AMAZE 1: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight Lose Weight
Public ClinicalTrials.gov record NCT07339423. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Efficacy and Safety of NNC0487-0111 s.c. Once-weekly in Participants With Obesity (AMAZE 1)
Study identification
- NCT ID
- NCT07339423
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Novo Nordisk A/S
- Industry
- Enrollment
- 1,150 participants
Conditions and interventions
Conditions
Interventions
- NNC0487-0111 Drug
- Placebo (matched to NNC0487-0111) Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 23, 2026
- Primary completion
- Jun 25, 2029
- Completion
- Aug 20, 2029
- Last update posted
- Apr 6, 2026
2026 – 2029
United States locations
- U.S. sites
- 22
- U.S. states
- 13
- U.S. cities
- 22
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| South Broward Research LLC | Miramar | Florida | 33027 | Recruiting |
| Clinical Neuroscience Solution | Orlando | Florida | 32801 | Recruiting |
| Hope Clin Res & Wellness | Conyers | Georgia | 30094 | Recruiting |
| Endeavor Health | Skokie | Illinois | 60077 | Recruiting |
| Midwest Inst For Clin Res | Indianapolis | Indiana | 46260 | Recruiting |
| StudyMetrix Research LLC | City of Saint Peters | Missouri | 63303 | Recruiting |
| New York Gastroenterology Associates | New York | New York | 10075 | Recruiting |
| UNC Eastowne Medical Office | Chapel Hill | North Carolina | 27514 | Recruiting |
| PharmQuest Life Sciences LLC | Greensboro | North Carolina | 27408 | Recruiting |
| Accellacare and KDCILM, LLC | Wilmington | North Carolina | 28401 | Not yet recruiting |
| UPA Ctr Weight and Eating Dis | Philadelphia | Pennsylvania | 19104 | Recruiting |
| Clinical Res Collaborative | Cumberland | Rhode Island | 02864 | Recruiting |
| Medical Uni of SC Charleston | Charleston | South Carolina | 29425 | Recruiting |
| Coastal Carolina Research Ctr | North Charleston | South Carolina | 29405 | Recruiting |
| Hillcrest Clinical Research | Simpsonville | South Carolina | 29681-1538 | Recruiting |
| Amarillo Medical Specialists | Amarillo | Texas | 79124 | Recruiting |
| Velocity Clinical Res-Dallas | Dallas | Texas | 75230-6855 | Recruiting |
| Care United Research, LLC | Forney | Texas | 75126 | Recruiting |
| Washington Cntr Weight Mgmt | Arlington | Virginia | 22206 | Recruiting |
| Health Res of Hampton Roads | Newport News | Virginia | 23606 | Recruiting |
| Selma Medical Associates | Winchester | Virginia | 22601-3834 | Recruiting |
| Rainier Clin Res Ctr Inc | Renton | Washington | 98057 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 50 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07339423, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 6, 2026 · Synced May 7, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07339423 live on ClinicalTrials.gov.