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Active, not recruiting Phase 3 Interventional

A Study of Retatrutide (LY3437943) in Participants Without Type 2 Diabetes Who Have Obesity or Overweight

ClinicalTrials.gov ID: NCT07357415

Public ClinicalTrials.gov record NCT07357415. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 3, 2026, 6:48 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 3b Study to Investigate the Efficacy and Safety of Different Retatrutide Dose Escalation Schemes in Participants Without Type 2 Diabetes Who Have Obesity or Overweight: A Randomized, Controlled, Double-Blind Trial

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to investigate the efficacy and safety of different retatrutide dose escalation schemes in participants without type 2 diabetes who have obesity or overweight. Participation in the study will last about 113 weeks.

Study identification

NCT ID
NCT07357415
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 3
Lead sponsor
Eli Lilly and Company
Industry
Enrollment
600 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jan 23, 2026
Primary completion
Sep 30, 2028
Completion
Oct 31, 2028
Last update posted
Jun 8, 2026

2026 – 2028

United States locations

U.S. sites
20
U.S. states
14
U.S. cities
18
Facility City State ZIP Site status
Arizona Research Center Phoenix Arizona 85053
Care Access - Huntington Beach Huntington Beach California 92648
Los Angeles Institute for Metabolic Research Los Angeles California 90015
New Horizon Research Center Miami Florida 33165
Encore Medical Research - Weston Weston Florida 33331
Pacific Diabetes & Endocrine Center Honolulu Hawaii 96817
Monroe Biomedical Research - Louisville Louisville Kentucky 40213
Brigham and Women's Hospital Diabetes Program Boston Massachusetts 02115
Great Lakes Research Group, Inc. Bay City Michigan 48706
NYC Research INC Long Island City New York 11106
Weill Cornell Medical College New York New York 10021
Care Access - Raleigh Raleigh North Carolina 27607
New Phase Research and Development Knoxville Tennessee 37909
Velocity Clinical Research, Dallas Dallas Texas 75230
Cedar Health Research - Texas Native Health Dallas Texas 75235
Cedar Health Research Dallas Texas 75251
Cedar Health Research - Fort Worth Fort Worth Texas 76132
Advanced Research Institute Ogden Utah 84405
Dominion Medical Associates, Inc. Richmond Virginia 23219
CAMC Institute for Academic Medicine Charleston West Virginia 25304

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 15 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT07357415, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jun 8, 2026 · Synced Sep 3, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT07357415 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →