KQB198 in Combination With Imatinib in Participants With Advanced/Metastatic GIST in 1st Line Setting

ClinicalTrials.gov ID: NCT07406633

Public ClinicalTrials.gov record NCT07406633. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced May 21, 2026, 1:52 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2, Multicenter, Study Evaluating the Efficacy, Safety, Tolerability, Pharmacokinetics of KQB198 in Combination With Imatinib in Participants With Advanced/Metastatic GI Stromal Tumor in 1st Line Setting

Study identification

NCT ID: NCT07406633
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 2
Lead sponsor: Kumquat Biosciences Inc.; Industry
Enrollment: 46 participants

Conditions and interventions

Conditions

Interventions

Imatinib (Gleevec) Drug
KQB198 Drug

Drug

Eligibility (public fields only)

Age range: 18 Years and older
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Apr 30, 2026
Primary completion: Sep 30, 2027
Completion: Sep 30, 2028
Last update posted: May 18, 2026

2026 – 2028

United States locations

U.S. sites: 8
U.S. states: 7
U.S. cities: 8

Facility	City	State	ZIP	Site status
USC Norris Comprehensive Cancer Center	Los Angeles	California	90033	Recruiting
Mayo Clinic - Jacksonville	Jacksonville	Florida	32224	Recruiting
Moffitt Cancer Center	Tampa	Florida	33612	Recruiting
University of Michigan Hospitals	Ann Arbor	Michigan	48109	Recruiting
Mayo Clinic - Rochester	Rochester	Minnesota	55905	Recruiting
Cleveland Clinic	Cleveland	Ohio	44195	Recruiting
UT MD Anderson Cancer Center	Houston	Texas	77030	Recruiting
Fred Hutchinson Cancer Center	Seattle	Washington	98195	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT07406633, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted May 18, 2026 · Synced May 21, 2026

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The complete protocol, eligibility criteria, and contact information for NCT07406633 live on ClinicalTrials.gov.

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