Combination Antibiotic Therapy for Staphylococcus Aureus Bacteremia
Public ClinicalTrials.gov record NCT07376889. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
COMBAT-SAB: Combination Antibiotic Therapy for Staphylococcus Aureus Bacteremia
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to see if, in selected patients with a serious bacterial infection of the bloodstream, treating the bacterial infection with a combination of antibiotics is more effective than treating the infection with a single antibiotic. Participants must have blood cultures which are positive for a certain type of bacteria.
Study identification
- NCT ID
- NCT07376889
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 4
- Enrollment
- 2,096 participants
Conditions and interventions
Conditions
Interventions
- Antibiotic Monotherapy (AM) for patients with methicillin-sensitive S. aureus bacteremia (MSSAB) Drug
- Antibiotic Monotherapy (AM) for patients with methicillin-resistant S. aureus bacteremia (MRSAB) Drug
- Combination Antibiotic Therapy (CAT) for patients with methicillin-sensitive S. aureus bacteremia (MSSAB) Drug
- Combination Antibiotic Therapy (CAT) for patients with methicillin-resistant S. aureus bacteremia (MRSAB) Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 31, 2026
- Primary completion
- Dec 31, 2028
- Completion
- Dec 31, 2028
- Last update posted
- Aug 24, 2026
2026 – 2029
United States locations
- U.S. sites
- 13
- U.S. states
- 3
- U.S. cities
- 13
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Platte Valley Hospital | Brighton | Colorado | 80601 | Not yet recruiting |
| Saint Joseph Hospital | Denver | Colorado | 80218 | Not yet recruiting |
| St. Mary's Regional Hospital | Grand Junction | Colorado | 81501 | Not yet recruiting |
| Good Samaritan Hospital | Lafayette | Colorado | 80026 | Not yet recruiting |
| Lutheran Medical Center | Wheat Ridge | Colorado | 80401 | Not yet recruiting |
| St. Vincent Regional Hospital | Billings | Montana | 59101 | Not yet recruiting |
| St. James Hospital | Butte | Montana | 59701 | Not yet recruiting |
| Holy Rosary Hospital | Miles City | Montana | 59301 | Not yet recruiting |
| Intermountain Medical Center | Murray | Utah | 84107 | Recruiting |
| McKay-Dee Hospital | Ogden | Utah | 84403 | Not yet recruiting |
| Utah Valley Hospital | Provo | Utah | 84604 | Not yet recruiting |
| LDS Hospital | Salt Lake City | Utah | 84143 | Not yet recruiting |
| St. George Regional Hospital | St. George | Utah | 84790 | Not yet recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07376889, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 24, 2026 · Synced Sep 5, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07376889 live on ClinicalTrials.gov.