California | 90212 | Recruiting |
| Enveda Investigative Site | Fremont | California | 94538 | Recruiting |
| Enveda Investigative Site | San Diego | California | 92121 | Recruiting |
| Enveda Investigative Site | San Diego | California | 92123 | Recruiting |
| Enveda Investigative Site | Santa Monica | California | 90403 | Recruiting |
| Enveda Investigative Site | West Hills | California | 91307 | Recruiting |
| Enveda Investigative Site | Fort Lauderdale | Florida | 33308 | Recruiting |
| Enveda Investigative Site | Miami | Florida | 33175 | Recruiting |
| Enveda Investigative Site | Miramar | Florida | 33027 | Recruiting |
| Enveda Investigative Site | Atlanta | Georgia | 30327 | Recruiting |
| Enveda Investigative Site | Chicago | Illinois | 60657 | Recruiting |
| Enveda Investigative Site | Clarksville | Indiana | 47129 | Recruiting |
| Enveda Investigative Site | New Albany | Indiana | 47150 | Recruiting |
| Enveda Investigative Site | West Lafayette | Indiana | 47906 | Recruiting |
| Enveda Investigative Site | Louisville | Kentucky | 40217 | Recruiting |
| Enveda Investigative Site | Louisville | Kentucky | 40241 | Recruiting |
| Enveda Investigative Site | Auburn Hills | Michigan | 48326 | Recruiting |
| Enveda Investigative Site | Bay City | Michigan | 48706 | Recruiting |
| Enveda Investigative Site | Clinton Township | Michigan | 48038 | Recruiting |
| Enveda Investigative Site | Warren | Michigan | 48088 | Recruiting |
| Enveda Investigative Site | Las Vegas | Nevada | 89145 | Recruiting |
| Enveda Investigative Site | New York | New York | 10029 | Recruiting |
| Enveda Investigative Site | Wilmington | North Carolina | 28405 | Recruiting |
| Enveda Investigative Site | Canton | Ohio | 44718 | Recruiting |
| Enveda Investigative Site | Mayfield Heights | Ohio | 44124 | Recruiting |
| Enveda Investigative Site | Camp Hill | Pennsylvania | 17011 | Recruiting |
| Enveda Investigative Site | Arlington | Texas | 76011 | Recruiting |
| Enveda Investigative Site | Houston | Texas | 77004 | Recruiting |
| Enveda Investigative Site | San Antonio | Texas | 78218 | Recruiting |
| Enveda Investigative Site | Norfolk | Virginia | 23502 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07298395, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 28, 2026 · Synced Sep 8, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07298395 live on ClinicalTrials.gov.