A Study of Safety and Drug Levels of ePGT121v1-LS, PGDM1400LS, and VRC07-523LS in Adult Participants Without HIV-1
Public ClinicalTrials.gov record NCT07390955. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 1 Clinical Trial to Evaluate the Safety, Pharmacokinetics, and in Vitro Neutralization of ePGT121v1-LS, PGDM1400LS, and VRC07-523LS Administered in Multiple Doses and Routes to Adult Participants Without HIV-1
Study identification
- NCT ID
- NCT07390955
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 1
- Lead sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
- NIH
- Enrollment
- 83 participants
Conditions and interventions
Conditions
Interventions
- PGDM1400LS (IV) Biological
- PGDM1400LS (SC) Biological
- VRC07-523LS (IV) Biological
- VRC07-523LS (SC) Biological
- ePGT121v1-LS (IV) Biological
- ePGT121v1-LS (SC) Biological
Biological
Eligibility (public fields only)
- Age range
- 18 Years to 55 Years
- Sex
- All
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 18, 2026
- Primary completion
- Aug 29, 2027
- Completion
- Aug 29, 2027
- Last update posted
- Apr 21, 2026
2026 – 2027
United States locations
- U.S. sites
- 8
- U.S. states
- 8
- U.S. cities
- 8
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Alabama CRS (Site ID: 31788) | Birmingham | Alabama | 35222 | Recruiting |
| Bridge HIV CRS (Site ID: 30305) | San Francisco | California | 94102 | Recruiting |
| George Washington University CRS (Site ID: 31608) | Washington D.C. | District of Columbia | 20052 | Not yet recruiting |
| The Ponce de Leon Center CRS (Site ID: 5802) | Atlanta | Georgia | 30308 | Not yet recruiting |
| Brigham and Women's Hospital Vaccine CRS (BWH VCRS) (Site ID: 30007) | Boston | Massachusetts | 02115 | Not yet recruiting |
| Penn Prevention CRS (Site ID: 30310) | Philadelphia | Pennsylvania | 19104 | Not yet recruiting |
| Vanderbilt Vaccine (VV) CRS (Site ID: 30352) | Nashville | Tennessee | 37232 | Recruiting |
| Houston Advancing Research Team CRS (Site ID: 31473) | Houston | Texas | 77030 | Not yet recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 4 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07390955, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 21, 2026 · Synced Apr 23, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07390955 live on ClinicalTrials.gov.