A Study of Brenipatide in Adult Participants With Major Depressive Disorder
Public ClinicalTrials.gov record NCT07412756. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Multicenter, Randomized, Double-Blind, Parallel-Arm Study to Investigate the Efficacy and Safety of Adjunctive Treatment With Brenipatide in Delaying Time to Relapse Compared With Placebo in Adult Participants With Major Depressive Disorder (RENEW-MDD 1)
Study identification
- NCT ID
- NCT07412756
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Eli Lilly and Company
- Industry
- Enrollment
- 1,000 participants
Conditions and interventions
Conditions
Not listed
Interventions
Not listed
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 8, 2026
- Primary completion
- Jan 31, 2028
- Completion
- Jan 31, 2028
- Last update posted
- Mar 22, 2026
2026 – 2028
United States locations
- U.S. sites
- 32
- U.S. states
- 20
- U.S. cities
- 32
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Accellacare - Moorpark | Moorpark | California | 93021 | Not yet recruiting |
| ATP Clinical Research | Orange | California | 92866 | Recruiting |
| Yale University School of Medicine | New Haven | Connecticut | 06519 | Not yet recruiting |
| Encore Medical Research | Hollywood | Florida | 33024 | Not yet recruiting |
| K2 Medical Research - Maitland | Maitland | Florida | 32751 | Not yet recruiting |
| Life Medical Research Group Corp | Miami Gardens | Florida | 33014 | Recruiting |
| Floridian Clinical Research, LLC | Miami Lakes | Florida | 33016-1518 | Not yet recruiting |
| CLA Research | Naples | Florida | 34116 | Not yet recruiting |
| Optimal Research Sites | Orange City | Florida | 32763 | Recruiting |
| Charter Research - Orlando | Orlando | Florida | 32803 | Recruiting |
| K2 Medical Research - Tampa | Tampa | Florida | 33634 | Not yet recruiting |
| CenExel iResearch, LLC | Decatur | Georgia | 30030 | Recruiting |
| Indiana University Health Neuroscience Center | Indianapolis | Indiana | 46202 | Recruiting |
| Cedar Valley Medical Specialists | Waterloo | Iowa | 50701 | Not yet recruiting |
| Pharmasite Research, Inc. | Baltimore | Maryland | 21208 | Recruiting |
| Adams Clinical Boston | Boston | Massachusetts | 02116 | Recruiting |
| Adams Clinical Watertown | Watertown | Massachusetts | 02472 | Recruiting |
| Arcturus Healthcare , PLC, Troy Internal Medicine Research Division | Troy | Michigan | 48098 | Not yet recruiting |
| Arch Clinical Trials | St Louis | Missouri | 63141 | Not yet recruiting |
| Vector Clinical Trials | Las Vegas | Nevada | 89128 | Recruiting |
| Adams Clinical Harlem | New York | New York | 10029 | Recruiting |
| Summit Headlands | Portland | Oregon | 97210 | Not yet recruiting |
| Suburban Research Associates | Media | Pennsylvania | 19063 | Recruiting |
| Penn Medicine: University of Pennsylvania Health System | Philadelphia | Pennsylvania | 19104 | Not yet recruiting |
| K2 Medical Research - East Providence | East Providence | Rhode Island | 02914 | Not yet recruiting |
| Circle Clinical Research | Sioux Falls | South Dakota | 57104 | Not yet recruiting |
| Adams Clinical Dallas | DeSoto | Texas | 75115 | Recruiting |
| Re:Cognition Health - Fort Worth | Fort Worth | Texas | 76104 | Recruiting |
| Consano Clinical Research, LLC | Shavano Park | Texas | 78231 | Not yet recruiting |
| Alpine Research Organization | Clinton | Utah | 84015 | Recruiting |
| Re:Cognition Health | Fairfax | Virginia | 22031 | Not yet recruiting |
| Northwest Clinical Research Center | Bellevue | Washington | 98007 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 67 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07412756, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 22, 2026 · Synced May 17, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07412756 live on ClinicalTrials.gov.