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Recruiting Phase 3 Interventional

A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight and Type 2 Diabetes

ClinicalTrials.gov ID: NCT07351058

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This page only displays public information reproduced from the official ClinicalTrials.gov record NCT07351058. It adds no medical advice, opinions, or eligibility judgments. The official record remains the source of truth for eligibility criteria, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced Nov 13, 2026, 7:29 AM EST

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Official title

A Phase III, Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study to Evaluate the Efficacy and Safety of Once-Weekly RO7795068 Administered to Participants With Obesity or Overweight and Type 2 Diabetes

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to assess the efficacy and safety of enicepatide, a dual glucagon-like peptide-1 (GLP-1)/glucose-dependent insulinotropic polypeptide (GIP) receptor agonist (RA), at multiple doses compared with placebo for weight management in participants with obesity or overweight and Type 2 diabetes mellitus (T2DM).

Study identification

NCT ID
NCT07351058
Recruitment status
Recruiting
Study type
Interventional
Phase
Phase 3
Lead sponsor
Hoffmann-La Roche
Industry
Enrollment
1,600 participants

Conditions and interventions

Interventions

Combination Product

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 23, 2026 (Actual)
Primary completion
Aug 7, 2028 (Estimated)
Completion
Aug 7, 2028 (Estimated)
Last update posted
Nov 9, 2026

2026 – 2028

United States locations

U.S. sites
45
U.S. states
21
U.S. cities
44
Facility City State ZIP Site status
Lakeview Clinical Research Guntersville Alabama 35976 Recruiting
Arizona Clinical Trials Tucson Arizona 85711 Recruiting
University of California Irvine Irvine California 92612 Recruiting
Orange County Research Center Lake Forest California 92630 Recruiting
Ark Clinical Research Long Beach California 90815 Recruiting
Catalina Research Institute, LLC Montclair California 91763 Recruiting
Infinity Clinical Research Norco California 92860 Recruiting
Prospective Research Innovations Inc. Rancho Cucamonga California 91730 Recruiting
Encompass Clinical Research Spring Valley California 91978 Recruiting
Emerson Clinical Research Institute Washington D.C. District of Columbia 20009 Recruiting
Tampa Bay Medical Research, Inc. Clearwater Florida 33761 Recruiting
Center for Diabetes, Obesity and Metabolism Inc Pembroke Pines Florida 33024 Recruiting
Progressive Medical Research Port Orange Florida 32127 Recruiting
Eirvera, LLC St. Petersburg Florida 33711 Recruiting
Centricity Research Columbus Georgia Multispecialty Columbus Georgia 31904 Recruiting
Atlanta Veterans Affairs Medical Center Decatur Georgia 30033 Recruiting
Rophe Adult and Pediatric Medicine/SKYCRNG Union City Georgia 30291 Recruiting
Elite Clinical Trials Blackfoot Idaho 83221 Recruiting
Central Illinois Diabetes and Clinical Research Springfield Illinois 62701 Recruiting
Elevate Clinical Research Lake Charles Louisiana 70605 Recruiting
Nola Care Clinical Research Center Metairie Louisiana 70006 Recruiting
DelRicht Clinical Research, LLC New Orleans Louisiana 70115 Recruiting
Centennial Medical Group Columbia Maryland 21045-5840 Recruiting
Olive Branch Family Medical Center Olive Branch Mississippi 38654 Recruiting
Kansas City VA Medical Center Kansas City Missouri 64128 Recruiting
Centricity Research Morehead City Multispeciality Morehead City North Carolina 28557 Recruiting
Wake Forest University Health Sciences Winston-Salem North Carolina 27157 Recruiting
Remington Davis Inc Columbus Ohio 43215 Recruiting
Lynn Institute of Norman Norman Oklahoma 73072 Recruiting
Lynn Health Science Institute Oklahoma City Oklahoma 73112 Recruiting
Essential Medical Research Tulsa Oklahoma 74137 Recruiting
VA Pittsburgh Healthcare System Pittsburgh Pennsylvania 15240 Recruiting
Coastal Carolina Research Center North Charleston South Carolina 29405 Recruiting
Circle Clinical Research Sioux Falls South Dakota 57104 Recruiting
Headlands Research Brownsville Brownsville Texas 78526 Recruiting
Velocity Clinical Research Dallas Texas 75230 Recruiting
South Texas Research Institute - Edinburg Edinburg Texas 78539 Recruiting
HRI ? Medical Center, LLC Houston Texas 77004 Recruiting
Juno Research, LLC Houston Texas 77040 Recruiting
HRI ? Pasadena, LLC Pasadena Texas 77505 Recruiting
Pinnacle Clinical Research - San Antonio San Antonio Texas 78229 Recruiting
DM Clinical Research Tomball Texas 77375 Recruiting
Manassas Clinical Research Center Manassas Virginia 20110 Recruiting
Centricity Research Suffolk Primary Care Suffolk Virginia 23435 Recruiting
Era Health Research Redmond Washington 98052 Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 177 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT07351058, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Nov 9, 2026 · Synced Nov 13, 2026

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