A Study to Assess the Safety and Efficacy of Different Doses of ELV001 to Treat Active Rheumatoid Arthritis in Patients With an Inadequate Response to Methotrexate and Tumor Necrosis Factor Inhibition (START SYNERGY)
Public ClinicalTrials.gov record NCT07409103. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Randomized, Double-blind, Placebo-controlled Study to Investigate the Safety and Efficacy of ELV001 as Add-on Therapy in Patients With Active Rheumatoid Arthritis and Inadequate Response to Methotrexate and Tumor Necrosis Factor Inhibition (START SYNERGY)
Study identification
- NCT ID
- NCT07409103
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Elevara Medicines Limited
- Industry
- Enrollment
- 180 participants
Conditions and interventions
Conditions
Interventions
- ELV001 125 mg Drug
- ELV001 25 mg Drug
- ELV001 75 mg Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 17, 2026
- Primary completion
- Apr 14, 2027
- Completion
- Mar 30, 2028
- Last update posted
- Apr 22, 2026
2026 – 2028
United States locations
- U.S. sites
- 22
- U.S. states
- 9
- U.S. cities
- 21
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Arizona Arthritis & Rheumatology Associates | Gilbert | Arizona | 85032 | Recruiting |
| Arizona Arthritis & Rheumatology Associates | Glendale | Arizona | 85306 | Recruiting |
| Arizona Arthritis & Rheumatology Associates | Tucson | Arizona | 85704 | Recruiting |
| Solace Clinical Research - Populace Health (Network) | Tustin | California | 92780 | Recruiting |
| Denver Arthritis Clinic | Denver | Colorado | 80230 | Recruiting |
| Rheumatology Associates of South Florida-Clinical Research Inc - Cliniverse Research (Network) | Boca Raton | Florida | 33486 | Recruiting |
| Prophase, LLC - Clinitiative Health Research (Network) | Margate | Florida | 33063 | Recruiting |
| Millennium Medical Research LLC - Clinitiative Health Research (Network) | Miami | Florida | 33126 | Recruiting |
| Floridian Clinical Research, LLC - Clinitiative Health Research (Network) | Miami Beach | Florida | 33016 | Recruiting |
| Bioresearch Partner - Cliniverse Research (Network) | South Miami | Florida | 33143 | Recruiting |
| Accurate Clinical Research Inc (SMO/ Network) | Lake Charles | Louisiana | 70605 | Recruiting |
| Great Lakes Center of Rheumatology | Lansing | Michigan | 48911 | Recruiting |
| DJL Clinical Research PLLC (Network) cIRB | Charlotte | North Carolina | 28262 | Recruiting |
| Carolina Arthritis Associates - Cliniverse Research (Network) | Wilmington | North Carolina | 28401 | Recruiting |
| Altoona Arthritis & Osteoporosis Center | Duncansville | Pennsylvania | 16635 | Recruiting |
| Pennsylvania Regional Center for Arthritis & Osteoporosis Research | Wyomissing | Pennsylvania | 19610 | Recruiting |
| Accurate Clinical Management, LLC. - Accurate Clinical Research Inc (SMO/ Network) | Baytown | Texas | 77521 | Recruiting |
| Accurate Clinical Research Inc (SMO/ Network) | Houston | Texas | 77089 | Recruiting |
| Heights Rheumatology and Aesthetics - ES Clinical Research Group Network | Jackson | Texas | 11372 | Recruiting |
| Epic Medical Research-Red Oak | Red Oak | Texas | 78666 | Recruiting |
| DM Clinical Research (Network) | Tomball | Texas | 77375 | Recruiting |
| DM Clinical Research (Network) | Tomball | Texas | 77377 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 7 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07409103, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 22, 2026 · Synced May 10, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07409103 live on ClinicalTrials.gov.