Pridopidine Phase 3 Study to Evaluate Efficacy and Safety in ALS
Public ClinicalTrials.gov record NCT07322003. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Pridopidine in Participants With Amyotrophic Lateral Sclerosis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The goal of this clinical trial is to learn if the drug pridopidine works to treat amyotrophic lateral sclerosis in adults. It will also help to learn about the safety of pridopidine. The main question it aims to answer is: Does pridopidine slow disease progression of ALS? Researchers will compare pridopidine to a placebo (a look-alike substance that contains no drug) to see if pridopidine works to treat ALS. Participants will: Take pridopidine or a placebo by mouth every day for 48 weeks. Afterwards, all participants will take pridopidine for another 48 weeks. Visit the clinic once every 1-3 months for checkups and tests
Study identification
- NCT ID
- NCT07322003
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 500 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 31, 2026
- Primary completion
- Feb 29, 2028
- Completion
- Feb 28, 2029
- Last update posted
- Sep 14, 2026
2026 – 2029
United States locations
- U.S. sites
- 18
- U.S. states
- 15
- U.S. cities
- 17
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Barrow Neurological Institute | Phoenix | Arizona | 85013 | Recruiting |
| California Pacific Medical Center | San Francisco | California | 94109 | Recruiting |
| University of Colorado CU Anschutz Neurology | Aurora | Colorado | 80045 | Recruiting |
| Mayo Clinic | Jacksonville | Florida | 32224 | Recruiting |
| University of South Florida | Tampa | Florida | 33612 | Recruiting |
| Emory University | Atlanta | Georgia | 30322 | Recruiting |
| Northwestern University | Chicago | Illinois | 60611 | Recruiting |
| University of Kansas | Fairway | Kansas | 66205 | Recruiting |
| Johns Hopkins University | Baltimore | Maryland | 21205 | Recruiting |
| Sean M. Healey & AMG Center for ALS | Boston | Massachusetts | 02114 | Recruiting |
| Washington University | St Louis | Missouri | 63110 | Recruiting |
| Somnos Clinical Research | Lincoln | Nebraska | 68506 | Recruiting |
| Eleanor and Lou Gehrig ALS Center at Columbia University | New York | New York | 10032 | Recruiting |
| Neuroscience Department at LKSM at Temple University | Philadelphia | Pennsylvania | 19140 | Recruiting |
| Texas Neurology | Dallas | Texas | 75206 | Recruiting |
| Baylor College of Medicine; McNair Medical Campus | Houston | Texas | 77030 | Recruiting |
| Swedish Medical Center | Seattle | Washington | 98122 | Recruiting |
| University of Washington | Seattle | Washington | 98195 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 37 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07322003, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 14, 2026 · Synced Sep 17, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07322003 live on ClinicalTrials.gov.