Efficacy and Safety of Vamifeport in Adult Participants With Homeostatic Iron Regulator Gene (HFE)-Related Hereditary Hemochromatosis
Public ClinicalTrials.gov record NCT07332091. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Multicenter, Randomized, Placebo-controlled, Double-blind Study of the Efficacy and Safety of Vamifeport in Adult Subjects With HFE-related Hereditary Hemochromatosis (FERROCLEAR Study)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a phase 2, multicenter, randomized, placebo-controlled, double-blind, parallel-group, proof-of-concept study to assess vamifeport in adult participants with homeostatic iron regulator gene-related hereditary hemochromatosis (HFE-HH). The primary objective of the study is to assess the effect of vamifeport treatment on magnetic resonance imaging (MRI)-based liver iron concentration (LIC) in adult participants with HFE-HH.
Study identification
- NCT ID
- NCT07332091
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 84 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 21, 2026
- Primary completion
- Mar 5, 2028
- Completion
- Apr 5, 2028
- Last update posted
- Aug 19, 2026
2026 – 2028
United States locations
- U.S. sites
- 19
- U.S. states
- 14
- U.S. cities
- 18
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Banner MD Anderson | Gilbert | Arizona | 85234-2165 | Not yet recruiting |
| Infinity Clinical Trials | San Diego | California | 92108 | Not yet recruiting |
| Medical Oncology Associates of San Diego | San Diego | California | 92123 | Not yet recruiting |
| Green Leaf Clinical Trials | Jacksonville | Florida | 32258 | Recruiting |
| Indiana University Health University Hospital | Indianapolis | Indiana | 46202-5149 | Recruiting |
| Ochsner Medical Complex - High Grove | Baton Rouge | Louisiana | 70836 | Recruiting |
| Johns Hopkins University School of Medicine | Baltimore | Maryland | 21205 | Not yet recruiting |
| American Oncology Partners, PA dba The Center for Cancer and Blood Disorders | Bethesda | Maryland | 20817 | Recruiting |
| James M. Stockman Cancer Institute | Frederick | Maryland | 21702-4337 | Recruiting |
| University of Michigan Health System (UMHS) | Ann Arbor | Michigan | 48109 | Not yet recruiting |
| Aspirus St. Luke's Clinic - Duluth - Oncology & Hematology | Duluth | Minnesota | 55805 | Recruiting |
| Hunterdon Hematology Oncology, LLC | Flemington | New Jersey | 08822 | Not yet recruiting |
| University of North Carolina at Chapel Hill | Chapel Hill | North Carolina | 27517-7518 | Recruiting |
| Duke University Medical Center (Duke South Clinics) -40 Duke Medicine Cir | Durham | North Carolina | 27710-4000 | Recruiting |
| Hightower Clinical - Oklahoma Cancer Center | Oklahoma City | Oklahoma | 73174 | Recruiting |
| Cancer Care Associates of York | York | Pennsylvania | 17403-5060 | Not yet recruiting |
| Intermountain Medical Center | Murray | Utah | 84107 | Not yet recruiting |
| Velocity Clinical Research - Seattle | Seattle | Washington | 98105 | Recruiting |
| Washington State Univ Elson S. Floyd College of Medicine | Spokane | Washington | 99202-2131 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 80 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07332091, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 19, 2026 · Synced Sep 7, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07332091 live on ClinicalTrials.gov.